106022 Results for: "B581&pageNo=25&view=list"

Supplier: ProSci Inc.

SERPINE2 is also known as Glia-derived nexin (GDN), Peptidase inhibitor 7 (PI7), Protease nexin 1(PN1). SERPINE2 is a secreted glycoprotein which belongs to the serpin family. SerpinE1 is the primary physiological inhibitor of the two plasminogen activators urokinase (uPA) and tissue plasminogen activator (tPA). PAI-1 / GDN is also implicated in adipose tissue development. It suggests that PAI-1 inhibitors serve in the control of atherothrombosis. Defects in Serpin E1 / PN1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency) which is characterized by abnormal bleeding due to SerpinE1 defect in the plasma.

Supplier: VWR Collection

These portable, economical meters can simultaneously measure conductivity, specific conductance, salinity, TDS (Total Dissolved Solids) and temperature.

Supplier: Bioss

GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.

Supplier: Bioss

Calcium signaling in mitochondria is important in order for it to function in response to a variety of extracellular stimuli. Signaling begins with Ca(2+) entry in mitochondria via the Ca(2+) uniporter followed by Ca(2+) activation of three dehydrogenases in the mitochondrial matrix. ARALAR, the neuronal Ca(2+)-binding mitochondrial aspartate-glutamate carrier, has Ca(2+) binding domains facing the extramitochondrial space and functions in the malate-aspartate NADH shuttle (MAS). ARALAR is encoded by the SLC25A12 gene and is expressed in brain and skeletal muscle. ARALAR is required for the synthesis of brain aspartate and N-acetylaspartatemay and plays a role in myelin formation. It is also essential for the transmission of small Ca(2+) signals to mitochondria via an increase in mitochondrial NADH. In addition, ARALAR is implicated in conferring susceptibility to schizophrenia.

Supplier: VWR Collection

Designed for freezing samples in all cryopreservation applications, these vials feature an internal thread with washer, or an external thread.

Supplier: SIGMA ALDRICH MICROSCOPY

ANSA (8-Anilino-1-naphthalenesulfonic acid) is a hydrophobic polarity sensitive fluorescent dye useful as a site probe to detect conformational changes in cell and micelle membranes and molecules such as proteins. ANSA is also used as a fluorescent probe for the estimation of the critical micelle concentration (CMC) of surfactants.

Supplier: SIGMA ALDRICH MICROSCOPY

3-(2-Pyridyl)-5,6-di(2-furyl)-1,2,4-triazine-5′,5′′-disulfonic acid disodium salt, also known as Ferene, is commonly used to measure the concentration of iron ions in aqueous solutions. The reagent is sensitive to ferrous iron ions (Fe2+) and forms a purple-colored complex with these ions in the presence of a reducing agent. The intensity of the purple color formed is proportional to the concentration of iron ions present in a solution and is quantified spectrophotometrically.

Supplier: 3M

3M™ Aura™ Particulate Respirators 9300+ Series has an ergonomic, flat-fold, 3-panel design featuring a low breathing resistance filter media. Available in FFP1, FFP2, and FFP3 protection levels, and with valved and unvalved models, these respirators feature an innovative chin tab for easy adjustments and an embossed, sculpted upper panel to help reduce eyewear fogging.

Supplier: Thermo Fisher Scientific

trans-1,2-Diaminocyclohexane-N,N,N',N'-tetraacetic acid monohydrate 97.5-100.5% ACS

Supplier: Bioss

The protein encoded by this gene is a member of theTNF-receptor superfamily. This receptor is expressed preferentiallyin the tissues enriched in lymphocytes, and it may play a role inregulating lymphocyte homeostasis. This receptor has been shown tostimulate NF-kappa B activity and regulate cell apoptosis. Thesignal transduction of this receptor is mediated by various deathdomain containing adaptor proteins. Knockout studies in micesuggested the role of this gene in the removal of self-reactive Tcells in the thymus. Multiple alternatively spliced transcriptvariants of this gene encoding distinct isoforms have beenreported, most of which are potentially secreted molecules. Thealternative splicing of this gene in B and T cells encounters aprogrammed change upon T-cell activation, which predominantlyproduces full-length, membrane bound isoforms, and is thought to beinvolved in controlling lymphocyte proliferation induced by T-cellactivation. [provided by RefSeq, Jul 2008].

Supplier: Bioss

GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.

Supplier: ALSICO HIGHTECH

These cleanroom coveralls are made of Alsistrong® (98% polyester and 2% carbon). Suitable for the highest cleanroom classes ISO 4 to 9 or GMP classes A to D.

