112980 Results for: "Bromobenzene-[D5]&pageNo=10&view=easy"

Supplier: Roth Carl

Fatty acid methyl ester mixture 1 * 100 mg

Supplier: Roth Carl

Sekuroka-5-finger gloves 1 * 1 PAIR

Supplier: EPPENDORF

Eppendorf® Safe-Lock tubes 0,5 ml - Microtube ensures secure sample storage. With a unique locking mechanism, these tubes prevent accidental opening, safeguarding precious samples. Ideal for PCR, these tubes offer reliability and ease in a compact design.

Supplier: EPPENDORF

Eppendorf Deepwell plates 96-well, 2000 µl offer efficient sample handling with features like OptiTrack® matrix for rapid identification and g-Safe® technology for stability during centrifugation. SafeCode variants provide secure three-level coding, including error correction for reliable identification, ensuring flexibility and accuracy in experimental workflows.

Supplier: Portwest

Breathable jacket made of 300D Oxford weave which features contemporary design 4-in-1 versatile jacket that offers four combinations: light weight outer, outer with body warmer combined, wear-alone body warmer and reverse colour body warmer.

Supplier: STEMCELL Technologies

Transforming growth factor (TGF) beta 3 is a member of the TGF-β superfamily and regulates diverse cellular phenotypes. TGF-beta 3 binds to serine-threonine kinase type I and II receptors and activates signal transduction through SMAD2/3 proteins, thus regulating a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (Massagué; McDowell et al.). TGF-beta 3 enhances glycosaminoglycan production by mesenchymal stromal cells, stimulates scar-free healing, and improves glucose tolerance and phenotypic changes in adipocyte morphology (Hall et al.; Holton et al.). TGF-beta 3 induces proliferation of posterofrontal suture-derived mesenchymal stromal cells, and stimulates expression of fibroblast growth factors 2 and 18 (James et al.).

Supplier: TIGER-VAC

Textile filtering bag for CR-1 #212502 with black plastic ring. 1 * 1 Each

Supplier: PURITAN MEDICAL

SWAB STERILE COTTON TIP PLASTIC HANDLE 1 * 2.000 items

Supplier: Retsch GmbH

Test Sieve ISO 3310/1 450x100mm 125.00mm stainless steel with compliance certificate acc. EN 10204 2.1 1 * 1 items

Supplier: FELDTMANN HELMUT

WEISS Norm: EN 388 Träger: 60% Baumwolle/40% Polyester, weiß Beschichtung: Vinyl-Noppen, schwarz - Profi-Qualität - Grobstrick, nahtlos/ 7G - schwarze Grip-Noppen auf der Innenhandfläche und dem Handrücken - sehr gute Passform und sicherer Griff - at 1 * 240 PAAR

Supplier: witeg Labortechnik

Flask, 10ml, ST14/23, pear shaped, outer diameter 33mm, height 70mm, borosilicate glass 3.3 1 * 1 items

Supplier: witeg Labortechnik

Flask for collecting nitrogen 10ml, with cylindrical needle valve,120x16mm, st14/23,acc. to schlenk, null

Supplier: witeg Labortechnik

Flask for collecting 10ml,with cylindrical stopcock, 120x16mmmm, st14/23, acc. to schlenk, null

Supplier: Sartorius Balances

The Cubis® II range has a modular design that to allows the customer to choose the components that suit the application area that is of interest. For the customer, this configurable concept delivers quality weighing, together with a high degree of flexibility, without having to invest in expensive equipment that has features that may never be required.

Supplier: IKA

Powerful laboratory stirrers for quantities up to 40 or 100 litres (H₂O). Units automatically adjust the speed through microprocessor-controlled technology within the speed range of 0/30 to 2000 min⁻¹ (EUROSTAR 60 models) or 0/30 to 1300 min⁻¹ (EUROSTAR 100 models). Safety circuits ensure automatic cut-off in anti-stall or overload conditions. The actual shaft and pre-set speed are constantly monitored, and variations adjusted automatically. This guarantees a constant speed even with changes in sample viscosities.

Supplier: STEMCELL Technologies

Indian hedgehog (IHH) is one of three proteins in the hedgehog family which includes sonic hedgehog and desert hedgehog. Hedgehog proteins are important signaling molecules, acting through patched and smoothened receptors. During embryonic development, they are expressed in the fetal lung, gut, stomach, liver, kidney, and pancreas. IHH is strongly expressed in cartilage and regions of developing bone, and its signaling regulates growth and differentiation of bone tissue (Marigo et al.; Valentini et al.; St-Jacques et al.). IHH is also involved in yolk sac vasculogenesis, indicating a role in the differentiation of epiblast cells into endothelial and red blood cells (Byrd et al.). IHH induces the expression of parathyroid hormone-related peptide (PTHrP), which negatively regulates IHH during chondrocyte differentiation and proliferation (Vortkamp et al.).

Supplier: Thermo Fisher Scientific

These spin columns provide a fast, easy to use format for purifying GST-fusion proteins from cellular lysates. The glutathione is immobilised through its central sulfhydryl onto 6% crosslinked agarose resin. Purification of GST-fusion proteins using glutathione (GSH) agarose beads is well documented and provides a one-step, high purity affinity purification.

Supplier: HUBER

These circulators with insulated refrigeration baths are designed for direct temperature control from −20 to +200 °C. The units are suitable for a number of typical heating and cooling tasks such as sample temperature control, materials testing, quality control and analyses.

