112981 Results for: "Tetrakis(hydroxymethyl)phosphonium+chloride&pageNo=10&view=list"

Supplier: Abnova

Recombinant protein, dlst( np_001924, 1 a.a. - 99 a.a.) partial recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cap1( aah13963, 1 a.a. - 476 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, silv( np_008859.1, 1 a.a. - 661 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: STEMCELL Technologies

Betacellulin is a member of the epidermal growth factor (EGF) family, and signals through EGF receptor and ERBB4. It activates ERK and AKT pathways, which induces neural stem cell proliferation and prevents spontaneous differentiation in culture. Betacellulin stimulates the expansion of neural stem cells, transit-amplifying cells, and neuroblasts derived from subventricular zone and dentate gyrus (Gómez-Gaviro et al.). It is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin down-regulates E-cadherin expression in ovarian cancer cell lines via MEK/ERK1/2 and PI3K/AKT signaling pathways, thus increasing cell migration (Zhao et al.). It is a modulator of interferon (IFN) response and enhances anti-viral effects of IFN (Al-Yahya et al.). Betacellulin is expressed in pancreatic α cells, β cells, and duct cells. It induces the proliferation of pancreatic cancer cell lines, inhibits apoptosis, promotes the neogenesis of β cells, and converts non-β cells into insulin-producing cells (Kawaguchi et al.; Miyagawa al.; Saito et al.).

Supplier: STEMCELL Technologies

Receptor activator of nuclear factor kappa-B ligand (RANKL) is a member of the tumor necrosis factor (TNF) superfamily (Anderson et al.). Cytokines in the TNF superfamily are involved in a variety of long-term cellular activities such as differentiation, proliferation, and cell death (MacEwan). RANKL is a type II homotrimeric transmembrane protein expressed in both a membrane-bound and secreted form (Ikeda et al.). RANKL binds to the receptor activator of nuclear factor kappa-B (RANK). Upon binding to its receptor, RANKL activates the AKT signaling pathway (Moon et al.). Osteoprotegerin (OPG) may also bind RANKL, and this binding competes with RANKL-RANK binding (Lacey et al.). RANKL is involved in osteoclastogenesis (Lacey et al.; Yasuda et al.) and T cell activation (Wong et al.).

Supplier: STEMCELL Technologies

Interleukin 9 (IL-9) has pleiotropic functions in the immune system and signals through its specific IL-9 receptor (IL-9R) (Renauld et al.). IL-9/IL-9R signaling pathway mainly targets the downstream activation of JAK/STAT (janus kinase/signal transducer and activator of transcription) and subsequent phosphorylation cascades initiated by multiple kinases including IRS–PI3K–PKB (insulin receptor substrate, phosphatidyl-inositol 3-kinases, protein kinase-B) and ERK (Knoops and Renauld; Fontaine et al.). IL-9 has been shown to have a role in Th1/Th17-mediated inflammation and in regulatory T cell responses (Singh et al.; Goswami and Kaplan). IL-9/IL-9R signaling pathway represents a novel endogenous anti-apoptotic mechanism for cortical neurons (Fontaine et al.). IL-9 secreting T cells, termed Th9 cells, contribute to both effective immunity and immunopathological disease, and have been shown to have a role in the treatment of allergic and autoimmune disease (Kaplan et al.).

Supplier: ProSci Inc.

BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers. Processed human BAFF can either remain as a trimer, which is usual for TNF family ligands or assemble into 60-mer composed of 20 trimers. Mouse BAFF 60-mer has been identified in the serum of BAFF transgenic mice. Oligomerisation of BAFF 3-mer into 60-mer in human BAFF is prevented by mutation of His218, a residue critical for 3-mer-to-3-mer interactions, but not for receptor binding. Despite the predominant functional role of processed BAFF in vivo, membrane-bound BAFF might also play a role. Indeed, soluble BAFF (3-mer) can trigger BAFF-R but not TACI or BCMA, whereas oligomeric forms of BAFF (BAFF 60-mer), which mimic membrane-bound BAFF, activate all BAFF receptors.

Supplier: Restek

Blood Alcohol Mix 0.16 g/dL Forensic Ethanol, Di Water, 1mL, 10pk 1 * 1 Each

Supplier: TRESTON

Middle plate 90-130/100 L=100 1 * 1 items

Supplier: MBV

LID 300HOLES EDGE PROT. F/MAS 100ISO/NT 1 * 1 items

Supplier: Abnova

Recombinant protein, vps52( np_542131, 625 a.a. - 723 a.a.) partial recombinant protein with gst tag. 1 * 2 µG

Supplier: DELTA T

BlueLineBox 10L with 1 x 22 DEG TEMPSHELL and 2.5 TEMPFRAMES 1 * 1 items

Supplier: DELTA T

BlueLineBox 10L with 1 x -30 DEG TEMPSHELL and 2.5 TEMPFRAMES 1 * 1 items

Supplier: Abnova

Recombinant protein, foxo3( aah20227.1, 1 a.a. - 673 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, pdia6( aah01312, 1 a.a. - 441 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cldn10( np_008915.1, 1 a.a. - 228 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cldn1( aah12471.1, 1 a.a. - 212 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, atp6v1a( aah13138, 1 a.a. - 618 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cblb( aah32851.1, 1 a.a. - 982 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: DWK Life Sciences

BLOCK HEATING ALUMINUM 14/10KITS 1 * 1 items

Supplier: Abnova

Recombinant protein, wdr5( np_060058, 16 a.a. - 120 a.a.) partial recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, pcdhgc5( np_115783.1, 1 a.a. - 878 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, pcdh8( aah36025.1, 1 a.a. - 1070 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, trim34( np_569073.1, 1 a.a. - 243 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, lect1( np_008946.1, 1 a.a. - 334 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, camk2g( aah34044, 1 a.a. - 528 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, dgat2( np_115953.2, 1 a.a. - 388 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, kcnmb2( aah17825, 1 a.a. - 236 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: SARSTEDT

HOLDER TUBE WITH CLIP 10CM 1 * 15 items

Supplier: TRESTON

Middle dividers and plates 1, drawer 70/100 1 * 1 items