1,1-Dimethylbiguanide hydrochloride (Metformin) is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.

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9H-Fluoren-9-ylmethyl 2-hydroxy-1,1-dimethylethylcarbamate

Supplier: Apollo Scientific

9H-Fluoren-9-ylmethyl 2-hydroxy-1,1-dimethylethylcarbamate

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2-(1,1-Dioxidothiomorpholin-4-yl)-3,3-dimethylbutanoic acid

Supplier: Apollo Scientific

2-(1,1-Dioxidothiomorpholin-4-yl)-3,3-dimethylbutanoic acid

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2-Di-t-butylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl

Supplier: Apollo Scientific

2-Di-t-butylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl

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3'-Amino-[1,1'-biphenyl]-3-carboxylic acid hydrochloride

Supplier: Apollo Scientific

3'-Amino-[1,1'-biphenyl]-3-carboxylic acid hydrochloride

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(±)11(12)-EET methyl ester solution ≥98% in ethanol

Supplier: Cayman Chemical

(±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. (±)11(12)-EET has been shown, along with (±)8(9)-EET, to play a role in the recovery of depleted Ca²⁺ pools in cultured smooth muscle cells.

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Methyl-4'-chloro-3'-fluoro[1,1'-biphenyl]-4-carboxylate

Supplier: Apollo Scientific

Methyl-4'-chloro-3'-fluoro[1,1'-biphenyl]-4-carboxylate

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4'-Chloro-3'-fluoro[1,1'-biphenyl]-4-carboxylic acid

Supplier: Apollo Scientific

4'-Chloro-3'-fluoro[1,1'-biphenyl]-4-carboxylic acid

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Methyl-4'-bromo-4-nitro[1,1'-biphenyl]-2-carboxylate

Supplier: Apollo Scientific

Methyl-4'-bromo-4-nitro[1,1'-biphenyl]-2-carboxylate

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3-(2-Fluoro-1,1'-biphenyl-4-yl)-1H-pyrazole

Supplier: Apollo Scientific

3-(2-Fluoro-1,1'-biphenyl-4-yl)-1H-pyrazole

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1,2-Dibromo-1,1-dichloro-2,2-difluoroethane 97%

Supplier: Apollo Scientific

1,2-Dibromo-1,1-dichloro-2,2-difluoroethane 97%

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2-Chlorodibenzo[b,f]-1,4-oxazepin-11(10H)-one 97%

Supplier: Thermo Fisher Scientific

2-Chlorodibenzo[b,f]-1,4-oxazepin-11(10H)-one 97%

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(E)-(3-{[1,1'-Biphenyl]-4-yl}-3-oxopropylidene)(methyl)oxidoazanium, tech

Supplier: Apollo Scientific

(E)-(3-{[1,1'-Biphenyl]-4-yl}-3-oxopropylidene)(methyl)oxidoazanium, tech

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10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine 98%

Supplier: Apollo Scientific

10,11-Dihydro-11-oxodibenzo[b,f][1,4]thiazepine 98%

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Benzo[b]thiophene-3(2H)-one 1,1-dioxide 95%

Supplier: Apollo Scientific

Benzo[b]thiophene-3(2H)-one 1,1-dioxide 95%

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4-(1,1'-Biphenyl-4-yl)-1,3-thiazol-2-amine 97%

Supplier: Thermo Fisher Scientific

4-(1,1'-Biphenyl-4-yl)-1,3-thiazol-2-amine 97%

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4'-(1,3-Dioxolan-2-yl)[1,1'-biphenyl]-4-carbaldehyde 95%

Supplier: Apollo Scientific

4'-(1,3-Dioxolan-2-yl)[1,1'-biphenyl]-4-carbaldehyde 95%

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1,1-Dimethylbiguanide hydrochloride 98%, white crystalline powder

Supplier: MP Biomedicals

1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.