11015 Results for: "Dansyl+hydrazide&pageNo=19&view=list"

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: ALSICO

Men's trousers with a modern, preshaped fitting that offers a professional look without compromising comfort. The fabric is powered by Alsiflex technology, which provides a unique combination of stretch, sustainability, and performance.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: ALSICO

Functional men's trousers for the logistic sector that offer a professional look without compromising comfort. The fabric is powered by Alsiflex technology, which provides a unique combination of stretch, sustainability, and performance.

Supplier: BD Medical

Blood collection sets consist of a needle and a multi-sample Luer adapter, connected by several length of tubing. A Safety-Lok protective shield reduces needlestick risk.

Supplier: ALSICO

These trousers for men are a modern take on the traditional chino, offering a professional look without compromising comfort. The fabric is powered by Alsiflex technology, which provides a unique combination of stretch, sustainability, and performance.

Supplier: ALSICO

These trousers for women are a modern take on the traditional chino, offering a professional look without compromising comfort. The fabric is powered by Alsiflex technology, which provides a unique combination of stretch, sustainability and performance.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

CCDC19 is a 466 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1 and, considering the great number of genes, there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson’s, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Supplier: UVP ULTRA VIOLET PRODUCTS

Cabinet c-10e cabinet only - add 4w el lamp 1 * 1 items

Supplier: ProSci Inc.

Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. SLC19A1 plays a role in maintaining intracellular concentrations of folate.Transport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.

Supplier: FRISTADS KANSAS

Heavy men's piqué poloshirt made of 100% pre-shrunk, ring-spun and combed cotton. The model in grey melange is made of 90% cotton and 10% viscose.

Supplier: FRISTADS KANSAS

T-shirt with short sleeves, made of 44,5% polyester Cocona® and 55,5% standard polyester. The material transports moisture, absorbs odour, dries very quickly and offers UV protection.

Supplier: RENTEX

Trousers, Trousers, Trousers, TrenkaTex®, Canvas 310, 48 (men), Polyester/cotton, Blue, For men, 65 % Polyester, 35 % Cotton, Weight: 310 g/m², General Purpose, Industrial, Pockets: With pockets, Closure type: Buttons

Supplier: Portwest

This flame-retardant boilersuit is most suitable for use within the welding industry, with excellent protection for workers who are exposed to extreme heats. Made of Bizweld 330 fabric (100% cotton drill).

Supplier: FRISTADS KANSAS

Cold resistant jacket made from Airtech® fabric (100% polyamid), a water and windproof, breathable material. The jacket features quilted lining. Exposed areas are reinforced with nylon.

Supplier: BD Medical

These EDTA tubes are used to obtain a whole blood or EDTA plasma sample.

Supplier: ALSICO

Functional women's trousers for the logistic sector that offer a professional look without compromising comfort. The fabric is powered by Alsiflex technology, which provides a unique combination of stretch, sustainability, and performance.

Supplier: Roth Carl

SEKUROKA-UV-VOLLSICHTBRILLE ULTRAS. 1ST 1 * 1 ST

Supplier: Roth Carl

SEKUROKA-UV-VOLLSICHTBRILLE ULTRAS. 1ST 1 * 1 ST

Supplier: AAT Bioquest

Covidyte™ IF670 is a peptide substrate containing 12 amino acid sequence (VNSTLQSGLRKM) that can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide Quencher™ 5 (TQ5) as a quencher and iFluor® 670 as a fluorescent donor on the N-and C-terminals respectively where the fluorescence of iFluor® 670 is effectively quenched by TQ5 when the peptide is intact. When the peptide is hydrolyzed by coronavirus proteases, the iFluor® 670 fragment generates significantly enhanced fluorescence since its fluorescence is no longer quenched by TQ5. The activity of coronavirus proteases can be effectively monitored by the fluorescence intensity of iFluor® 670. Covidyte™ IF670 is a robust high throughput screening tool for searching inhibitors of coronavirus proteases. Comparing to the commonly used EDANS substrates (such as Covidyte™ ED450), the iFluor® 670 substrate has much stronger and longer fluorescence that is less interfered by coloured compounds that often cause false positive hits.

Supplier: FRISTADS KANSAS

Industrial jacket made of 65% polyester and 35% cotton, with soft nap on reverse side. The royal blue jacket is available with different accent and piping colours.

Supplier: RENTEX

Vests made from stretch fabric, 60% polyester, 35% cotton and 5% DOW XLA.

Supplier: SIOEN

Protective, bicoloured jacket made of 100% soft double-sided polyester fleece providing good cold protection. With anti-pilling treatment and stitched seams. Can be zipped into the rain jacket 608Z.

Supplier: FRISTADS KANSAS

Shirt made of 100% spunbounded cotton (single jersey), with anti-pilling treatment. The grey melange version is manufactured from 85% cotton and 15% viscose.

Supplier: RENTEX

Lab coats, Lab coats, Lab coats, TrenkaTex®, 52 (men), Cotton, Grey, For men, Baumwolle, Weight: 320 g/m², Industrial, General Purpose, Pockets: With pockets, Closure type: Press studs / snaps

Supplier: DGP INTELSIUS

ORCA Response is a multi-use, handheld, temperature-controlled packaging solution for transporting smaller payloads of red blood cells, platelets, pharmaceutical products and be easily carried and stored, making it the ideal solution for taking personal medicines on long journeys, including suitability as hand luggage on aeroplanes.

Supplier: Corning

Manufactured from optically clear virgin polystyrene.

Supplier: FRISTADS KANSAS

Industrial jacket made of 65% polyester and 35% cotton, with soft nap on reverse side. The navy blue jacket is available with different accent and piping colours.

Supplier: RENTEX

Bib and braces, Overall, bib and brace, Bib and braces, TrenkaTex®, 48 (men), Polyester/cotton, Hi-vis orange, For men, Polyester Baumwolle, Weight: 270 g/m², HiVis, General Purpose, Industrial, Pockets: With pockets