Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Roth Carl

SEKUROKA-UV-VOLLSICHTBRILLE ULTRAS. 1ST 1 * 1 ST

Supplier: Roth Carl

SEKUROKA-UV-VOLLSICHTBRILLE ULTRAS. 1ST 1 * 1 ST

Supplier: AAT BIOQUEST

Covidyte™ IF670 is a peptide substrate containing 12 amino acid sequence (VNSTLQSGLRKM) that can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide Quencher™ 5 (TQ5) as a quencher and iFluor® 670 as a fluorescent donor on the N-and C-terminals respectively where the fluorescence of iFluor® 670 is effectively quenched by TQ5 when the peptide is intact. When the peptide is hydrolyzed by coronavirus proteases, the iFluor® 670 fragment generates significantly enhanced fluorescence since its fluorescence is no longer quenched by TQ5. The activity of coronavirus proteases can be effectively monitored by the fluorescence intensity of iFluor® 670. Covidyte™ IF670 is a robust high throughput screening tool for searching inhibitors of coronavirus proteases. Comparing to the commonly used EDANS substrates (such as Covidyte™ ED450), the iFluor® 670 substrate has much stronger and longer fluorescence that is less interfered by coloured compounds that often cause false positive hits.

Supplier: FRISTADS KANSAS

Industrial jacket made of 65% polyester and 35% cotton, with soft nap on reverse side. The royal blue jacket is available with different accent and piping colours.

Supplier: RENTEX

Lab coats, Lab coats, Lab coats, TrenkaTex®, 52 (men), Cotton, Grey, For men, Baumwolle, Weight: 320 g/m², Industrial, General Purpose, Pockets: With pockets, Closure type: Press studs / snaps

Supplier: RENTEX

Vests made from stretch fabric, 60% polyester, 35% cotton and 5% DOW XLA.

Supplier: SIOEN

Protective, bicoloured jacket made of 100% soft double-sided polyester fleece providing good cold protection. With anti-pilling treatment and stitched seams. Can be zipped into the rain jacket 608Z.

Supplier: FRISTADS KANSAS

Shirt made of 100% spunbounded cotton (single jersey), with anti-pilling treatment. The grey melange version is manufactured from 85% cotton and 15% viscose.

Supplier: FRISTADS KANSAS

Industrial jacket made of 65% polyester and 35% cotton, with soft nap on reverse side. The navy blue jacket is available with different accent and piping colours.

Supplier: DGP INTELSIUS

ORCA Response is a multi-use, handheld, temperature-controlled packaging solution for transporting smaller payloads of red blood cells, platelets, pharmaceutical products and be easily carried and stored, making it the ideal solution for taking personal medicines on long journeys, including suitability as hand luggage on aeroplanes.

Supplier: TRENKA

This exclusive fine piqué polo shirt is made from 100% ring-spun combed cotton. The gray model is made from 90% preshrunk ring-spun combed cotton and 10% viscose.

Supplier: RENTEX

Bib and braces, Overall, bib and brace, Bib and braces, TrenkaTex®, 48 (men), Polyester/cotton, Hi-vis orange, For men, Polyester Baumwolle, Weight: 270 g/m², HiVis, General Purpose, Industrial, Pockets: With pockets

Supplier: RENTEX

Work shirt made of 60% cotton and 40% polyester, with 3M Scotchlite™ reflective materials.

Supplier: FRISTADS KANSAS

These bib and brace overalls are made of FAS® twill (100% cotton).

Supplier: FRISTADS KANSAS

Overalls made from 65% polyester and 35% cotton, with soft nap on reverse side.

Supplier: Corning

Manufactured from optically clear virgin polystyrene.

Supplier: COTTON CLASSICS HANDELS

Poloshirts, Poloshirt, Poloshirts, James & Nicholson, JN 26, XL, Polyester/cotton, Blue, For men, 60% ring-spun cotton and 40% polyester, Weight: 210 - 220 g/m², General Purpose, Pockets: With pockets, Closure type: Buttons

Supplier: RENTEX

Lab coats, Industrial coat, Lab coats, TrenkaTex®, 16 (ladies), Polyester/cotton, Grey, For ladies, 65% polyester and 35% cotton, Weight: 215 g/m², Industrial, Pockets: With pockets, Closure type: Press studs / snaps

Supplier: FRISTADS KANSAS

Cold resistant and water-repellent softshell jacket made of 100% windproof and breathable polyester stretch, Backing is made of 100% polyester microfleece. Reinforced with 100% polyamide.

Supplier: FRISTADS KANSAS

Classic style trousers made of 100% long staple FAS® cotton twill. Suitable for all kind of craftsmen. Pockets exposed to wear and tear are reinforced with 100% polyamide.

Supplier: RENTEX

Lab coats, Industrial coats, Lab coats, TrenkaTex®, 18 (ladies), Polyester/cotton, Blue, For ladies, 65% Polyester, 35% Baumwolle, Weight: 215 g/m², Pockets: With pockets, Closure type: Press studs / snaps

Supplier: RENTEX

Trousers, Trousers, Trousers, TrenkaTex®, 56 (men), Polyester/cotton, Hi-vis orange, For men, 60% cotton and 40% polyester, Weight: 270 g/m², HiVis, General Purpose, Industrial, Pockets: With pockets

Supplier: Rubbermaid Commercial Products

Safely collect waste wih touch-free closed lid containers.

Supplier: ProSci Inc.

PRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.

Supplier: MICRONOVA

The stainless steel Micronova BinLiner™ Stands™ are designed to work flawlessly with the BinLiners™ and similar sized bags. Securely hold a range of bin liner bags and feature two styles of open rod frames that allow ergonomic side removal of liners for simplified use.

Supplier: FRISTADS KANSAS

Work trousers made from 65% polyester and 35% cotton, in a luxury fabric. With rubber-free, elastic straps and adjustable waist.

Supplier: FRISTADS KANSAS

Work trousers made ​​of 65% polyester and 35% cotton. With mechanical stretch and brushed inside. Material and knee pad pockets reinforced with Cordura®.

Supplier: RENTEX

Trousers, Trousers, Trousers, TrenkaTex®, 48 (men), Polyester/cotton, Beige, For men, 60% polyester, 35% cotton and 5% DOW XLA, Weight: 285 g/m², General Purpose, Industrial, Pockets: With pockets, Closure type: Zip closure