112966 Results for: "Trolleys&pageNo=10&view=list"

Supplier: IKA

IKA MIXSTER is a universal and compact mixing device with magnetic drive. In the default version, IKA MIXSTER is a powerful single-position magnetic stirrer for mixing up to 5 litres at a maximum speed of 3000 min⁻¹ and a viscosity of up to 500 mPa·s. By connecting additional IKA MIXSTER stirring units (available as accessories, IKAA20112621), IKA MIXSTER can be expanded to a multi-position magnetic stirrer with up to 30 stirring positions. The stirring positions can be controlled either separately or simultaneously (leader-follower principle).

Supplier: CHIRAL TECHNOLOGIES

COLUMN CHIRALPAK WH 50X4.6MM 10µM 1 * 1 items

Supplier: Hospidex

Microsyringe 10µl with plunger and interchangeable needle 1 * 1 items

Supplier: OMNIFIT

Frits, ptfe, 40 micron for 10mm endpieces 1 * 20 items

Supplier: Merck

CelLytic(TM) B Cell Lysis Reagent For bacterial cell lysis, 10× concentrate 1 * 100 mL

Supplier: STEMCELL Technologies

Interleukin 21 (IL-21) is a pleiotropic cytokine that is composed of four α-helical bundles and primarily produced by natural killer T (NKT) cells, T follicular helper (Tfh) cells, and Th17 cells (Spolski and Leonard 2008). IL-21 signals via receptor heterodimerization of IL-21 receptor and IL-2 receptor subunit gamma (IL-2RG or CD132), both of which have a common gamma-chain subunit and activate the JAK/STAT, MAPK, and PI3K pathways (Parrish-Novak et al.; Ozaki et al. 2000; Spolski and Leonard 2014). IL-21 has been shown to have a critical role in regulating immunoglobulin production and differentiation of the pro-inflammatory Th17 population of cells (Ozaki et al. 2002; Nurieva et al.). Additionally, IL-21 specifically sustains CD8+ T cell effector activity and provides a mechanism of CD4+ T cell help during chronic viral infection (Elsaesser et al.). IL-21 signaling was also found critical for the development of type 1 diabetes in non-obese diabetic (NOD) mice (Sutherland et al.) and control of T cell autoimmunity by regulatory B cells (Yoshizaki et al.).

Supplier: Brand

PP. These 0,2 and 0,5 ml PCR tubes with attached caps are compatible with leading thermal cyclers with heated lids.

Supplier: STEMCELL Technologies

Platelet-derived growth factor (PDGF) is a dimeric glycoprotein consisting of two disulfide bridge-stabilized polypeptide chains, A and B, which are assembled as heterodimers (PDGF-AB) or homodimers (PDGF-AA and PDGF-BB) (Fretto et al.; Westermark and Heldin). PDGF signals through the receptor tyrosine kinases PDGFRalpha and PDGFRbeta. PDGF-induced migration has been shown to involve MEK/ERK, EGFR, Src, and PI3K/Akt signaling pathways (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin- like fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). PDGF-BB is secreted by osteoblasts to induce mesenchymal stem cell migration and angiogenesis. It has also been shown that PDGF-BB is secreted by preosteoclasts during bone modeling and remodeling to induce angiogenesis and thus proper osteogenesis (Xie et al.). This product is animal component-free.

Supplier: NEUBERT VOLUME GLASSWAERE

flat bottom glass 36x1,4x120mm 54mm with ring mark fused straight bottom ca.45ml ring mark mark at 54+-0,5mm inside measured straight bottom straight rim fused (pour point glass ) from Boro 3.3 1 * 1 items

Supplier: bimos

Apart from special hygiene features, a laboratory chair must always be ready for use at changing places of work. It should take up a minimum of space yet still offer maximum ergonomics and seating comfort so as to guarantee precise and concentrated work over longer periods of time. Labster is ideal for everyday use in the laboratory.

Supplier: VACUUBRAND

The VacuuCenter BVC professional serves for aspiration and disposal of biological fluids, providing outstanding levels of comfort and safety for working with biological and biohazardous materials. A non contact sensor monitors the liquid level in the collection bottle electronically and prevents overfilling. A disinfection routine allows the suction of disinfectants through an aspiration hand set and tubing after switching off the pump, and so supports demanding safety protocols. The BVC professional with 4 litre PP bottle that has self-closing quick couplings minimises risk in transporting hazardous waste and of contamination in the workplace. The version with coated 2 litre borosilicate glass bottle allows the user to work with aggressive disinfectants like chlorine bleach.

Supplier: ProSci Inc.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Supplier: ProSci Inc.

FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing.This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.

Supplier: STEMCELL Technologies

Leukemia inhibitory factor (LIF) is an interleukin 6 class cytokine that regulates a broad variety of developmental functions. After LIF binds to the LIF receptor (LIFR), LIFR associates with gp130 and activates JAK/STAT and MAPK signaling (Auernhammer and Melmed; Suman et al.). LIFR activation of STAT3 is essential for maintaining the mouse embryonic stem cell phenotype (Niwa et al.). Produced by the endometrium, LIF plays an important autocrine and paracrine role in implantation by regulating proliferation, invasion, and differentiation of trophoblasts following blastocyst attachment (Auernhammer and Melmed; Suman et al.). Human LIF can be used for the maintenance of mouse embryonic stem cells; however, mouse LIF cannot bind to the human receptor, thus rendering mouse LIF inactive (Dahéron et al.). LIF is produced by CD4+ and activated regulatory T cells, and promotes Foxp3 expression, while repressing Th17 lineage-specific genes (Metcalfe). LIF is also secreted by mesenchymal stromal cells, where it supports hematopoiesis and immune modulation (Nasef et al.).

Supplier: TRESTON

Hook R1, L150 /10kg (5pcs),L150 /10kg (5pcs) 1 * 1 items

Supplier: Abnova

Recombinant protein, tada2l( aah01172, 1 a.a. - 306 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, mef2c( aah26341.1, 1 a.a. - 469 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, adam11( np_002381, 230 a.a. - 333 a.a.) partial recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, prc1( aah03138.1, 1 a.a. - 621 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, chd2( aah07347, 1 a.a. - 502 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, iqcb1( np_001018865.1, 1 a.a. - 465 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, hoxc9( aah53894, 1 a.a. - 261 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, nmu( aah12908, 36 a.a. - 175 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, mbnl2( aai04040.1, 1 a.a. - 373 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, ntf3( np_002518.1, 1 a.a. - 257 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, prame( aah39731, 1 a.a. - 510 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cyp11a1( aah32329.1, 1 a.a. - 521 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, g6pc( np_000142.1, 1 a.a. - 357 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: VARIAN

TUBING SS REG 10MX1/16INCHX0.75 EA=10MR 1 * 1 items

Supplier: Abnova

Recombinant protein, flj10774( np_078938, 2 a.a. - 98 a.a.) partial recombinant protein with gst tag. 1 * 2 µG