106550 Results for: "Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane+(BIS-TRIS)&pageNo=25"

Supplier: Hach

COPPER FREE REAGENT POWDER PILLOWS 1 * 100 items

Supplier: EPPENDORF

Eppendorf's twin.tec® 96-well, 150 µl PCR Plates feature a polycarbonate frame and thin-walled polypropylene wells ensuring optimal heat transfer and high rigidity. The SafeCode variants enhance sample identification, while the BioBased options, manufactured using renewable resources, provide an eco-friendly alternative without compromising performance.

Supplier: Molekula

1,10-Phenanthroline hydrochloride monohydrate

Supplier: TRESTON

Middle plate 90-130/150 L=300 1 * 1 items

Supplier: ZWIEBEL

WEIGHT SET 1 MG-1KG 25UNITS CLASS E1 1 * 1 SET

Supplier: CUSTOM MADE CHEMICALS LAB

33 COMPONENTS MIX 1 * 10 Ampoul

Supplier: LGC Standards PROMOCHEM

N-TETRACONT. 20 MG AND N-DECANE IN HEXAN 1 * 100 mL

Supplier: VARIAN

TUBING SS REG 25MX1/4INCHX4.4 EA=25MR 1 * 1 items

Supplier: CUSTOM MADE CHEMICALS LAB

STANDARD SOLUTION 54 COMPONENTS 1 * 1 Ampoul

Supplier: Merck

VISCOSITY STANDARD UKAS ISO/IEC17025 1 * 500 mL

Supplier: DWK Life Sciences

Tube screw 100x16mm, GPI 15-415, borosilicate. 1 * 1 items

Supplier: Merck

VISCOSITY STANDARD UKAS ISO/IEC17025 1 * 500 mL

Supplier: IKA

Tool kit for dismantling T25 homogeniser dispersing tools,IKA 1 * 1 items

Supplier: MACHEREY-NAGEL

QUANTOFIX CHLORINE 500 TEST STRIPS 1 * 100 Tests

Supplier: TOSOH Bioscience

TSKGel BUTYL-NPR Column, Custom Made Column, 4.6mmID x 10cm 1 * 1 items

Supplier: HIRSCHMANN

VOL.FLASK 25ML NS12/21 A HOLLOW GLAS WI 1 * 2 items

Supplier: MACHEREY-NAGEL

QUANTOFIX® test strips meet all requirements of a modern rapid test. The colour of the reactive pad changes depending on the concentration of an analyte in the sample. The evaluation is usually carried out visually by comparison of the reaction colour with a multi-stage colour scale. These test strips are immediately ready to use. They do not require additional accessories. The test strips are intended for single-use, maintenance or calibration are not required.

Supplier: STEMCELL Technologies

Interleukin 31 (IL-31), a four-helix bundle inflammatory cytokine, belongs to the IL-6 cytokine family which includes IL-6, oncostatin M, leukemia inhibitory factor (LIF), and cardiotrophin-1 ( Dillon et al.). IL-31 signals through a heterodimer composed of IL-31RA (also known as gp130-like receptor or GPL) and the oncostatin-M receptor (OSMR), both of which are expressed on monocytes (Diveu et al.; Ghilardi et al.), epithelial cells (Ip et al.), and keratinocytes (Kato et al.). Signaling through the GPL/OSMR complex activates the JAK/STAT, RAS/ERK, and PI3K/AKT signaling pathways, resulting in the downstream activation of STAT1, STAT3, and STAT5 transcription factors (Cornelissen et al.; Dambacher et al.; Dillon et al.; Ip et al.). IL-31 responses have been associated with allergic responses and inflammatory skin diseases including atopic dermatitis (Cornelissen et al.; Gangemi et al.).

Supplier: EPPENDORF

Eppendorf Tubes® with screw cap are an ideal choice when working with medium-sized sample volumes (0,5 to 5,0 ml). SafeCode variants enhance sample identification, while the BioBased option, manufactured using renewable resources, provides an eco-friendly alternative without compromising performance.

