Supplier: Abcam

Angiotensin II ELISA kit is a competitive ELISA assay for the quantitative measurement of Ang II in Human serum, plasma, tissue homogenates and other biological fluids.

Supplier: Liebherr

Freezers with a spark-free interior specifically for storing explosive and highly flammable substances in laboratories and in the chemical industry.

Supplier: VWR Collection

The UH5700 UV-Vis-NIR Spectrophotometer is a high-precision benchtop spectrophotometer instrument designed for handling the ultraviolet, visible and near-infrared regions (190 to 3300 nm).

Supplier: Greiner Bio-One

VACUETTE® serum tubes are coated with micronised silica particles which activate clotting when tubes are gently inverted. These tubes are used for routine clinical chemistry, immunohematology, serology and immunology testing.

Supplier: ProSci Inc.

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates several transcript variants diverging in the 3' region including alternate poly A sites. In total, 2 different isoforms are encoded by these variants.

Supplier: ProSci Inc.

ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Supplier: ProSci Inc.

IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x (L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.

Supplier: Portwest

The thoughtfully designed, innovative hi-vis trousers are made from a 50+ UPF rated polyester/cotton fabric which blocks 98% of UV rays. Oxford fabric reinforcement at key abrasion points and triple stitching throughout guarantees maximum durability.

Supplier: Testo

The compact 16 mm vane anemometer testo 416 with telescopic probe and App connection, we can carry out flow measurements in the ventilation ducts of air conditioning and ventilation systems easily, quickly and precisely. The integrated telescope can be extended up to 850 mm, making it easier to work overhead or in large diameter ducts. To ensure that have all the relevant information at our fingertips, the testo 416 automatically calculates time and point average values as well as the volume flow rate. The compact design and the robust housing, the vane anemometer can also stand it if conditions get a little rougher at times.

Supplier: Sartorius Balances

These ultra-micro balances from the Cubis® II range are for highly accurate weighing of microgram quantities, there are also models specifically designed for filter weighing applications.

Supplier: MP Biomedicals

SPINeasy DNA Kit for Water is a high-performance water genomic DNA (gDNA) extraction kit based on silica-membrane spin-column technology. This kit enables quick isolation of gDNA from water in less than 30 min. Water samples are processed using our uniquely formulated Lysis Buffer W1 and Lysing Matrix E to effectively lyse various types of cells. Column W1 provided in the kit has high binding capacity and selectivity for gDNA. The combination of components in the kit extracts gDNA of high yield and purity that is ready for downstream analyses such as PCR, restriction digestion and sequencing.

Supplier: SenseAnywhere

This smart probe featuring a digital SenseAnywhere Bus interface has been especially designed for measuring extreme temperatures in liquid substances. Thanks to its hermetic seal made of PFA, better known as Teflon®, the Hermetically Sealed Pt100 Probe has a high level of chemical resistance. The probe is thanks to its PFA insulation waterproof and easy to clean. It can withstand aggressive substances, allowing it to take measurements in virtually all liquid fluids while being constantly submerged. The PT100 element has a Class A accuracy; measurements are provided at a very high accuracy level.

Supplier: Portwest

Contemporary work trouser made from highly durable ripstop fabric that stretches as you move. Subtle articulation on the knees allow for increased freedom of movement and a high rise back waistband ensures protection in all working positions. Packed with functionality including pre-bent knees, a crotch gusset, two tier knee pad pockets and an adjustable leg length for added convenience.

Supplier: Portwest

The DX4 work trouser is ergonomically designed and uses the targeted placement of dynamic 4X stretch fabrics to give maximum range of movement when working. Triple stitching throughout for maximum durability.

Supplier: EPPENDORF

Eppendorf's twin.tec® 96-well, 150 µl PCR Plates feature a polycarbonate frame and thin-walled polypropylene wells ensuring optimal heat transfer and high rigidity. The SafeCode variants enhance sample identification, while the BioBased options, manufactured using renewable resources, provide an eco-friendly alternative without compromising performance.

Supplier: Merck

Milli-Q® EQ 7008/7016 ultrapure and reverse osmosis (RO, Type 3) water systems are designed to produce consistent ultrapure water quality [resistivity 18,2 MΩ.cm at 25 °C; total organic carbon (TOC) ≤5 ppb] direct from a tap water source. Final ultrapure water quality can be adapted to each user’s specific application requirements. Plus, a range of intelligent design features make it effortless to dispense water as needed and where needed in the lab.

Supplier: VWR Collection

This user friendly portable instrument with robust IP 67 rated housing provides high resolution and accuracy for precise measurements of pH, mV, conductivity and oxygen in field applications (can only be used to measure any two of these at the same time). Complete with waterproof USB output for connection to a computer. GLP compliant.

