113377 Results for: "Skin+Creams&pageNo=10&view=easy"
Human Recombinant IL-9
Supplier: STEMCELL Technologies
Interleukin 9 (IL-9) has pleiotropic functions in the immune system and signals through its specific IL-9 receptor (IL-9R) (Renauld et al.). IL-9/IL-9R signaling pathway mainly targets the downstream activation of JAK/STAT (janus kinase/signal transducer and activator of transcription) and subsequent phosphorylation cascades initiated by multiple kinases including IRS–PI3K–PKB (insulin receptor substrate, phosphatidyl-inositol 3-kinases, protein kinase-B) and ERK (Knoops and Renauld; Fontaine et al.). IL-9 has been shown to have a role in Th1/Th17-mediated inflammation and in regulatory T cell responses (Singh et al.; Goswami and Kaplan). IL-9/IL-9R signaling pathway represents a novel endogenous anti-apoptotic mechanism for cortical neurons (Fontaine et al.). IL-9 secreting T cells, termed Th9 cells, contribute to both effective immunity and immunopathological disease, and have been shown to have a role in the treatment of allergic and autoimmune disease (Kaplan et al.).
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Human recombinant BAFF (active) (soluble) (from E. coli)
Supplier: ProSci Inc.
BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases such as Sjoegren syndrome, Rheumatoid arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF has also increased levels in some lymphoid cancers. Processed human BAFF can either remain as a trimer, which is usual for TNF family ligands or assemble into 60-mer composed of 20 trimers. Mouse BAFF 60-mer has been identified in the serum of BAFF transgenic mice. Oligomerisation of BAFF 3-mer into 60-mer in human BAFF is prevented by mutation of His218, a residue critical for 3-mer-to-3-mer interactions, but not for receptor binding. Despite the predominant functional role of processed BAFF in vivo, membrane-bound BAFF might also play a role. Indeed, soluble BAFF (3-mer) can trigger BAFF-R but not TACI or BCMA, whereas oligomeric forms of BAFF (BAFF 60-mer), which mimic membrane-bound BAFF, activate all BAFF receptors.
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Test Sieve 400/65 mm, mesh = 0.16 mm ISO 3310-1 1 * 1 items
Supplier: FRITSCH
Test Sieve 400/65 mm, mesh = 0.16 mm ISO 3310-1 1 * 1 items
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COLUMN ORB SAX 80Å 10µM 4.6M 1 * 1 items
Supplier: WATERS
COLUMN ORB SAX 80Å 10µM 4.6M 1 * 1 items
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Total Rat Embryo RNA 1 * 200 µG
Supplier: Ambion
Total Rat Embryo RNA 1 * 200 µG
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Nitrile GL30cmTechniGlove TN1201W tacky Size S 1 * 1.000 items
Supplier: TECHNI GLOVE
Nitrile GL30cmTechniGlove TN1201W tacky Size S 1 * 1.000 items
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Pirani-Controller CVC 3000 Set with KF DN 16, for example for RE/RZ 2.5 and RE/RZ 6 with VSP 3000, Vacuum-Valve VV-B 15C, T-Connection, SW DN 15 and more connection parts 1 * 1 SET
Supplier: VACUUBRAND
Pirani-Controller CVC 3000 Set with KF DN 16, for example for RE/RZ 2.5 and RE/RZ 6 with VSP 3000, Vacuum-Valve VV-B 15C, T-Connection, SW DN 15 and more connection parts 1 * 1 SET
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VWR® pHenomenal® MU 6100 L Multi-Parameter Meter (pH/Conductivity/DO), Bench
Supplier: VWR Collection
User friendly instrument, with articulated electrode stand and IP 43-rated housing, provides high resolution and accuracy for precise multi-parameter measurements. This meter can either measure pH/mV and conductivity or pH/mV and oxygen simultaneously. Complete with USB output for connection to a computer. GLP compliant.
