106118 Results for: "Laboratory+Software&pageNo=25"

Supplier: VARIAN

GC Column 50% Phenol 1 * 1 items

Supplier: MP Biomedicals

CYSTAMINE

Supplier: ProSci Inc.

Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.

Supplier: Mettler - Toledo

A range of high performance microbalances with the XP interface that delivers levels of control and safety that are required for regulated environments.

Supplier: Corning

Corning® Nu-Serum™ growth media supplement provides a low-protein alternative to newborn calf, foetal bovine, and other sera routinely used for cell culture. The low-protein content facilitates protein purification, virus production, monoclonal antibody production and screening, and increases the frequency of successful transfection of cells.

Supplier: MP Biomedicals

Storage: Room Temperature
Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds, it is a strong chaotropic agent. Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a free flowing powder with solid material dispersed throughout, or a solid. The quality of the product does not appear to be affected and solutions prepared from the free-flowing and lumpy guanidine HCl appear identical.
Guanidine hydrochloride can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA. Guanidine hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of protein, it can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins.

Supplier: TRANE TECHNOLOGIES

Eliminate uncertainty in your freeze-thaw processes. Purpose-built for bio-processing applications, the Controlled Rate Chamber Model 4000 offers uniformity and repeatability in rapid, controlled freezing and thawing applications. The forced air convection cooling rapidly freezes material from ambient to −80 °C.

Supplier: Thermo Fisher Scientific

Ammonium iron(II) sulphate hexahydrate ≥99.999% (metals basis), Puratronic®

Supplier: MP Biomedicals

2,3,5-Triphenyltetrazolium Chloride is a redox indicator. In the TTC assay (also known as TTC test or tetrazolium test), TTC is used to differentiate between metabolically active and inactive tissues. The white compound is enzymatically reduced to red TPF (1,3,5-triphenylformazan) in living tissues due to the activity of various dehydrogenases (enzymes important in oxidation of organic compounds and thus cellular metabolism), while it remains as white TTC in areas of necrosis since these enzymes have been either denatured or degraded.
2,3,5-Triphenyltetrazolium Chloride is commonly used in biochemical experiments especially to indicate cellular respiration. TTC has been employed in autopsy pathology to assist identification of post-mortem myocardial infarctions. Healthy viable heart muscle will stain deep red from the cardiac lactate dehydrogenase; while areas of potential infarctions will be more pale. Useful indicator for reducing substances

Supplier: FRISTADS KANSAS

Thanks to its durability and high degree of comfort, the PR54 jacket is perfectly suited to workshops and industrial and service enterprises. The material is made from 65% polyester and 35% cotton. The inside is brushed and as a result conveys a pleasantly comfortably cotton feeling. The outside is also resistant to the roughest demands and will not fade even after countless washes.

Supplier: ProSci Inc.

Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and Natural Killer (NK) cells. Some of these IL-12 activities include the induction of IFN-gamma and TNF in resting and activated T and NK cells; the enhancement of cytotoxic activity of resting NK and T cells, the stimulation of resting T cell proliferation in the presence of a comitogen; and the enhancement of NK cell proliferation. Current evidence indicates that IL-12 is a key mediator of cellular immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular immunity and as an antitumour and anti viral agent.

Supplier: Mettler - Toledo

Combined glass pH electrodes for direct pH measurement and acid/base titrations in aqueous or non-aqueous media. The all-rounder for a large variety of uncritical applications in almost all kinds of industries: Acid content of beverages, acid and base capacity of water samples, pH start applications.

Supplier: Thermo Fisher Scientific

SOLA™μ 96 well SPE micro elution plates are specifically designed to meet the increasingly demanding challenges found within bioanalysis. The micro elution format is uniquely positioned to deliver on bioanalytical needs, but limitations with existing
technological design has prevented significant uptake. The SOLA™μ product eliminates these issues by utilising SOLA technology, which removes the need for frits to retain the sorbent material and, in combination with a macro porous structure, allows for a robust, easily controllable platform for reproducible processing of bioanalytical samples.

Supplier: MP Biomedicals

Paromomycin is a broad spectrum aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus. It has in vitro and in vivo activity similar to neomycin. It is effective against gram-negative bacteria, gram-positive bacteria, some protozoan species, and limited anti helminth. It is used to study bacterial protein synthesis at the level of 16S ribosomal RNA and 30S ribosome assembly. Paromomycin is used to study cytosine-cytosine (CC) mismatch-containing RNA molecules and is used to inhibit cryptosporidium infection of a human enterocyte cell line.