Supplier: KNICK

This explosion-proof, multi-parameter meter has been specially designed for employment in potentially explosive areas. It is suitable for daily routine pH, ORP, conductivity and oxygen measurements. Waterproof according to IP 66/IP 67.

Supplier: Corning

PS, sterile. The Corning® CellSTACK® culture chambers are available in five sizes and with three different surface treatments.

Supplier: VWR Collection

User friendly instrument, with articulated electrode stand and IP 43-rated housing, provides high resolution and accuracy for precise multi-parameter measurements. This meter can either measure pH/mV and conductivity or pH/mV and oxygen simultaneously. Complete with USB output for connection to a computer. GLP compliant.

Supplier: VWR Collection

These tips are made of high quality, 100% pure, virgin medical grade PP. Made in the highest quality moulds, these tips can be used whenever the work demands a higher standard.

Supplier: AGILENT

The RecoverEase DNA isolation kit recovers high-molecular-weight (100 to 500 kb) genomic DNA that is fully hydrated and ready for multiple applications the next day. DNA can be isolated from whole tissues such as liver, spleen, kidney, brain and testes without hazardous and tedious organic extractions or ethanol precipitations. The RecoverEase DNA isolation kit quickly isolates high-molecular-weight genomic DNA from a variety of tissues without organic solvent extractions or ethanol precipitation.

Supplier: Thermo Scientific

Process a range of general-purpose applications including cell culture, microplate, bioproduction, blood separation, and microbiology with the Thermo Scientific™ Multifuge™ X4 Pro centrifuge series featuring new touch screen technology, making daily tasks easier.

Supplier: Sartorius Balances

The Cubis® II range has a modular design that to allows the customer to choose the components that suit the application area that is of interest. For the customer, this configurable concept delivers quality weighing, together with a high degree of flexibility, without having to invest in expensive equipment that has features that may never be required.

Supplier: Brand

PP.

Supplier: MACHEREY-NAGEL

Nucleic Acid Purification Kits and Reagents, NucleoVac 96 vacuum manifold

Supplier: KNICK

This portable Memosens-based instrument for the analysis of liquids can measure pH/ORP, conductivity (conductive/inductive), oxygen (amperometric/optical) and temperature and features direct printer control. A printer for immediate printing of the calibration record (GLP compliant) can be directly connected to the micro USB port. Waterproof according to IP 66/IP 67.

Supplier: STEMCELL Technologies

Thymus-expressed chemokine (TECK), or CCL25, is a member of the CC family of chemokines that regulates the movement of lymphocytes in the thymus and in the small intestine. TECK induces chemoattraction by binding the chemokine receptor CCR9, which is expressed on immature pre-T cells and thymocytes (Youn et al.; Uehara et al.). In the thymus, TECK is produced by stromal cells, whereas in the small intestine TECK is primarily produced by epithelial cells (Vicari et al.; Bowman et al.; Kunkel et al.). CCR9 is a G protein-coupled receptor and is expressed on most thymocytes, but not on natural killer cells, monocytes, eosinophils, basophils, and neutrophils (Wu et al). In Jurkat cells, binding of TECK to CCL9 has been shown to increase levels of intracellular calcium (Cheng-Rong et al). TECK/CCR9 signaling has also been linked to many cancers, as these molecules have been shown to mediate anti-apoptotic processes by activating the PI3K/AKT signaling pathway, weakening the effect of cytotoxic T cells by regulating STAT signaling. Additionally, TECK induces metastasis by increasing the expression of MMP2 and MMP9 (Tu et al.).

Supplier: OMEGA BIO-TEK

The Mag-Bind® cfDNA Kit CE IVD is designed for rapid and reliable isolation of circulating cell-free DNA from 1 to 4 ml plasma/serum samples.

Supplier: OMEGA BIO-TEK

The E.Z.N.A.® Plasmid Maxi Kit is the maxi scale system to deliver high-quality plasmid DNA using the spin column format, without costly accessories. The HiBind® DNA Maxi column facilitates the binding, washing, and elution steps, thus enabling multiple samples to be simultaneously processed. Although yields vary according to plasmid copy number, E.coli strain, and conditions of growth, 50 to 200 ml of overnight culture in LB medium typically produces 0,5 to 1 mg of high copy number plasmid DNA. Up to 500 ml of culture may be processed when working with low copy number plasmid. The product is suitable for automated fluorescent DNA sequencing (typical reads exceed 800 bp), restriction enzyme digestion, transfection of mammalian cells, transcription invitro, and other applications.