21409 Results for: "Simport+Scientific&pageNo=15"

Human Recombinant IL-15

Supplier: STEMCELL Technologies

Interleukin 15 (IL-15) is a four-alpha helix bundle cytokine with many similar properties to IL-2, with which it shares components of its receptor. The IL-15 receptor is a heterotrimeric receptor composed of IL-15Ra, the high-affinity receptor for IL-15, as well as IL-2/15Rb (CD122) and common gamma chain (CD132). IL-15 binds to IL-15Rα receptor and can then be presented in trans to IL-2/15Rb and common gamma chain on other cells. Trans-presentation is thought to be the major mechanism by which IL-15-mediated responses occur in mice, although may not be necessary in humans (Castillo et al.). The cytoplasmic domains of IL-2/15Rb and common gamma chain mediate signaling to activate JAK/STAT and PI3K pathways. IL-15 supports the survival and proliferation of naive CD4+ and CD8+ T cells, and promotes homeostasis of memory T cells. IL-15 also promotes the survival and differentiation of NK cells and regulates their cytolytic activity (Ma et al.).

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Non-ionic detergent, Kolliphor® HS 15

Supplier: Merck

Kolliphor HS 15 is a non-ionic detergent obtained by reacting 15 moles of ethylene oxide with 1 mole of 12-hydroxy stearic acid. It's a non-ionic solubiliser and emulsifier.

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Human IL-15 peptide

Supplier: ProSci Inc.

13 amino acid peptide near the center of human IL-15.

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VWR® VisiScope®, Eyepieces for Stereo Zoom Microscopes

Supplier: VWR Collection

Eyepieces, VWR® VisiScope®, 15× (15 mm)

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Human recombinant IL-15 R alpha & IL-15 fusion (from Cells)

Supplier: ProSci Inc.

Interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il15ra shares 45% amino acid sequence homology with the mouse form of the receptor. Eight isoforms of IL-15 R alpha mRNA have been identified, resulting from alternative splicing events involving different exons.Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs.

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2,4-Dinitroaniline 99% (dry weight) wetted with ca. 15% water

Supplier: Thermo Fisher Scientific

2,4-Dinitroaniline 99% wetted with ca. 15% water

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Indium ≥99.99% (metals basis), wire, Ø 1.5 mm (0.06 in)

Supplier: Thermo Fisher Scientific

Indium ≥99.99% (metals basis), wire, Ø 1.5 mm (0.06 in)

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Copper ≥99.9% (metals basis), wire, Ø 1.5 mm (0.06 in)

Supplier: Thermo Fisher Scientific

Copper ≥99.9% (metals basis), wire, Ø 1.5 mm (0.06 in)

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Graphite (natural) ≥99.9995% (metals basis), powder 2-15 µm

Supplier: Thermo Fisher Scientific

Graphite (natural) ≥99.9995% (metals basis), powder 2-15 µm

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Anti-Matrix Metalloproteinase 15, Prodomain Rabbit Polyclonal Antibody

Supplier: US Biological

Anti-Matrix Metalloproteinase 15, Prodomain Rabbit Polyclonal Antibody

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Anti-NOD2 Mouse Monoclonal Antibody [clone: NOD-15]

Supplier: US Biological

Anti-NOD2 Mouse Monoclonal Antibody [clone: NOD-15]

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Titanium(IV) ethanolate 85% tech. contains 5-15% isopropanol

Supplier: Thermo Fisher Scientific

Titanium(IV) ethanolate 85% tech. contains 5-15% isopropanol

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Anti-ACTB Mouse Monoclonal Antibody [clone: AC-15]

Supplier: US Biological

Anti-ACTB Mouse Monoclonal Antibody [clone: AC-15]

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Anti-CD14 Mouse Monoclonal Antibody [clone: MEM-15] (Biotin)

Supplier: Abcam

Biotin Mouse monoclonal [MEM-15] to CD14.

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Anti-SYT9 Mouse Monoclonal Antibody [clone: S276-15]

Supplier: US Biological

Anti-SYT9 Mouse Monoclonal Antibody [clone: S276-15]

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Anti-CD8A Mouse Monoclonal Antibody [clone: 15-11C5]

Supplier: US Biological

Anti-CD8A Mouse Monoclonal Antibody [clone: 15-11C5]

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Anti-TRPC5 Mouse Monoclonal Antibody [clone: S67-15]

Supplier: US Biological

Anti-TRPC5 Mouse Monoclonal Antibody [clone: S67-15]

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BROXO salt, granules 6 - 15 mm

Supplier: VWR Chemicals

Broxo water softener salt allows for problem free water softening that gives a great performance and is efficient in use. It is a very pure high-pressure compacted vacuum salt that dissolves evenly and gradually and is applicable to domestic and industrial installations. Broxo water softener can be used for both domestic and industrial use. The granules dissolves completely and evenly to leave no residual substances. The granules measure from 6mm up to 15mm and provide excellent performance. Also known as rock salt.