20756 Results for: "Pentafluorophenyl+2-naphthalenesulphonate&pageNo=14&view=easy"

Supplier: Bioss

Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. GRB14 is a potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Supplier: Bioss

Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).

Supplier: Bioss

Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).

Supplier: Bioss

Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).

Supplier: Bioss

Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis (PubMed:24784001, PubMed:16648480). During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively (PubMed:16431929). Regulates cell growth through regulation of cell cycle progression and cytokinesis (PubMed:24854087). During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic process which controls CDKN1B degradation, resulting in positive regulation of cyclins, including CCNE1, CCND1 and CCNB1 (PubMed:24854087). During late neurogenesis, regulates the cerebellar, cerebral cortex and olfactory bulb development through regulation of apoptosis, cell proliferation and cell division (By similarity). Also is required for chromosome congression and alignment during mitotic cell cycle process (PubMed:15843429). Regulates cell spreading, focal adhesion dynamics, and cell migration through its interaction with RADIL resulting in regulation of RAP1A-mediated inside-out integrin activation by tethering RADIL on microtubules (PubMed:23209302).

Supplier: SIOEN

Multifunctional breathable jacket made of Siopor® Ultra (100% polyester fabric with 100% PU coating) that can be used in all weather conditions. The outer fabric is water-repellent and windproof while the coating on the inside is moisture attracting. With fixed lining, knitted wind cuffs in sleeves and taped seams.

Supplier: HUBER

Immersion thermostats are suitable for controlling the temperature of any bath, includes screw clamp allows the thermostats to be easily mounted on any vessels. All models are fitted with a powerful pressure/suction pump. Temperatures down to −30 °C can be achieved in combination with a refrigerated bath. A pump adapter for external temperature control and cooling coils for a cooling water connection are available as optional accessories.

Supplier: Greiner Bio-One

EDTA tubes are ideal for the examination of whole blood in haematology and are offered as either K2EDTA or K3EDTA tubes.

Supplier: Antibodies.com

Rat Galectin 7 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat Galectin 7 in serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Supplier: Antibodies.com

Human GPCR GPR14 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human GPCR GPR14 in tissue homogenates or other biological fluids.

Supplier: Antibodies.com

Rat CXCL14 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of rat CXCL14 in serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Supplier: Antibodies.com

Human P2Y14 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human P2Y14 in tissue homogenates, cell lysates or other biological fluids.

Supplier: Antibodies.com

Human CCL14 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human CCL14 in serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Supplier: FRISTADS KANSAS

These overalls with elasticated braces are made of different fabrics. The water-repellent fluorescent material in manufactured from 80% polyester and 20% cotton. The other parts are made of 65% polyester and 35% cotton which is slightly brushed on reverse. Reinforcements are made of 100% polyamide.

Supplier: Corning

Growth Factor Reduced (GFR) formulation is well suited for applications that require a more highly defined basement membrane preparation.

Supplier: Thermo Fisher Scientific

PS, NeutrAvidin™ coated plates for binding biotinylated antibodies or probes for ELISA and other target-specific assays.

Supplier: Antibodies.com

Human Galectin 7 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of human Galectin 7 in serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Supplier: Bioss

Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. May play a role in mediating insulin-stimulated ubiquitination of INSR, leading to proteasomal degradation. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2. GRB14 is a potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Supplier: HELLMA

Hellma® high precision quartz glass flow-through cells for absorption measurements in the UV/Vis range and/or fluorescence measurements, 0,1 to 50 mm path length, with inlet and outlet nozzle, or 2 screw connections and FEP tubes.

Supplier: HELLMA

Hellma® high precision macro cells from special optical glass for absorption measurements in the Vis range, 10 mm path length, with lid.

Supplier: ALSICO

Multirisk trousers especially designed for APC 2.

Supplier: Halyard

High quality gloves are designed to exact standards to meet the requirements of a contamination controlled environment.

Supplier: HELLMA

The Hellma® calibration standards comply with all necessary standards and regulations and thus offer the highest quality for recalibrating your spectrometer.

Supplier: Ansell

These overalls are made from a highly visible multi-layer fabric (external film barrier layer/non woven inner layer/core high barrier film layer) that is strong, durable and suitable for workers in extremely hazardous areas, including HAZMAT response teams.

Supplier: Ansell

These overalls are made from a highly breathable anti-static SMS fabric which utilises the latest developments in micro-fibre technology to ensure good filtration efficiency.

Supplier: FRISTADS KANSAS

These high visibility trousers are made of 54% modacrylic, 44% cotton and 2% anti-static fibre. Reinforced with 79% cotton FR, 20% polyamide, 1% anti-static fibre. They provide protection against chemicals, heat, flames and electric arcs.

Supplier: RENTEX

Chemical-resistant, flame-retardant jacket made from 54% modacrylic FR, 44% cotton and 2% conductive fibres. The material is anti-static and permanently flame retardant, and impregnated with water and oil repellent substances.

Supplier: Antibodies.com

Mouse CXCL14 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the in vitro quantitative determination of mouse CXCL14 in serum, plasma, tissue homogenates, cell lysates or other biological fluids.

Supplier: OHAUS

A range of four-place balances incorporate touch screen, advanced weighing and touch-free proximity sensor technologies. The easy to use control unit can be mounted on the base, above the base on an optional column, on a wall, or remotely (up to a distance of 3 metres with an optional cable). The touch screen display, with universal icons and informative prompts, simplifies set-up functions and basic operation. The operator has the added choice to assign the use of any of the four proximity sensors for hands-free operation of print, zero, tare, calibrate, automatic draft shield door (left or right) or draft shield light. The hands-free operation enables the user to minimise/eliminate any possible contamination of the control keypad - particularly important for weighing of sensitive materials. The balances have multiple application modes for basic weighing to SQC applications together with short stabilisation times and optimised performance specifications.

Supplier: ELMA SCHMIDBAUER

The Elmasonic EASY ultrasonic bath series includes 9 units of different sizes and is characterised by simple, user-friendly operation. With 100% ultrasonic power at a frequency of 37 kHz, the EASY solves cleaning tasks quickly and efficiently. Ideal for removing tenacious, mineral soiling and polishing pastes.