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BRASS MASS 10G WITH CERTIFICATE 1 * 1 items
Supplier: ZWIEBEL
BRASS MASS 10G WITH CERTIFICATE 1 * 1 items
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PISTON 0,5-10UL 1 * 1 items
Supplier: EPPENDORF
PISTON 0,5-10UL 1 * 1 items
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HEIZBAND SILIKON SIS10 1.5M 150W 1 * 1 ST
Supplier: ISOPAD
HEIZBAND SILIKON SIS10 1.5M 150W 1 * 1 ST
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VACUUM PIPETTE GREEN 1 * 1 items
Supplier: DELTALAB
VACUUM PIPETTE GREEN 1 * 1 items
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EZTEST STEAM G.STEAROTHERMOPHILUS 10.6 1 * 100 items
Supplier: MESA LABORATORIES
EZTEST STEAM G.STEAROTHERMOPHILUS 10.6 1 * 100 items
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CYCLOHEXIMIDE SOLUTION 10X10ML 1 * 100 mL
Supplier: Merck
CYCLOHEXIMIDE SOLUTION 10X10ML 1 * 100 mL
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TIP EJECTOR-PART 1 1 * 1 items
Supplier: Thermo Fisher Scientific
TIP EJECTOR-PART 1 1 * 1 items
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EZ PACKING SLEEVE 10MM 1 * 1 items
Supplier: OMNIFIT
EZ PACKING SLEEVE 10MM 1 * 1 items
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HPL Flat Base, 800mm wide 1 * 1 items
Supplier: BIGNEAT
HPL Flat Base, 800mm wide 1 * 1 items
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VIAL WITHOUT SNAPCAP 10ML 1 * 100 items
Supplier: Roth Carl
VIAL WITHOUT SNAPCAP 10ML 1 * 100 items
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Syringe 10Ul Rn 23Ga. 1 * 1 items
Supplier: Agilent
Syringe 10Ul Rn 23Ga. 1 * 1 items
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FLUORESCENT LAMP REPLACEMENT 1 * 1 items
Supplier: LABCONCO
FLUORESCENT LAMP REPLACEMENT 1 * 1 items
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Human Recombinant PDGF-AB
Supplier: STEMCELL Technologies
Platelet-derived growth factor (PDGF) is a dimeric glycoprotein consisting of two disulfide bridge-stabilized polypeptide chains, A and B, which are assembled as heterodimers (PDGF-AB) or homodimers (PDGF-AA and PDGF-BB) (Fretto et al.; Westermark and Heldin). PDGF signals through the receptor tyrosine kinases PDGFRalpha and PDGFRbeta. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin- like fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). It has been shown that PDGF-AB together with 5-Azacytidine (Catalog #72012), induces the conversion of mature bone and fat cells into tissue-regenerative multipotent stem cells (Chandrakanthan et al.).
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Test kit Alkalische phosphatase dgkc 10x20+2x30ml 1 * 1 KIT
Supplier: DIAGNOSTIC SYSTEMS DIASYS
Test kit Alkalische phosphatase dgkc 10x20+2x30ml 1 * 1 KIT
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O-RING 2,6 X 1,3 EPDM 1 * 1 items
Supplier: Thermo Fisher Scientific
O-RING 2,6 X 1,3 EPDM 1 * 1 items
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AutoCollect™ Specimen Collection Cards
Supplier: Ahlstrom-Munksjö
Ahlstrom AutoCollect™ specimen collection cards for high-throughput environments work efficiently in both DBS punch and direct elution. They are designed for microvolume sampling, transport and storage of dried blood spot (DBS) at ambient temperature.
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Precision therm., straight stem, -5+100:0,2C, capillary tube specially coated inside, with non-wetting blue special liquid, upper part 350x11mm, lower part 100x7-8mm, null
Supplier: Amarell
Precision therm., straight stem, -5+100:0,2C, capillary tube specially coated inside, with non-wetting blue special liquid, upper part 350x11mm, lower part 100x7-8mm, null
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BARREL ASSEMBLY 10µL 1 * 1 items
Supplier: Socorex Isba
BARREL ASSEMBLY 10µL 1 * 1 items
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ISOVERSINIC TUBING 12/17 ISO 1 * 1 m
Supplier: GERHARDT
ISOVERSINIC TUBING 12/17 ISO 1 * 1 m
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dNTPs for cDNA Probe Synthesis 1 * 300 µl
Supplier: Ambion
dNTPs for cDNA Probe Synthesis 1 * 300 µl
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10µl Pre-Sterilized Hamilton CO-RE Style Liquid Level Sensing Filter Tip. 96 Tips per Rack, 5 Racks/pack, 12 packs/case 1 * 5.760 items
Supplier: Corning
10µl Pre-Sterilized Hamilton CO-RE Style Liquid Level Sensing Filter Tip. 96 Tips per Rack, 5 Racks/pack, 12 packs/case 1 * 5.760 items
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MIKROZID AF WIPES JUMBO BOX (220PCS) 1 * 1 kg
Supplier: SCHUELKE MAYR
MIKROZID AF WIPES JUMBO BOX (220PCS) 1 * 1 kg