Supplier: CONTEC

Contec® Sterile IPA is a blend of 70% v/v Isopropanol with 30% water for injection or purified water, this ready to use formulation eliminates mixing, filtration, processing and QC expense of in-house production. Used for wiping gloved hands and also as surface cleaner for removal of contaminants particularly when used in conjunction with Contec® sterile wipes.

Supplier: Avantor

Suitable for use on third party robotic instruments Hamilton Microlab Star and Nimbus. Available in conductive version, with or without filter, and in CE-IVD marked version for clinical diagnostic applications.

Supplier: G-Biosciences

Kanamycin Monosulfate null

Supplier: FRISTADS KANSAS

Thanks to its durability and high degree of comfort, the PR54 jacket is perfectly suited to workshops and industrial and service enterprises. The material is made from 65% polyester and 35% cotton. The inside is brushed and as a result conveys a pleasantly comfortably cotton feeling. The outside is also resistant to the roughest demands and will not fade even after countless washes.

Supplier: Spectrum Chemical

BSE/TSE statement (available upon request)
Allergen statement (available upon request)

Supplier: ProSci Inc.

Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have multiple effects on T cells and Natural Killer (NK) cells. Some of these IL-12 activities include the induction of IFN-gamma and TNF in resting and activated T and NK cells; the enhancement of cytotoxic activity of resting NK and T cells, the stimulation of resting T cell proliferation in the presence of a comitogen; and the enhancement of NK cell proliferation. Current evidence indicates that IL-12 is a key mediator of cellular immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been suggested that IL-12 may have therapeutic potential as a vaccine adjuvant that promotes cellular immunity and as an antitumour and anti viral agent.

Supplier: ProSci Inc.

The protein encoded by the KIF25 gene is a member of the kinesin-like protein family. Protein family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. However, the particular function of this gene product has not yet been determined. Two alternatively spliced transcript variants which encode products have been described. Other splice variants have been found that lack exon 2 and the initiation codon for translation. The protein encoded by this gene is a member of the kinesin-like protein family. Protein family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. However, the particular function of this gene product has not yet been determined. Two alternatively spliced transcript variants which encode products have been described. Other splice variants have been found that lack exon 2 and the initiation codon for translation.

Supplier: RENTEX

Flame retardant trousers made of 54% modacrylic FR, 44% cotton and 2% guides. The material is permanently flame retardant, anti-static and impregnated to be water and oil repellent. Skin-friendly due to high cotton content.

Supplier: Roth Carl

PIPES monosodium salt

Supplier: Thermo Fisher Scientific

Hypercarb porous graphitic carbon (PGC, Hypercarb) is a unique stationary phase composed of flat sheets of hexagonally arranged carbon atoms with a satisfied valence, as in a very large polynuclear aromatic molecule, it provides extended separation capabilities, enhanced retention of polar compounds and separtion of structurally related analytes with stability at extreme pH and high temperature.

Supplier: Thermo Scientific

Thermo Scientific™ TDE Series ultra-low temperature chest freezers set the standard for performance and reliable sample storage in heavy use situations. A sustainable solution with ultimate sample security and operational savings for every laboratory.

Supplier: IKA

The viscosity of most liquids depends on the temperature. To obtain reliable measurement results, accurate temperature control is crucial. The CBC ROTAVISC SBS me-vi Package is the perfect solution for precise viscosity measurement of temperature-dependent samples in the laboratory.

Supplier: Apollo Scientific

4-Nitrophenyl phosphate disodium salt hexahydrate (pNPP)

Supplier: IKA

Compact incubator shakers designed for safe, unattended operation in a temperature controlled environment. The units have a large LED display for speed, temperature and timer. An integrated PID temperature control allows the use of PT1000 temperature sensors to ensure highly accurate temperature control. The electronically controlled incubators come equipped with RS232 and USB ports for PC interface. All functions can be controlled and documented using optional labworldsoft® software. In addition the  KS 3000 ic control has a built in cooling coil for connection to an external cooling unit.

Supplier: SHP Steriltechnik

ZB Motor 35-100 l 1 * 1 items

Supplier: VARIAN

CP-Sil 5CB-MS GCMS Column, 30m*0.25mm*0.25um 1 * 1 items