Supplier: PIERCAN

Black EPDM (Ethylene Propylene Diene Monomer) sleeve. Excellent chemical properties, good mechanical properties. Composition in accordance with the FDA positive list (CFR 21 § 177.2600).

Supplier: MP Biomedicals

Adenosine 5'-triphosphate (ATP) disodium salt hydrate is a multifunctional nucleotide, which is essential in a variety of cellular functions.

Supplier: MP Biomedicals

Proteinase K is a highly active stable endopeptidase with a broad spectrum of action was isolated by E. Merk's Darmstadt Biochemical Research Department in 1970 from a culture filtrate of the fungus, Tritirachium album Limber. This fungus is able to grow on Keratin (e.g., wool, horn particles) as the sole source of carbon and nitrogen. The isolated protease was, therefore, given the K designation.
Proteinase K is a stable and highly reactive serine protease. Evidence from crystal and molecular structure studies indicates the enzyme belongs to the subtilisin family with an active-site catalytic triad (Asp39-His69-Ser224). It is stable in a broad range of environments: pH, buffer salts, detergents (SDS), and temperature. In the presence of 0,1 to 0,5% SDS, proteinase K retains activity and will digest a variety of proteins and nucleases in DNA preparations without compromising the integrity of the isolated DNA.

Supplier: SIOEN

Multifunctional jacket with detachable sleeves and fur lining. The jacket is made of 60% polyamide and 40% cotton. With stitched seams.

Supplier: Thermo Fisher Scientific

di-Potassium oxalate monohydrate 99% ACS

Supplier: Thermo Fisher Scientific

1-Octanesulphonic acid sodium salt monohydrate 98%

Supplier: HAKRO

Poloshirts, Poloshirt, Hakro, 802, L, Polyester/cotton, Grey, For men, Polyester/cotton, Weight: 200 g/m², General Purpose, Pockets: With pockets, Closure type: Buttons

Supplier: FRISTADS KANSAS

Working trousers made of FAS®, Fristads best navy twill manufactured from 100% cotton.

Supplier: Avantor

Avantor® ACE® UltraCore SuperPhenylHexyl solid-core (core-shell) particle columns are ideal for demanding MS work offering improved MS signal intensity and maximum MS response. These stainless steel columns combine high efficiency separations with low column back pressure. The Encapsulated Bonding Technology (EBT™) greatly increases the ligand coverage of the silica surface and effectively eliminates the effect of unbonded silanol groups on separations. This higher ligand coverage results in improved inertness, chromatographic performance and stability.

Supplier: Avantor

The Avantor® ACE® Excel® C18-AR phase utilises a specially developed ligand combining a C18 chain with integral phenyl functionality, thus combining the benefits of both C18 and phenyl characteristics into a single phase. This can be used for ‘standard’ C18 column separations, but is additionally recommended for separations that involve compounds containing aromatic functionality.

Supplier: MACRON AVANTOR BRAND

tri-Sodium citrate dihydrate ≥99.0%, crystals, AR® ACS, Macron Fine Chemicals™

Supplier: Avantor

Avantor® ACE® HILIC-A columns have been designed specifically for HILIC applications and are especially useful for the separation of polar analytes. These columns are part of a suit of 3 proprietary HILIC columns (HILIC-A, HILIC-B and HILIC-N) developed to enable chromatographers to achieve reproducible and successful HILIC separations using a systematic approach to method development.

Supplier: VWR Collection

User friendly instrument, with articulated electrode stand and IP 43-rated housing, provides high resolution and accuracy for precise multi-parameter measurements. This meter can either measure pH/mV and conductivity or pH/mV and oxygen simultaneously. Complete with USB output for connection to a computer. GLP compliant.

Supplier: USP

USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

Supplier: GRANT INSTRUMENTS

Digital unstirred water bath range with choice of models from 5 to 26 litres. All units have stainless steel tanks and durable painted steel cases, offer fast heat-up times, good temperature control, front panel lock, easy to use controls and a bright, clear display. All baths have heater mat technology ensuring optimum working space, without a heating element in the tank they are easier to clean. 12 litre and larger models feature a convenient drain tap on the front of the bath. The range is ideal for use in education as well as industrial applications such as product and materials testing.

Supplier: Apollo Scientific

An aminoglycoside antibiotic with bactericidal activity

Supplier: USP

USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

Supplier: SIGMA ALDRICH MICROSCOPY

Acridine orange hemi (zinc chloride) salt has been used to stain primary human umbilical vein endothelial cells (HUVEC) and is used in micronucleus tests (MNTs). Acridine orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine orange dye has been used to analyse mitochondria and lysosomal content by flow cytometry, characterise multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.