112282 Results for: "Glassware+Washing+Machines&pageNo=10&view=easy"

Supplier: Portwest

The DX4 winter jacket uses dynamic stretch and highly insulating fabric that guarantees warmth and comfort. The ergonomic profile and raglan sleeves allow for an unrestricted range of motion and greater freedom of movement. Its longer back length, wind cuffs, and adjustable hood provide extra protection against the elements.

Supplier: Portwest

Contemporary work trouser made from highly durable ripstop fabric that stretches as you move. Subtle articulation on the knees allow for increased freedom of movement and a high rise back waistband ensures protection in all working positions. Packed with functionality including pre-bent knees, a crotch gusset, two tier knee pad pockets and an adjustable leg length for added convenience.

Supplier: STEMCELL Technologies

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang et al.; Dorssers et al.; Broughton et al.). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton et al.). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock et al.). This product is animal component-free.

Supplier: Restek

[EN]RXI-LAO COLUMN 40 MX0.18MM IDX1.0µM 1 * 1 ST

Supplier: EPPENDORF

Unleash the power of precision in DNA research with Eppendorf® DNA LoBind® tubes. Engineered with proprietary LoBind® technology, these microcentrifuge tubes redefine sample handling, minimising the risk of loss and maximising DNA recovery. Ideal for low-concentration applications, including PCR, qPCR, and DNA sequencing, these tubes ensure accuracy, purity, and optimal yields.

Supplier: EPPENDORF

Eppendorf's twin.tec® 96-well, 150 µl PCR Plates feature a polycarbonate frame and thin-walled polypropylene wells ensuring optimal heat transfer and high rigidity. The SafeCode variants enhance sample identification, while the BioBased options, manufactured using renewable resources, provide an eco-friendly alternative without compromising performance.

Supplier: STEMCELL Technologies

Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine that activates NF-kB, MAPK, and PI3K/AKT pathways. Activated T cells and macrophages are the primary producers of TNF-α in response to inflammation and infectious conditions. Many other cell types have been shown to produce TNF-α, among them B cells, NK cells, mast cells, neutrophils, dendritic cells, microglia, endothelial cells, smooth muscle cells, cardiomyocytes, and fibroblasts. TNF-α has cytotoxic effects on cancer cells in vitro by stimulating anti-tumor immuno- suppressive responses. TNF-α stimulates expression of E- and P-selectins, thus facilitating adhesion of neutrophils, monocytes, and memory T cells to activated platelets and endothelial cells (Zelová and Hosek). Other effects of TNF-α include vasodilatation and edema formation. This product is animal component-free.

Supplier: IKA

The IC immersion circulators have an extended temperature range for tempering fluids in open and covered water baths up to 200/250 °C. The LED/ graphic TFT Display illustrates all relevant process parameters. Units feature push and turn buttons for intuitive menu navigation. IC immersion circulators ensure short heating up times and have a temperature stability of ±0,01/0,02 K (basic/control model). Both models feature optical and acoustic safety warnings, an adjustable safety circuit, a powerful pressure/suction pump and can be used for internal and external applications.

Supplier: STEMCELL Technologies

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including mast cells, basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Fung et al.; Metcalf et al.; Broughton et al.). IL-3 is produced by activated T cells, and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by mast cells, basophils and eosinophils. The mouse IL-3 receptor consists of a unique alpha-subunit (CD123) and two beta subunits, one specific for IL-3 (βIL-3), the other shared with the receptors for IL-5 and GM-CSF (beta common chain, βc or CD131). IL-3 binding to heterodimeric receptors containing the alpha subunit and one of either beta subunits activates JAK/STAT, MAPK, and PI3K signaling pathways (Scott and Begley).

Supplier: ProSci Inc.

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulphide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important homeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens. IL-2 promotes T cell proliferation and particularly naive T cells. IL-2 signalling on activated T cells is effected through a quaternary high-affinity receptor complex consisting of IL-2, IL-2Ralpha (CD25), IL-2Rbeta and IL-2Rgamma. Naive T cells are relatively insensitive to IL-2 as they only express small amounts of IL-2Rbeta and IL-2Rgamma. They only acquire sensitivity after CD25 expression, which captures the cytokine and presents it to the IL-2Rbeta and IL-2Rgamma receptors. IL-2 Superkine (Fc) is an artificial variant of IL-2 containing mutations at positions L80F / R81D / L85V / I 86V / I92F. These mutations are located in the molecule's core that acts to stabilize the structure and to give it a receptor-binding conformation mimicking native IL-2 bound to CD25. These mutations effectively eliminate the functional requirement of IL-2 for CD25 expression and elicit proliferation of T cells. Compared to IL-2, the IL-2 superkine induces superior expansion of cytotoxic T cells, leading to improved antitumor responses in vivo, and elicits proportionally less toxicity by lowering the expansion of Tregulatory cells and reducing pulmonary oedema.

Supplier: ProSci Inc.

