136747 Results for: "Microscopy+Buffers&pageNo=24"

Supplier: SONTARA

Sontara® Cleanroom wipes are specially designed for the challenging task of cleaning a cleanroom - ideal for electronic manufacturing, pharmaceutical, biotechnology applications and surface mount technology. These micro-level cleaning fabrics are 'virtually' lint-free and naturally absorbent, without binders or other additives.

Supplier: RAININ

This light-weight, ergonomically shaped pipette with fingerhook is ideal for dispensing large number of samples or reagents with dedicated volumes.

Supplier: IDEX RHEODYNE

Sample loop, PEEK, 20 ml, For tube I-Ø: 2,0 mm, For tube O-Ø: 3 mm

Supplier: STEMCELL Technologies

Fibroblast growth factor 21 (FGF-21) is a member of the FGF family. Using β-Klotho as a cofactor, FGF-21 signals through FGF receptor 1c and 4 to activate PI3K and MAPK pathways (Mattila and Härkönen; Kharitonenkov et al.). FGF-21 expression is regulated by tissue-specific peroxisome proliferator-activated receptors (PPARs). Upon PPAR-α stimulation FGF-21 is produced in the liver, and activation of PPAR-γ leads to FGF-21 production in adipose tissue. FGF-21 promotes insulin-independent glucose uptake and lipid accumulation in primary human adipocytes and in mouse 3T3-L1 cells. In pancreatic islets and INS-1 cells it inhibits glucose-mediated glucagon release and stimulates insulin production. FGF-21 does not induce proliferation in immortalized cell lines, unlike other FGFs (Kharitonenkov and Shanafelt). FGF-21 regulates thermogenesis in white and brown adipose tissue, and metabolic processes in cells of pancreatic origin (Kharitonenkov et al.).

Supplier: Restek

Prepared from an equal-volume blend of 5W30, 10W30, 10W40, and 20W50 motor oils. After blending, a precisely weighed amount of the composite is added to a volumetric flask to produce the standard.
Motor Oil standards may exhibit lot-to-lot variation.

Supplier: Thermo Scientific

trans-2,6-Dichloro-β-nitrostyrene

Supplier: Thermo Scientific

1H-1,2,4-Triazole-3-thiol

Supplier: Thermo Scientific

Methyl-2,6-dichloro-5-fluoronicotinate

Supplier: Merck

1,4-Dichlorophthalazine, Sigma-Aldrich®

Supplier: Thermo Scientific

2,6-Bis(hydroxymethyl)-p-cresol

Supplier: Merck

2,3-Lutidine, Sigma-Aldrich®

Supplier: Merck

2,3-Difluoroaniline, Sigma-Aldrich®

Supplier: Merck

2,6-Diaminopyridine, Sigma-Aldrich®

Supplier: Merck

2,3-Dichlorobenzaldehyde, Sigma-Aldrich®

Supplier: LGC Standards PROMOCHEM

2,2',5-Trichlorobiphenyl (PCB No. 18)

Supplier: LGC Standards PROMOCHEM

2,3',6-Trichlorobiphenyl (PCB No. 27)

Supplier: Merck

1,4-Diiodobenzene, Sigma-Aldrich®

Supplier: Merck

2,6-Diaminotoluene, Sigma-Aldrich®

Supplier: Merck

2,6-Dinitrobenzaldehyde, Sigma-Aldrich®

Supplier: Molekula

trans-1,4-Dichloro-2-butene

Supplier: CELLPATH

21 compartments for 76×26, 50×76 and 76×76 mm slides or 35 mm transparencies with hanging system for storage in conventional filing cabinet.

Supplier: Thermo Scientific

3-Bromo-2,6-dihydroxy-5-nitrobenzonitrile

Supplier: AccuStandard

2,6-Dichlorobiphenyl (PCB No. 10)

Supplier: Merck

1,4-Diethylbenzene, Sigma-Aldrich®

Supplier: Merck

2,6-Diisopropylaniline, Sigma-Aldrich®

Supplier: Molekula

2,4,5-Trifluoro-3-methoxybenzoic acid

Supplier: Merck

2,5-Dimethylpyrrole, Sigma-Aldrich®

Supplier: Merck

1,4-Dibenzoylbenzene, Sigma-Aldrich®

Supplier: Thermo Scientific

2,5-Dimethyl-1,3,4-thiadiazole

Supplier: STEMCELL Technologies

Interleukin 21 (IL-21) is a pleiotropic cytokine that is composed of four α-helical bundles and primarily produced by natural killer T (NKT) cells, T follicular helper (Tfh) cells, and Th17 cells (Spolski and Leonard 2008). IL-21 signals via receptor heterodimerization of IL-21 receptor and IL-2 receptor subunit gamma (IL-2RG or CD132), both of which have a common gamma-chain subunit and activate the JAK/STAT, MAPK, and PI3K pathways (Parrish-Novak et al.; Ozaki et al. 2000; Spolski and Leonard 2014). IL-21 has been shown to have a critical role in regulating immunoglobulin production and differentiation of the pro-inflammatory Th17 population of cells (Ozaki et al. 2002; Nurieva et al.). Additionally, IL-21 specifically sustains CD8+ T cell effector activity and provides a mechanism of CD4+ T cell help during chronic viral infection (Elsaesser et al.). IL-21 signaling was also found critical for the development of type 1 diabetes in non-obese diabetic (NOD) mice (Sutherland et al.) and control of T cell autoimmunity by regulatory B cells (Yoshizaki et al.).