Supplier: STEMCELL Technologies

Interleukin-8 (IL-8) is a member of the CXC subfamily of chemokines and is produced by leukocytic cells (monocytes, T cells, neutrophils, and natural killer cells) and non-leukocytic somatic cells (endothelial cells, fibroblasts, and epithelial cells), with the most prominent source being monocytes and macrophages. Its production is induced by inflammatory stimuli, such as IL-1. IL-8, also known as CXCL8, activates neutrophils inducing chemotaxis, exocytosis, and the respiratory burst (Baggiolini and Clark-Lewis; Mukaida). IL-8 is considered one of the most potent neutrophil chemoattractants in inflammation and binds to two different chemokine receptors on leukocytes: the G protein-coupled receptors CXCR1 and CXCR2 (Hoffmann et al.; de Oliveira et al.). IL-8 has angiogenic effects on human intestinal microvascular endothelial cells in vitro that are mediated by CXCR2 (Heidemann et al.). IL-8 is reported to promote breast cancer progression by increasing cell invasion, angiogenesis, and metastasis and has been reported to be involved in regulating breast cancer stem-like cells (Singh et al.). IL-8 also has proangiogenic properties in inflammatory diseases of the conjunctiva, cornea, iris, retina, and orbit (Ghasemi et al.). It was also shown that a major T cell effector function in human newborns is IL-8 production, which has the potential to activate antimicrobial neutrophils and gamma/delta T cells (Gibbons et al.). A variety of human pathogens, such as HIV and Mycobacterium tuberculosis, have been shown to induce IL-8 production by monocytes and macrophages (Friedland et al.; Meddows-Taylor et al.).

Supplier: OMEGA BIO-TEK

E.Z.N.A.® Plasmid Midi Kit offers a novel and reliable method of isolating up to 200 µg of plasmid DNA in less than 60 minutes. This kit combines HiBind® membrane technology with the time-tested consistency of alkaline SDS lysis of bacterial cells to deliver high-quality plasmid DNA. The DNase/RNase-free HiBind® DNA midi columns operate by eliminating time consuming phenol-chloroform extractions and alcohol precipitations. Plasmid purification using the E.Z.N.A.® Plasmid Midi Kit follows a simple bind-wash-elute procedure thereby making it possible for multiple samples to be processed. Although yields vary according to plasmid copy number, E.coli strain, and conditions of growth, 50 ml of an overnight culture in LB medium will typically produce 200 µg of high-copy number plasmid DNA. When working with low-copy number plasmids the starting culture volume can be increased up to 100 ml. High-quality DNA is ready for immediate use in routine molecular biology applications, such as automated fluorescent sequencing, restriction enzyme digestion, and transfection screening.

Supplier: Thermo Fisher Scientific

L(+)-Potassium sodium tartrate tetrahydrate 99+% for analysis

Supplier: ACROBIOSYSTEMS

MABSol® Biotinylated Human ErbB3, His Tag, primary amine labeling (ER3-H8223) is expressed from human HEK293 cells. It contains AA Ser 20 - Thr 643 (Accession NP001973.2). It is the biotinylated form of Human ErbB3, His Tag (ER3-H5223). null

Supplier: ACROBIOSYSTEMS

MABSol® Biotinylated Human B7-H4, His Tag, primary amine labeling (B74-H8222) is expressed from human HEK293 cells. It contains AA Phe 29 - Ala 258 (Accession NP078902). It is the biotinylated form of Human B7-H4, His Tag (Cat. No. B74-H5222). null

Supplier: MP Biomedicals

The FastRNA™ SPIN Kit for Yeast quickly and efficiently isolates high-quality, total RNA from tough-to-lyse yeast strains, fungi, and algae in approximately 15 minutes using a specialised Lysing Matrix (Yttria-stabilised zirconium oxide, 0,5 mm) for cell lysis and SPIN columns for the purification process.

Supplier: Roth Carl

di-Sodium L(+)-tartrate dihydrate

Supplier: Spectrum Chemical

Form: Powder

Supplier: G-Biosciences

The majority of genomic DNA extraction methods involve numerous physical manipulations, including mixing, pipetting, shaking, binding to resin, elution, which results in sheared DNA that may not be suitable for further analysis.

Supplier: Merck

Sodium deoxycholate monohydrate, Sigma-Aldrich®

Supplier: Thermo Fisher Scientific

Antimony(III) potassium oxitartrate trihydrate 99.0-103.0% ACS

Supplier: Thermo Fisher Scientific

Antimony(III) potassium oxitartrate trihydrate 99+%

Supplier: Thermo Fisher Scientific

L(+)-Histidine monohydrochloride monohydrate 98%

Supplier: MP Biomedicals

The Fast DNA™ SPIN Kit for Soil is designed to efficiently isolate bacterial, fungal, plant and animal genomic DNA from soil and other environmental samples. It quickly and efficiently isolates PCR-ready genomic DNA directly from soil samples in less than 60 minutes.

Supplier: Merck

Sodium deoxycholate (SDC) monohydrate is a bile acid salt used in the solubilization of estrogen synthetase from human placental microsomes.

Supplier: Thermo Fisher Scientific

di-Sodium L(+)-tartrate dihydrate 99+% ACS

Supplier: Cytiva

Sera-Xtracta virus/pathogen kit for high-throughput total nucleic acid (DNA/RNA) isolation from bacteria and viruses including adenovirus (type 14), influenza A (H3N2) and COVID-19.

Supplier: Merck

L(+)-Potassium sodium tartrate tetrahydrate, Sigma-Aldrich®

Supplier: Thermo Fisher Scientific

L(+)-Cysteine hydrochloride monohydrate 98.5-101.5% (dry basis)

Supplier: Thermo Fisher Scientific

L(+)-Potassium sodium tartrate tetrahydrate ACS

Supplier: Merck

L(+)-Cysteine hydrochloride monohydrate, Sigma-Aldrich®

Supplier: Spectrum Chemical

Calcium Lactate, Pentahydrate, USP, FCC, EP is a filler/diluent excipient.

Supplier: MP Biomedicals

Cysteine is a major biological source of sulphur and is one of the two common sulphur-containing amino acids. It is a NMDA glutamatergic receptor antagonist.

Supplier: Merck

L(+)-Histidine monohydrochloride monohydrate, Sigma-Aldrich®

Supplier: MP Biomedicals

L-Histidine has been used to study cultures of the human T-lymphoblastic leukemia cell line MOLT-4 to study modulation of apoptosis. Exogenous histidine has been shown to enhance the biosynthesis of lovastatin by cultured Aspergillus terreus. Histidine has been utilised as a single nitrogen source to probe swarming in Pseudomonas aeruginosa on agar. An in vivo study has used L-histidine to diminish the net secretory response of the small intestine of of cholera toxin-challenged mice.

Supplier: Thermo Fisher Scientific

Sodium-L(+)-glutamate monohydrate 99%

Supplier: Avantor

Sodium-L(+)-glutamate monohydrate 98.5-101.5% (dried basis), BAKER FCC, Laboratory Reagent, J.T.Baker®

Supplier: Spectrum Chemical

Monosodium L-Glutamate, FCC is used in the food industry as a flavor with an umami taste. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.