"Other Essentials"

Supplier: Abcam

Anti-CRBN antibody [EPR28739-64] is a Rabbit Monoclonal antibody that is used in CRBN Flow Cytometry (Intra), IP, Western Blot. Suitable for Human, Mouse samples. Cereblon (CRBN) is a multifunctional protein located in the cytoplasm, nucleus, and peripheral membranes of the human tissues. CRBN is closely related to the proliferation and metabolism of normal cells as well as tumor cells.It is part of the CRL4 CRBN ubiquitin E3 ligase complex, which is crucial for the action of immunomodulatory drugs (IMiDs) like lenalidomide and pomalidomide. These drugs bind to CRBN, leading to the degradation of transcription factors Ikaros and Aiolos, which are essential for myeloma cell survival. Additionally, novel cereblon E3 ligase modulators (CELMoDs) are being developed to overcome resistance to IMiDs, offering new therapeutic options for patients with CRBN mutation.

Supplier: Abcam

Anti-Fas antibody [EPR24898-74] is a Rabbit Monoclonal antibody that is used in Fas IHC-Fr, IHC-P, IP, Western Blot. Suitable for Mouse samples. FAS, also known as CD95 or APO-1, is a cell surface receptor that plays a significant role in regulating apoptosis (programmed cell death). FAS is crucial for inducing apoptosis in cancer cells. When FAS binds to its ligand (FASL), it triggers a cascade leading to cell death, which is essential for eliminating cancer cells.FAS was identified as an independent prognostic marker for recurrence free survival in breast cancer, with large variation in expression by receptor subtypes. Interestingly, the prognostic effect of CD8+ TILs in ER-negative disease was only valid for tumors with a high FAS expression.FAS expression might therefore act as a predictive factor for new emerging therapies.Researchers are exploring ways to enhance FAS signaling to prevent cancer relapse and improve the durability of immunotherapy responses.

Supplier: VWR Collection

PFAS PP short thread caps or PE snap ring caps, light green, with hole. White silicone/transparent polypropylene, for PFAS analysis.

Supplier: Abcam

Mouse Monoclonal CD18 antibody. Low endotoxin, Azide free. Suitable for IP, Flow Cyt, WB, FuncS and reacts with Human samples. Immunogen corresponding to Cell preparation containing ITGB2 protein.

Supplier: TEMPSHIELD

Waterproof Cryo-Grip® gloves offer improved grip on small objects while protecting hands and arms when working in hasardous, ultra-cold environments.

Supplier: TEMPSHIELD

Hand protection for industrial settings working with LNG or liquid nitrogen.

Supplier: Abcam

The DNA Concentrator Kit (ab156895) is a complete set of essential components which enables the experimenter to efficiently concentrate DNA from various DNA samples with low concentration of DNA including those from microdissection samples and paraffin-embedded tissues.

Supplier: Abcam

The DNA Isolation Kit-Urine (ab156899) is a complete set of essential components which enables the experimenter to efficiently isolate DNA from urine.

Supplier: THERMO SAVANT

The Thermo Scientific™ Savant™ SpeedVac™ SPD130DLX vacuum concentrator is a medium-capacity, vacuum concentrator with a modular design. It is compatible with a wide variety of solvents and offers resistance to TFA, DMSO, and other aggressive solvents used in combinatorial chemistry applications.

Supplier: Abcam

The PCR Clean-up Kit (ab156894) is a complete set of essential components which enables the experimenter to efficiently clean-up PCR products from various sources including conventional or real time thermal cycling PCR and isothermal gene amplification (PCR).

Supplier: ROBU GLASFILTER

ROBU® gas washing bottle with large VitraPOR® filter disc and NS 29/32 or NS 45/40 standard joint ensures efficient gas absorption in laboratory applications.

Supplier: VWR Collection

Designed for for PFAS analysis, these kits contain 0,7 ml polypropylene snap ring vials with silicone white/polypropylene transparent septum, available with or without slit.

Supplier: Cytiva

illustra™ AutoSeq™ G-50 columns are specifically designed to remove fluorescent dye-terminators from sequencing reactions prior to analysis on automated sequencers. Effective purification is essential for high quality sequencing results since residual dye-terminators can obscure data. illustra™ AutoSeq™ G-50 consists of MicroSpin™ columns containing Sephadex™ G-50, pre-equilibrated in double-distilled water. This is important because even the small amount of salt in traditional buffers (such as TE buffer) can cause electrophoretic artifacts on salt-sensitive automated sequencers.

Supplier: VWR Collection

PFAS stands for per- and polyfluoroalkyl substances, and are colloquially known as ‘forever chemicals’. Available with or without a pre-slit septum.

Supplier: VWR Collection

PFAS stands for per- and polyfluoroalkyl substances, and are colloquially known as ‘forever chemicals’. Available with or without a pre-slit septum.

Supplier: VWR Collection

Vials, PP, 1,5 ml with 9 mm Short thread cap, Silicone/Polypropylene.