Receptors for the Fc region of immunoglobin G (Fc gamma R) are divided into three classes and Fc gamma RIII is a multifunctional, low/intermediate affinity receptor. In humans, Fc gamma RIII is expressed as two distinct forms (Fc gamma RIIIA and Fc gamma RIIIB) that are encoded by two different but highly homologous genes in a cell type-specific manner. Fc gamma RIIIB is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas Fc gamma RIIIA is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages. The Fc gamma RIIIA receptor is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), mast cell degranulation, and clearance of immune complexes. Fc gamma RIIIA has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and delivers an activation signal in the immune responses. Aberrant expression or mutations in this gene is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. In humans, it is a 50 -70 kD type I transmembrane activating receptor. The Fc gamma RIIIA cDNA encodes 254 amino acid including a 16aa signal sequence, 191 amino acid ECD with two C2-type Ig-like domains, five potential N-glycosylation sites, a 22 amino acid transmembrane sequence and a 25 amino acid cytoplasmic domain.

Supplier: Portwest

A highly innovative and functional jacket that provides seven wearer combinations. This extremely versatile jacket is highly adaptable to all weather conditions and is certified to the highest in waterproof and breathable standards.

Supplier: Thermo Fisher Scientific

For customers in cell and gene therapy and vaccine production, the CryoMed with OPC UA provides precise, repeatable freezing results that protect samples from intracellular freezing. The CryoMed features OPC UA serial communication (ethernet) capabilities, comes standard factory certifications, provides enhanced data traceability via a touch screen user interface and offers customizable freezing profiles while supporting 21 CFR part 11 and GMP needs.

Supplier: STEMCELL Technologies

Receptor activator of nuclear factor kappa-B ligand (RANKL) is a member of the tumor necrosis factor (TNF) superfamily (Anderson et al.). Cytokines in the TNF superfamily are involved in a variety of long-term cellular activities such as differentiation, proliferation, and cell death (MacEwan). RANKL is a type II homotrimeric transmembrane protein expressed in both a membrane-bound and secreted form (Ikeda et al.). RANKL binds to the receptor activator of nuclear factor kappa-B (RANK). Upon binding to its receptor, RANKL activates the AKT signaling pathway (Moon et al.). Osteoprotegerin (OPG) may also bind RANKL, and this binding competes with RANKL-RANK binding (Lacey et al.). RANKL is involved in osteoclastogenesis (Lacey et al.; Yasuda et al.) and T cell activation (Wong et al.). This product is animal component-free.

Supplier: Merck

L-Arginine hydrochloride, Sigma-Aldrich®

Supplier: EPPENDORF

Eppendorf Fast PCR tube strips made of polyethylene transfer heat faster than tubes made of traditional plastics. The Fast PCR tube strips are particularly suited to scientists using Fast PCR reagent kits, scientists trying to speed up protocols or cyclers with high heating and cooling rates.

Supplier: ProSci Inc.

F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Supplier: Sartorius

It is compact, environmentally friendly, reliable and easy-to-use. arium® comfort I produces ASTM Type 1 ultrapure water and Type 3 pure water. The system contains state of the art reverse osmosis technology and a unique cartridge. arium® comfort I optimizes water consumption using the integrated iJust control unit. Applied for HPLC, GC-MS, AAS, ICP-MS, Ion chromatography, TOC-Analysis, photometry and for buffer solutions.

Supplier: STEMCELL Technologies

Fibroblast growth factor 7 (FGF-7) is a member of the FGF family, and acts exclusively through a subset of FGF receptor isoforms expressed predominantly by epithelial cells (Finch and Rubin). FGF-7 seems to act specifically on epithelial cells and stimulates proliferation, migration, and differentiation of these cells, and also participates in epithelial protection and repair both in vitro and in vivo (Finch and Rubin; Werner). In contrast, FGF-7 is produced solely by cells of mesenchymal origin, and functions as a paracrine mediator of mesenchymal-epithelial communication (Rubin et al.). FGF-7 has also been shown to supplement several wound-healing properties of bioengineered skin (Erdag et al.) and to induce autophagy in human keratinocytes (Belleudi et al.). Additionally, FGF-7 has a role in pluripotent stem cell differentiation to endodermal pancreatic-like insulin-producing cells and thymic epithelial cells (Inami et al.; Niu et al.).

Supplier: Amarell

Hydrometer, DIN 12791/similar to BS 718, L20, 0,9000-0,9200:0,0002g/cm , ref. temp. 20C, without therm., 430mm long, suitable for g overnment verification 1 * 1 items

Supplier: MACHEREY-NAGEL

TLC precoated plates CEL 300-25 size: 10x20 cm pack of 50 1 * 50 items

Supplier: BUCHI

Funnel for small vessels 1 * 1 items

Supplier: Testo

HPA 1 * 1 items

Supplier: Merck

FREUND'S ADJUVANT INCOMPLETE 1 * 1 Each

Supplier: Roth Carl

THERMOMETER P300 1 * 1 items

Supplier: Honeywell Safety

SLEEVES HYPALON 1 * 1 items

Supplier: CHRIST MARTIN

[EN]RACK INCL 5 SHELVES Ø200MM + LYOBUS 1 * 1 ST

Supplier: VACUUBRAND

HOSE NOZZLE NW10 1 * 1 items

Supplier: MACHEREY-NAGEL

NucleoSpin RNA Plant and Fungi (50) 50 preps for the isolation of RNA from plant and fungi - NucleoSpin RNA Plant Columns, NucleoSpi n Plant Filters, Collection Tubes, buffers no dangerous goods according transport regulations 1 * 50 items

Supplier: Showa

SHOWA CS720 full nitrile coated chemical protective glove Type A with rough finish extra coating on hand on seamless PEster/nylon liner Contact heat resistance level 1 size 11/XXL 1 * 60 PAIR