6393 Results for: "Gas+Tubes&pageNo=39"

Supplier: Bioss

Mouse protein 25 alpha (MO25 alpha, CAB39) is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity. Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK). The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle; however, LKB1-STRAD-MO25 activity is not increased by muscle contraction. This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms.

Supplier: Bioss

Mouse protein 25 alpha (MO25 alpha, CAB39) is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity. Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK). The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle; however, LKB1-STRAD-MO25 activity is not increased by muscle contraction. This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms.

Supplier: Bioss

Mouse protein 25 alpha (MO25 alpha, CAB39) is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity. Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK). The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle; however, LKB1-STRAD-MO25 activity is not increased by muscle contraction. This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms.

Supplier: Sartorius Balances

Quintix® Pro laboratory balances are not just about meeting your expectations but exceeding them. The balances have an array of premium features that enhance usability, flexibility, and incorporate an eco-friendly design.

Supplier: FRISTADS KANSAS

Overalls made from 65% polyester and 35% cotton, with soft nap on reverse side.

Supplier: Corning

Manufactured from optically clear virgin polystyrene.

Supplier: FRISTADS KANSAS

Industrial jacket made of 65% polyester and 35% cotton, with soft nap on reverse side. The navy blue jacket is available with different accent and piping colours.

Supplier: RENTEX

Work shirt made of 60% cotton and 40% polyester, with 3M Scotchlite™ reflective materials.

Supplier: Sartorius Balances

The Cubis® II laboratory balances are modular, therefore they allow to choose between applications and configurations which suit the best to the needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions.

Supplier: Brady

Self-laminating vinyl (B-427) is an excellent material for wire and cable identification. This material has good clarity and conformability, and is self-extinguishing.

Supplier: Bioss

Mouse protein 25 alpha (MO25 alpha, CAB39) is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity. Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK). The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle; however, LKB1-STRAD-MO25 activity is not increased by muscle contraction. This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms.

Supplier: NEW PIG

This compact "Green" bag makes transport simple, and its recycled-content pads and socks soak up more liquid with less environmental impact.

Supplier: FRISTADS KANSAS

Industrial jacket made of 65% polyester and 35% cotton, with soft nap on reverse side. The royal blue jacket is available with different accent and piping colours.

Supplier: RENTEX

Vests made from stretch fabric, 60% polyester, 35% cotton and 5% DOW XLA.

Supplier: Sartorius Balances

The Cubis® II laboratory balances are modular, therefore they allow to choose between applications and configurations which suit the best to the needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions.

Supplier: Portwest

This flame-retardant boilersuit is most suitable for use within the welding industry, with excellent protection for workers who are exposed to extreme heats. Made of Bizweld 330 fabric (100% cotton drill).

Supplier: RENTEX

Lab coats, Industrial coats, Lab coats, TrenkaTex®, 20 (ladies), Polyester/cotton, Blue, For ladies, 65% polyester and 35% cotton, Weight: 215 g/m², Industrial, Pockets: With pockets, Closure type: Press studs / snaps

Supplier: ProSci Inc.

bHLH proteins are essential for neurogenesis, myogenesis, hematopoiesis and sex determination. HES1 (Hairy and Enhancer of Split 1) is a basic Helix-Loop-Helix (bHLH) transcriptional repressor regulated by the Notch pathway and expressed in various tissues. HES1 is well known in development of different tissues, particularly endoderm derived endocrine organs like pancreas and neuroendocrine cells of lung. HES1 controls normal development by regulating proliferation and differentiation and so cell fate. Notch signalling plays both oncogenic and tumour suppressor roles depending on cell type. In contrast to T cell acute lymphoblastic leukaemia (ALL), where Notch activation promotes leukemogenesis, induction of Notch signalling in B cell ALL (B-ALL) leads to growth arrest and apoptosis. The Notch target HES1 is sufficient to reproduce this tumour suppressor phenotype in B-ALL by interacting and activating PARP-1 and regulating proapoptotic signals.

Supplier: NEW PIG

Stop the spread of acids and caustics with these specially treated socks. Ideal for highly concentrated corrosives.

Supplier: FRISTADS KANSAS

Work overalls made from 65% polyester and 35% cotton. With napped inner.

Supplier: RENTEX

Trousers, Trousers, Trousers, TrenkaTex®, 42 (men), Polyester/cotton, Grey, For men, Canvas, 65% Polyester und 35% Baumwolle, Weight: 310 g/m², General Purpose, Industrial, Pockets: With pockets, Closure type: Buttons

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

Supplier: GA

Cryogenic direct thermal labels intended for labeling already frozen surfaces and containers under deep-freeze conditions, as low as (–80 °C).

Supplier: ProSci Inc.

bHLH proteins are essential for neurogenesis, myogenesis, haematopoiesis and sex determination. HES1 (Hairy and Enhancer of Split 1) is a basic Helix-Loop-Helix (bHLH) transcriptional repressor regulated by the Notch pathway and expressed in various tissues. HES1 is well known in development of different tissues, particularly endoderm derived endocrine organs like pancreas and neuroendocrine cells of lung. HES1 controls normal development by regulating proliferation and differentiation and so cell fate. Notch signalling plays both oncogenic and tumour suppressor roles depending on cell type. In contrast to T cell acute lymphoblastic leukaemia (ALL), where Notch activation promotes leukemogenesis, induction of Notch signalling in B cell ALL (B-ALL) leads to growth arrest and apoptosis. The Notch target HES1 is sufficient to reproduce this tumour suppressor phenotype in B-ALL by interacting and activating PARP-1 and regulating proapoptotic signals.

Supplier: ProSci Inc.

ZIP2 Antibody: The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

Supplier: RENTEX

Lab coats, Industrial coat, Lab coats, TrenkaTex®, 44 (men), Polyester/cotton, Grey, For men, 65% polyester and 35% cotton, with Sanfor®, Weight: 245 g/m², General Purpose, Pockets: With pockets, Closure type: Press studs / snaps

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

Supplier: FRISTADS KANSAS

Functional, two-tone winter jacket made from Beaver nylon (50% nylon, 50% cotton), a hard-wearing and tear-proof material that is resistant to dirt, oil and water. With faux fur on the collar and on the body, quilted lining in the sleeves and contrasting seams.

Supplier: Avantor

Avantor® ACE® UltraCore SuperC18 solid core (core shell) particle columns are ideal for demanding MS work offering improved MS signal intensity and maximum MS response. These stainless steel columns combine high efficiency separations with low column back pressure. The Encapsulated Bonding Technology (EBT™) greatly increases the ligand coverage of the silica surface and effectively eliminates the effect of unbonded silanol groups on separations. This higher ligand coverage results in improved inertness, chromatographic performance and stability.

Supplier: Hospidex

Sharpsafe®, historic pioneer in protecting against the risk of sharps injuries and sustainability in medical waste packaging management, presents the recycled 5th generation needle containers.