115178 Results for: "Carbonyl(dihydrido)tris(triphenylphosphine)ruthenium(II)&pageNo=10&view=list"

Supplier: Shenandoah Biotechnology

Interleukin 32 alpha (IL-32 α) is one of six known splice variants of the IL-32 gene. IL-32 α induces the macrophage production of inflammatory cytokines, such as interleukin 8 (IL-8), tumor necrosis factor-alpha (TNF-α), and macrophage inflammatory protein 2 (MIP-2). IL-32 α expression is increased after the activation of T cells, natural killer (NK) cells, and interferon gamma-treated epithelial cells.

Supplier: Thermo Fisher Scientific

NeutrAvidin™ agarose is a beaded agarose resin of immobilised NeutrAvidin™ protein, a modified form of avidin with exceptional biotin-binding characteristics for affinity purification methods.

Supplier: Cytiva

A chromatography resin for purification of recombinant proteins tagged with Strep-tag II and Twin-Strep-tag. These proteins bind very specifically to the immobilised Strep-Tactin XT ligand giving highly pure target protein.

Supplier: Shenandoah Biotechnology

Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-κB and MAPK signaling pathways. IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells.

Supplier: ProSci Inc.

The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signalling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

Supplier: MP Biomedicals

5-Phosphorylribose-1-pyrophosphate Sodium Salt Hydrate has been used in a study to assess the relationship between the muscarinic receptor cationic current and internal calcium in guinea-pig jejunal smooth muscle cells. It has also been used in a study to investigate inhibitors of the bacterial cell wall biosynthesis of the enzyme Mur D.

Supplier: Merck

cis-4-Hydroxy-D(+)-proline, Sigma-Aldrich®

Supplier: Thermo Fisher Scientific

Iron(III) nitrate nonahydrate 98+% ACS

Supplier: Thermo Fisher Scientific

The UpCell™ surface is a temperature-responsive cell culture surface that enables harvesting of cells with high viability and intact surface proteins for culture passaging, single-cell analyses and cell transplantation research. The UpCell™ surface enables harvesting of cell sheets and creation of 3D tissue models held together by normal cell junctions and extracellular matrix deposited by the cells.

Supplier: Merck

EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride), Sigma-Aldrich®

Supplier: Brady

FreezerBondz thermal transfer printers labels can be applied to frozen surfaces including glass and polypropylene stored in liquid nitrogen. These labels are on a 1" core, a 'smaller core' than the majority of labels. Recommended printer for these is the BBP11-34L printer.

Supplier: USP

USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

Supplier: Bioss

MP21 is a member of the EMP24/GP25L/p24 cargo family of proteins that regulates vesicular trafficking in the early secretory pathway. TMP21 is a ubiquitously expressed single-pass type I membrane protein localizing to the Golgi cisternae and the plasma membrane. It contains one GOLD (Golgi dynamics) domain and participates in protein transport and quality control between the endoplasmic reticulum (ER) and the Golgi complex. In addition, TMP21 is a component of the heteromeric secretase complex (or Presenilin complex) and functions to regulate the ?secretase activity. Two isoforms, namely TMP21-I and TMP21-II, exist for this protein.

Supplier: Bioss

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Supplier: Bioss

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.

Supplier: Bioss

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.

Supplier: THARMAC GmbH

Versatile cytocentrifuges suitable for small and large sample volumes, designed for thin layer and mono layer cell preparations in medical applications such as cytology, urology, microbiology, haematology, immunocytochemistry, virology and oncology.

Supplier: Brady

PermaSleeve® PS heat-shrink polyolefin (B-342) wire marking sleeves combine speed, ease of use, and permanence to create long-lasting, high quality identification.

Supplier: USP

USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

Supplier: S.C.A.T.

The SCAT SafetyWasteCaps provide maximum safety for your HPLC liquid disposal. Safely dispose of your liquid laboratory waste without contaminating the ambient air by using SafetyWasteCaps with integrated exhaust air filters. These high-performance filters regulate the air pressure balance and prevent the escape of vapors due to the resulting overpressure in the disposal container. The variety of closures, connections and thread sizes allows optimal adaptation to your HPLC situation. Additional versions with grounding connections, level controls or safety funnels or offer every convenience for safe disposal.

Supplier: ENZO LIFE SCIENCES

Novel inhibitor of NAD(P)H oxidase (Nox). In vascular smooth muscle cells VAS-2870 completely abolished PDGF-mediated NAD(P)H oxidase activation and ROS production (100% at 10µM). It inhibits PDGF-induced chemotaxis but not proliferation of VSMC. In mouse embryonic stem cells VAS-2870 blocked PDGF-BB-induced vasculogenesis. OxLDL-induced ROS formation in human endothelial cells was completely inhibited by VAS-2870 (100% at 5µM). VAS-2870 inhibits PMS-induced oxidative burst in HL-60 cells (IC50=2µM).

Supplier: USP

USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

Supplier: bimos

Neon supports the forward-leaning sitting position that is often necessary in lab work. Its modern design matches the high-tech laboratory environment perfectly and of course it has all the characteristics you would expect of a good laboratory chair. It is seamless, easy to clean, washable, and resistant to disinfectants. So, Neon is the ideal solution for the laboratory, when a really comfortable ergonomic chair is needed.

Supplier: Bioss

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Supplier: Bioss

ADAMTS10 is a member of the ADAMs family of proteinases with Thrombospondin motifs. The catalytic site of ADAMTS10 is typical of the metalloproteinase catalytic domains, with an HExxHxxxxxH sequence, perhaps giving these enzymes some shared specificity. ADAMTS10 is closest in homology to ADAMTS6, sharing 53% overall identity. Functional mutations in ADAMTS10 have been linked to Weill Marchesani syndrome, a connective tissue disorder marked by fibrillin 1 misprocessing. ADAMTS10 has also been reported to be over expressed in breast cancer tissues and cell lines.

Supplier: Bioss

The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Supplier: Bohlender

Safe collection of hazardous waste is an important part of the laboratory work routine. b.safe waste caps connect waste lines from your HPLC/UHPLC leak-tight with your waste container. The waste caps are available in various sizes to fit your specific waste container safely.

Supplier: USP

USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

Supplier: Apollo Scientific

(2R,3R)-(-)-2,3-Butanediol 99%

Supplier: TECHNICAL QUARTZ SOLUTIONS

Crucible lid, For Ø: 76 mm, Quartz