7717 Results for: "Covers&pageNo=42&view=easy"

Supplier: Bioss

Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalisation of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalysed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses.

Supplier: Biotium

CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and others. It is involved in T-cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.

Supplier: Biotium

CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and others. It is involved in T-cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.

Supplier: Abcam

Rabbit monoclonal [EPR23251-42] to PAEP/Glycodelin - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR28366-42] to GABA A Receptor beta 2/GABRB2.

Supplier: VWR Chemicals

Organic Standard, Aroclor 1242 (PCB-mixture, 42% chlorinated) 1,000 µg/ml in hexane, Pack type: Glass ampoule

Supplier: Abcam

Alexa Fluor® 488 Rabbit monoclonal [EPR19025-42] to Mesothelin.

Supplier: Abcam

FITC Mouse monoclonal [F15-42-1] to CD90/Thy1.

Supplier: Abcam

Rabbit monoclonal [EPR18549-42] to STAT2 (phospho Y690) - ChIP Grade.

Supplier: Abcam

Rabbit monoclonal [EPR23367-42] to Bone Sialoprotein - BSA and Azide free (Capture).

Supplier: Abcam

Rabbit monoclonal [EPR26639-42] to Desmoglein 2/DSG2 - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPPTX-R6-42-12] to Vitamin D3.

Supplier: Abcam

Alexa Fluor® 647 Rabbit monoclonal [EPR19025-42] to Mesothelin.

Supplier: Abcam

Alexa Fluor® 488 Rabbit monoclonal [EPR27110-42] to CD98.

Supplier: Abcam

Rabbit monoclonal [EPR19426-42] to Oncostatin M/OSM - BSA and Azide free (Capture).

Supplier: Abcam

Rabbit monoclonal [mOC64] to beta Amyloid 1-42 - Low endotoxin, Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR26927-42] to IL-36R - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR24109-42] to TCF-4/TCF7L2 - BSA and Azide free (Capture).

Supplier: Bioss

Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalisation of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalysed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses.

Supplier: Abcam

Alexa Fluor® 594 Rabbit monoclonal [EPR27110-42] to CD98.

Supplier: Abcam

Alexa Fluor® 647 Rabbit monoclonal [EPR27110-42] to CD98.

Supplier: Abcam

APC Rabbit monoclonal [EPR23000-42] to CD134 / OX40L receptor.

Supplier: Abcam

Rabbit monoclonal [EPR23000-42] to CD134 / OX40L receptor - BSA and Azide free.

Supplier: Beckman Coulter

Windshielded, six-place rotor with aluminium rotor yoke and removable aluminium swinging buckets. Buckets are interchangeable with microplate carriers (358682) for spinning microtitre plates and minitube racks. Holds up to six litres, six blood bags, or six microtitre plate carriers. Accepts all multi-disc adapters. A kit is available to convert this rotor to a JS-4.2SM (356501)

Supplier: Abcam

PE Rabbit monoclonal [EPR23000-42] to CD134/OX40L receptor.

Supplier: Bioss

Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.

Supplier: Abcam

Rabbit monoclonal [EPR24854-42] to SARS-COV-2 nsp8 - BSA and Azide free.

Supplier: Bioss

Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.

Supplier: DYNACO EUROPE

Lower guide rail M2 left (42) Muthylen

Supplier: Bioss

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008].