114238 Results for: "Electrodes&pageNo=10"

Supplier: STEMCELL Technologies

Interleukin 15 (IL-15) is a four-alpha helix bundle cytokine with many similar properties to IL-2. The IL-15 receptor is a heterotrimeric receptor composed of IL-15Ra (the high-affinity receptor for IL-15), as well as IL-2/15Rb (CD122) and common gamma chain (CD132). IL-15 binds to IL-15Rα receptor and can then be presented in trans to IL-2/15Rb and common gamma chain on other cells. Trans-presentation is thought to be the major mechanism by which IL-15-mediated responses occur in mice, although may not be necessary in humans (Castillo et al.). The cytoplasmic domains of IL-2/15Rb and common gamma chain mediate signaling to activate JAK/STAT and PI3K pathways. IL-15 supports the survival and proliferation of naïve CD4+ and CD8+ T cells, and promotes homeostasis of memory T cells. IL-15 also promotes the survival and differentiation of NK cells and regulates their cytolytic activity (Ma et al.). This product is animal component-free.

Supplier: STEMCELL Technologies

Interleukin 1 beta (IL-1β) is synthesised as an inactive precursor protein or pro-IL-1β. This precursor is cleaved intracellularly by caspase 1 (IL-1β convertase) to form the active form of the protein that is later secreted (Allan et al.). IL-1β binds to IL-1 receptor and activates intracellular signaling via the MAPK or NF-kB pathway. IL-1β is released by monocytes, tissue macrophages, and dendritic cells in response to infection or injury and induces expression of acute-phase proteins. It also promotes the infiltration of inflammatory and immunocompetent cells from the circulation into the extravascular space and affected tissues, by stimulating the expression of adhesion molecules on endothelial cells. IL-1β also affects other immune cells; for example, it co-stimulates T cell functions together with antigen or mitogen. It also stimulates Th17 differentiation and B cell proliferation in an IL-6-dependent manner. Mice deficient in IL-1β do not show phenotypical differences from wild-type mice; however, they have a reduced response to inflammation, suggesting that IL-1β plays a key role in inflammatory diseases (Dinarello).

Supplier: SARSTEDT

Demeter-Pipette 1,1ml 1 * 1.000 items

Supplier: Abnova

Recombinant protein, adrb2 (np_000015.1) recombinant protein without tag. 1 * 2 µG

Supplier: HIRSCHMANN

Suction tube . 400 mm for em-dispenser up to 10ml 1 * 1 items

Supplier: SAMCO

PASTEUR PIPETTE 7,7 mL, POLYETHYLENE 1 * 500 items

Supplier: IKA

C-MAG Adapter Heating block Adapter for C-MAG 1 * 1 items

Supplier: CHIRAL TECHNOLOGIES

COLUMN CHIRALPAK WH 250X4.6MM 10µM 1 * 1 items

Supplier: Merck

KREBS-HENSELEIT BUFFER MODIFIED, WITH 2000 MG/L GLUCOSE, WITHOUT CALCIUM CHLORIDE AND SODIUM BICARBONATE. CELL CULTURE 1 * 1 Each

Supplier: GERING

HYDROMETER BAUME 40-50 0,1 20C 1 * 1 items

Supplier: Merck

Murashige and skoog basal medium plant cell culture 1 * 44 g

Supplier: MEMMERT

Controller module EXCELLENT with blind for model 500-800 1 * 1 items

Supplier: CHIRAL TECHNOLOGIES

COLUMN CHIRALPAK WH 50X4.6MM 10µM 1 * 1 items

Supplier: Hospidex

Microsyringe 10µl with plunger and interchangeable needle 1 * 1 items

Supplier: CERTOCLAV

Chamber with handles, base MC 12 L 1 * 1 items

Supplier: Amarell

Viscometer-Therm., similar Vogel-Ossag, similar DIN 12785, +90+150:0,2°C, enclosed scale, capillary tube specially coated inside, w ith non-wetting blue special liquid, 470mm long, lower part solid stem 200x5mm, 208mm immersion, Richter-top finish, null

Supplier: SARSTEDT

HOLDER TUBE WITH CLIP 10CM 1 * 15 items

Supplier: STEMCELL Technologies

The platelet-derived growth factor (PDGF) family has five heparin-binding members that assemble into four homodimers (PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD) and one heterodimer (PDGF-AB; Fretto et al.; Li and Eriksson). PDGF signals through the receptor tyrosine kinases PDGFRα and PDGFRβ. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin, such as fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). PDGF-DD promotes growth and survival of renal artery smooth muscle cells and lens epithelial cells, and can act as a macrophage chemoattractant (Changsirikulchai et al.; Lokker et al.; Ray et al.; Uutela et al.).

Supplier: STEMCELL Technologies

Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda et al.). GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 cells (Francisco-Cruz et al.). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton et al.). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz et al.).

Supplier: MACHEREY-NAGEL

COLUMN 100 10µM NH2 250X4MM NUCLEOSIL 1 * 1 KIT

Supplier: VARIAN

TUBING SS REG 10MX1/16INCHX0.25 EA=10MR 1 * 1 items

Supplier: Abnova

Recombinant protein, lefty2( np_003231.2, 1 a.a. - 366 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, fgf2( np_001997, 189 a.a. - 288 a.a.) partial recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, slc14a1( aah50539.1, 1 a.a. - 389 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, traf7( aah24267.1, 1 a.a. - 594 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, kir2dl3( np_056952.2, 1 a.a. - 341 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Thermo Fisher Scientific

TANK CYLIND.COVER LIGHTWEIGHT LLDPE 38 L 1 * 1 items

Supplier: Lovibond Tintometer

Lamp 12V 10W, spare for Lovibond Model F (Tintometer 12 41 02) 1 * 2 items

Supplier: Merck

KREBS-RINGER BICARBONATE BUFFER, WITH 1800 MG/L GLUCOSE, WITHOUT CALCIUM CHLORIDE AND SODIUM BICARBONATE. CELL CULTURE 1 * 1 Each

Supplier: TRESTON

Hook R1, L50 /15kg (5pcs),L50 /15kg (5pcs) 1 * 1 items