Supplier: STEMCELL Technologies

Use Interferon beta (IFN-β) to modulate the activity of genes that control dendritic cell activation, T cell survival, NK cell activation, chemokine expression, lymph node retention, and antiproliferative and antiviral effects (Dunn et al. Nat Rev Immunol, 2006). IFN-β binds to a receptor complex composed of IFNAR1 and IFNAR2, and initiates signal transduction via the JAK/STAT pathway. It is predominantly produced by fibroblasts, with smaller amounts from plasmocytoid dendritic cells. Macrophages and endothelial cells secrete IFN-β in response to viral infection (Reder and Feng. Front Immunol, 2013). IFN-β suppresses Th17 cells by affecting expression of IL-4, IL-10, and IL-27, and is a first-line treatment for multiple sclerosis. IFN-β was also shown to expand regulatory T cells and limit T cell trafficking to the central nervous system (Inoue and Shinohara. Immunology, 2013). Of the two IFN-β variants (IFN-β1 and IFN-β3), this product is the IFN-β1 form.

Supplier: STEMCELL Technologies

Fractalkine (CX3CL1) is a unique chemokine belonging to the CX3C family, and is characterized by a C-X3-C cysteine motif within the chemokine domain, near the amino terminus of the protein (Bazan et al.). The chemokine domain is connected to an extended mucin-like stalk, followed by a transmembrane region, and a C-terminal intracellular domain (Imai et al.; Jones et al.). The protein signals through interaction with a single receptor, CX3CR1, expressed on monocytes, natural killer cells, T cells, microglia, and smooth muscle cells. Fractalkine is upregulated in endothelial cells by inflammatory signals and is synthesized as a membrane-bound molecule that mediates cell migration and adhesion (White and Greaves). Cleavage at the base of the stalk by metalloproteinases generates a soluble chemokine, which functions as a potent chemoattractant of target cells (Garton et al.; Apostolakis and Spandidos). Fractalkine has been implicated in pathology of inflammatory diseases, such as atherosclerosis and other vascular diseases, and has anti-apoptotic functions (White and Greaves).

Supplier: HIRSCHMANN

Flask, volumetric, capacity 25ml, class A, USP certificate 1 * 1 items

Supplier: Hospidex

Microsyringe 25µl GC standard with glass handle and fixed needle 1 * 1 items

Supplier: HIRSCHMANN

VOL.FLASK 25ML NS10/19 A HOLLOW GLASS 1 * 2 items

Supplier: CONSORT

REDOX STANDARD SOLUTION 500 ML 124 MV 1 * 500 mL

Supplier: MP Biomedicals

Applications
Guanidine hydrochloride can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA. It is a strong chaotropic agent useful for the denaturation and subsequent refolding of protein, it can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA.
Product Description
The crystal structure of Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds,it is a strong chaotropic agent.Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a freeflowing powder with solid material dispersed throughout, or a solid. The quality of the product does not appear to be affected and solutions prepared from the free-flowing and lumpy guanidine HCl appear identical

Grade: Ultra Pure
Purity: >99%
Keywords: Guanidium chloride, chaotropic agent
Key Applications: Chaeotropic agent
Product Type: Biochemicals
Biochemical Category: Chaotropic Agents
Density: 1.345 g/cm³ at 20 °C (Lit.)
Melting Point: 180-190 °C
UV/Visible Absorbance: OD260nm (6.0 M aq soln) <0.03
Presentation: White Crystalline Powder
pH: 4-6 (6.0 M aq soln)
Solubility: Soluble in water,Clear, Colorless Solution (6 M - clear, colorless solution).
Storage & Handling: Room Temperature, desiccate

Supplier: THERMO MATRIX TECHNOLOGIES

Easy Pierce, Microplate seal for ALPS 3000, Heat sealing film/foil/tape (96/384 wells), Roll, Foil, Easy Pierce seal, for PP and PE microplates, Pierceable

Supplier: Hach

Bottle Cap, with inert Teflon® liner for mixing bottle, pk/12 1 * 12 items

Supplier: OMEGA BIO-TEK

E.Z.N.A.® Fastfilter® Plasmid kits rapidly purify plasmid DNA utilising lysate clearance filter syringes, whilst E-Z 96® Fastfilter Plasmid kits employ lysate clearance plates in a 96-well format. Fastfilter® kits allow midi- and maxi-scale plasmid isolation in less than 40 m.

Supplier: VITLAB

Volumetric flask, PMP, class B, with screw cap, PP, 500 mL 1 * 2 items