Supplier: STEMCELL Technologies

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang et al.; Dorssers et al.; Broughton et al.). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton et al.). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock et al.).

Supplier: EPPENDORF

Eppendorf Deepwell plates 96-well, 500 µl offer efficient sample handling with features like OptiTrack® matrix for rapid identification and g-Safe® technology for stability during centrifugation. SafeCode variants provide secure three-level coding, including error correction for reliable identification, ensuring flexibility and accuracy in experimental workflows.

Supplier: STEMCELL Technologies

Interleukin 13 (IL-13) is a type I cytokine, and signals through type I cytokine receptors to activate JAK/STAT and IRS-1/IRS-2 pathways. IL-13 is produced by T cells and innate lymphoid cells (Pulendran and Artis) and it inhibits production of pro-inflammatory cytokines, prostaglandins, and reactive oxygen and nitrogen species by monocytes and macrophages (Hershey). Unlike human B cells, IL-13 has no effect on mouse B cell development and function. IL-13 promotes eosinophil survival, activation, and recruitment, and also activates mast cells (Hershey). IL-13 regulates gastrointestinal parasite expulsion, airway hyperresponsiveness, allergic inflammation, tissue eosinophilia, goblet cell hyperplasia, intracellular parasitism, tissue remodeling, tumor cell growth, and fibrosis. IL-13 induces hypercontractility of smooth muscles by directly acting on the muscle cells as well as the enteric nerves (Wynn).

Supplier: STEMCELL Technologies

Interleukin 33 (IL-33) is a pro-inflammatory cytokine from the IL-1 family. It binds to the ST2 receptor and activates NF-kB and MAPK pathways. IL-33 is expressed by epithelial cells, smooth muscle cells, and fibroblasts in various tissues and organs, as well as resting basophils, mast cells, eosinophils, natural helper cells, group 2 innate lymphoid cells, dendritic cells, and activated macrophages (Schmitz et al.; Yasuda et al.). It contributes to allergic inflammation by stimulating production of the cytokines IL-4, IL-5, and IL-13 in Th2 cells, and stimulates host defense against microbial and viral infections (Liew; Yasuda et al.). In the central nervous system, IL-33 is produced by endothelial cells and astrocytes. It induces proliferation of microglia and mediates production of pro-inflammatory cytokines (Yasuoka et al.).

Supplier: ProSci Inc.

Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that regulate transcription by selectively deacetylating or acetylating the eta-amino groups of lysines located near the amino termini of core histone proteins (1). Eight members of HDAC family have been identified in the past several years (2,3). These HDAC family members are divided into two classes, I and II. Class I of the HDAC family comprises four members, HDAC-1, 2, 3, and 8, each of which contains a deacetylase domain exhibiting from 45 to 93% identity in amino acid sequence. Class II of the HDAC family comprises HDAC-4, 5, 6, and 7, the molecular weights of which are all about two-fold larger than those of the class I members, and the deacetylase domains are present within the C-terminal regions, except that HDAC-6 contains two copies of the domain, one within each of the N-terminal and C-terminal regions. Human HDAC-1, 2 and 3 were expressed in various tissues, but the others (HDAC-4, 5, 6, and 7) showed tissue-specific expression patterns (3). These results suggested that each member of the HDAC family exhibits a different, individual substrate specificity and function in vivo. HDAC8 interacts with PEPB2-MYH11, a fusion protein consisting of the 165 N-terminal residues of CBF-beta (PEPB2) with the tail region of MYH11 produced by the inversion Inv(16)(p13q22), a translocation associated with acute myeloid leukemia of M4EO subtype. The PEPB2-MYH1 fusion protein also interacts with RUNX1, a well known transcriptional regulator, suggesting that the interaction with HDAC8 may participate to convert RUNX1 into a constitutive transcriptional repressor.

Supplier: STEMCELL Technologies

Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine that activates NF-kB, MAPK, and PI3K/AKT pathways. Activated T cells and macrophages are the primary producers of TNF-α in response to inflammation and infectious conditions. Many other cell types have been shown to produce TNF-α, among them B cells, NK cells, mast cells, neutrophils, dendritic cells, microglia, endothelial cells, smooth muscle cells, cardiomyocytes, and fibroblasts. TNF-α has cytotoxic effects on cancer cells in vitro by stimulating anti-tumor immuno- suppressive responses. TNF-α stimulates expression of E- and P-selectins, thus facilitating adhesion of neutrophils, monocytes, and memory T cells to activated platelets and endothelial cells (Zelová and Hosek). Other effects of TNF-α include vasodilatation and edema formation.

Supplier: GLASWARENFABRIK KARL HECHT

SLIDE 75X55X1,0MM 1-SIDE MAT EDG 1 * 1.000 items

Supplier: witeg Labortechnik

Flask for collecting nitrogen 10ml, with cylindrical stopcock,120x16mm, st14/23,acc. to schlenk, null

Supplier: Roth Carl

VAKUUMREGLER TYP VAR 1ST 1 * 1 ST

Supplier: GLASWARENFABRIK KARL HECHT

TEST TUBE 75X16 MM SPECIAL DESIGN 1 * 1.000 items

Supplier: EPPENDORF

LOWER PART 0.5-10UL 1 * 1 items

Supplier: Agencinox

FOOTBOARD ONE STEP 300X340X210MM 1 * 1 items