112021 Results for: "Blocking+Buffers&pageNo=10&view=list"

Supplier: STEMCELL Technologies

Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of glycoproteins that regulate hematopoietic cell proliferation, differentiation, and function. It is a key cytokine involved in the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf andamp; Nicola). G-CSF causes a range of effects including a transient reduction of SDF-1 expression (Petit et al.), the activation of metalloproteases that cleave VCAM-1 (Levesque et al.), and the release of norepinephrine from the sympathetic nervous system (Katayama et al.), leading to the release or mobilisation of hematopoietic stem cells from the bone marrow into the periphery. The G-CSF receptor is expressed on a variety of hematopoietic cells, including myeloid-committed progenitor cells, neutrophils, granulocytes, and monocytes. In addition to hematopoietic cells, G-CSF is also expressed in cardiomyocytes, neuronal cells, mesothelial cells, and endothelial cells. Binding of G-CSF to its receptor leads to activation of the JAK/STAT, MAPK, PI3K, and AKT signal transduction pathways.

Supplier: Portwest

This jacket offers exceptional weather protection, comfort, and warmth while utilising the latest innovations in recycled fabrics. The outer shell, lining, and wadding are certified recycled polyester, and the packaging is derived from sugarcane, allowing the wearer to champion sustainability without compromising on performance.

Supplier: TRESTON

Hook R29, L80 (5pcs),L80 (5pcs) 1 * 1 items

Supplier: AMETEK

[EN]CIRCULATOR BATH 28L MX CONTROL STAND 1 * 1 ST

Supplier: HAMILTON BONADUZ

calibrate with certificate 1 * 1 items

Supplier: Abnova

Recombinant protein, fpr1 (np_002020.1) recombinant protein without tag. 1 * 2 µG

Supplier: GERING

SACCHARIMETER 0-5: 0.05 BRIX + TH-TP27 1 * 1 items

Supplier: Quantabio

Ultra-Plex™ 1-Step ToughMix® is a ready-to-use, 4X-concentrated master mix for reverse transcription quantitative PCR (RT-qPCR) of RNA templates using hybridisation probe detection chemistries such as TaqMan® 5’-hydrolysis probes on Real-Time PCR systems that utilise ROX passive reference with 490 nM excitation. First-strand cDNA synthesis and PCR amplification are carried out in the same tube without opening between procedures. It is ideal for highly sensitive quantification of RNA viruses or low abundance RNA targets in uni- or multiplexed RT-qPCR applications as well as high throughput gene-expression studies. The system has been optimised to deliver maximum RT-qPCR efficiency, sensitivity, and specificity in reduced reaction volumes and fast cycle times. Ultra-Plex™ 1-Step ToughMix® contains all required components for RT-qPCR except RNA template and probe. It is compatible with all dual-labeled probe chemistries.

Supplier: TRESTON

Hook R10, L33 (5pcs),L33 (5pcs) 1 * 1 items

Supplier: Abnova

Recombinant protein, gpr55 (np_005674.2) recombinant protein without tag. 1 * 2 µG

Supplier: TOSOH Bioscience

COLUMN TSKGEL GUARD SUPERHZ-H 10µM 1 * 1 items

Supplier: SARSTEDT

Demeter-Pipette 1,1ml 1 * 1.000 items

Supplier: Abnova

Recombinant protein, adrb2 (np_000015.1) recombinant protein without tag. 1 * 2 µG

Supplier: CERTOCLAV

Chamber with handles, base MC 12 L 1 * 1 items

Supplier: Hospidex

Microsyringe 10µl with plunger and interchangeable needle 1 * 1 items

Supplier: CHIRAL TECHNOLOGIES

COLUMN CHIRALPAK WH 50X4.6MM 10µM 1 * 1 items

Supplier: OMNIFIT

Frits, ptfe, 40 micron for 10mm endpieces 1 * 20 items

Supplier: SciLabware

BOTTLE REAGENT WIDE NECK 10L 1 * 1 items

Supplier: Amarell

Viscometer-Therm., similar Vogel-Ossag, similar DIN 12785, +90+150:0,2°C, enclosed scale, capillary tube specially coated inside, w ith non-wetting blue special liquid, 470mm long, lower part solid stem 200x5mm, 208mm immersion, Richter-top finish, null

Supplier: Merck

Murashige and skoog basal medium plant cell culture 1 * 44 g

Supplier: MEMMERT

Controller module EXCELLENT with blind for model 500-800 1 * 1 items

Supplier: GERING

HYDROMETER BAUME 40-50 0,1 20C 1 * 1 items

Supplier: SAMCO

PASTEUR PIPETTE 7,7 mL, POLYETHYLENE 1 * 500 items

Supplier: REAGECON

Turbidity standard Non Ratio 10NTU 1 * 100 mL

Supplier: HIRSCHMANN

Suction tube . 400 mm for em-dispenser up to 10ml 1 * 1 items

Supplier: Merck

KREBS-HENSELEIT BUFFER MODIFIED, WITH 2000 MG/L GLUCOSE, WITHOUT CALCIUM CHLORIDE AND SODIUM BICARBONATE. CELL CULTURE 1 * 1 Each

Supplier: CHIRAL TECHNOLOGIES

COLUMN CHIRALPAK WH 250X4.6MM 10µM 1 * 1 items

Supplier: SARSTEDT

HOLDER TUBE WITH CLIP 10CM 1 * 15 items

Supplier: STEMCELL Technologies

Interleukin 21 (IL-21) is a pleiotropic cytokine that is composed of four α-helical bundles and primarily produced by natural killer T (NKT) cells, T follicular helper (Tfh) cells, and Th17 cells (Spolski and Leonard 2008). IL-21 signals via heterodimers of the IL-21 receptor (IL-21R) and the IL2RG encoded common cytokine receptor γ-chain (Parrish-Novak et al.; Ozaki K et al. 2000), and utilizes the JAK/STAT, MAPK, and PI3K pathways (Spolski and Leonard 2014). IL-21 has been shown to have a critical role in regulating immunoglobulin production and differentiation of the pro-inflammatory Th17 population of cells (Ozaki et al. 2002; Nurieva et al.). Additionally, IL-21 specifically sustains CD8+ T cell effector activity and provides a mechanism of CD4+ T cell help during chronic viral infection (Elsaesser et al.). IL-21 signaling was also found critical for the development of type 1 diabetes in NOD mice (Sutherland et al.) and control of T cell autoimmunity by regulatory B cells (Yoshizaki et al.).

Supplier: STEMCELL Technologies

Interleukin 21 (IL-21) is a pleiotropic cytokine that is composed of four α-helical bundles and primarily produced by natural killer T (NKT) cells, T follicular helper (Tfh) cells, and Th17 cells (Spolski and Leonard 2008). IL-21 signals via heterodimers of the IL-21 receptor (IL-21R) and the IL2RG-encoded common cytokine receptor γ-chain (Parrish-Novak et al.; Ozaki K et al. 2000), and utilizes the JAK/STAT, MAPK, and PI3K pathways (Spolski and Leonard 2014). IL-21 has been shown to have a critical role in regulating immunoglobulin production and differentiation of the pro-inflammatory Th17 population of cells (Ozaki et al. 2002; Nurieva et al.). Additionally, IL-21 specifically sustains CD8+ T cell effector activity and provides a mechanism of CD4+ T cell help during chronic viral infection (Elsaesser et al.). IL-21 signaling was also found critical for the development of type 1 diabetes in NOD mice (Sutherland et al.) and control of T cell autoimmunity by regulatory B cells (Yoshizaki et al.). This product is animal component-free.