652 Results for: "Shenandoah Biotechnology"

Supplier: Shenandoah Biotechnology

Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bo ne marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. 1 * 2 µG

Supplier: Shenandoah Biotechnology

PRIME-XV Hematopoietic Cell Basal XSFM is an optimized xeno- and serum free media recommended for use in the expansion of human hem atopoietic cells, including hematopoietic progenitor cells. The performance of this medium was null

Supplier: Shenandoah Biotechnology

PRIME-XV T Cell CDM is the first commercially-available, chemically defined, animal component-free medium for the expansion and transduction of human T cells. The formulation is optimized to deliver consistently vigorous growth while maintaining T ce 1 * 1 L

Supplier: Shenandoah Biotechnology

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Lepti n acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. 1 * 5 µG

Supplier: Shenandoah Biotechnology

Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligan d signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Monocyte chemotactic protein 1 (MCP-1), also known as CCL2, is produced by injured or infected tissues. MCP-1 signals through the C CR2 and CCR4 G protein-coupled receptors to recruit memory T cells, monocytes, and dendritic cells to sites of inflamm 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferati on and megakaryocyte differentiation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Omentin is an adipokine that is produced and secreted by the small intestine, visceral adipose tissue, perivascular adipose tissue, and epicardial adipose tissue. Omentin enhances insulin-stimulated glucose uptake in adipocytes. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. kinases PDGFR-a an 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 20 (IL-20) is structurally related to interleukin 10 (IL-10) and is produced by keratinocytes and monocytes. IL-20 acts through the STAT3 signaling pathway to regulate the proliferation of keratinocytes during epidermal inflammation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. 1 * 5 µG

Supplier: Shenandoah Biotechnology

CD40 Ligand (CD40L), or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells, m onocytes, basophils, eosinophils, platelets, dendritic cells, and endothelial cells. 1 * 1 mg

Supplier: Shenandoah Biotechnology

Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelia l cells. IL-33 functions to induce type 2 cytokine production in polarized Type 2 T helper (Th2) cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Neurotrophin-4 (NT-4) is an important member of the nerve growth factor (NGF) family of proteins. Neurotrophins undergo paracrine a nd autocrine signaling to control neuronal survival, neuronal differentiation, and dendrite outgrowth. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF -A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

B cell-activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a type II member of the tumor necrosis factor (TNF) superfami ly. BAFF is expressed as a transmembrane protein on T cells, macrophages, and dendritic cells. 1 * 20 µG

Supplier: Shenandoah Biotechnology

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. 1 * 10 µG

Supplier: Shenandoah Biotechnology

PRIME-XV IS21 Supplement (50X) is a serum-free supplement optimized for use with PRIME-XV Neural Basal Medium to support maintenance and long- term culture of neuronal cells. This supplement is supplied as a 50X concentrated solution and should be di 1 * 10 mL

Supplier: Shenandoah Biotechnology

Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a c ritical role in the maintenance, survival, and differentiation of hematopoietic stem cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Receptor activator of nuclear factor kappa-B Ligand (RANKL) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANKL plays a critical role in bone metabolism and osteoclast differentiation. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 promotes al lergic reactions and inflammatory skin diseases. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF -A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Ciliary neurotrophic factor (CNTF) is a neurotrophic factor that promotes the survival of neuronal cell populations, neurite outgrow th, and neurotransmitter synthesis. CNTF also plays an important protective role during nervous system injury. 1 * 5 µG

Supplier: Shenandoah Biotechnology

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Lepti n acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. 1 * 5 mg

Supplier: Shenandoah Biotechnology

Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a c ritical role in the maintenance, survival, and differentiation of hematopoietic stem cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Monocyte chemotactic protein 3 (MCP-3), also called CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through th e G protein-coupled receptors CCR1, CCR2, and CCR3. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Growth hormone (GH) is an important mitogenic growth factor that is synthesized, stored, and secreted by somatotropic cells of the anterior pituitary gland. GH stimulates growth, cell reproduction, and cell regeneration. 1 * 1 mg

Supplier: Shenandoah Biotechnology

Ciliary neurotrophic factor (CNTF) is a neurotrophic factor that promotes the survival of neuronal cell populations, neurite outgrow th, and neurotransmitter synthesis. CNTF also plays an important protective role during nervous system injury. 1 * 500 µG