Supplier: STEMCELL Technologies

Leukemia inhibitory factor (LIF) is an interleukin 6 class cytokine that regulates a broad variety of developmental functions. After LIF binds to the LIF receptor (LIFR), LIFR associates with gp130 and activates JAK/STAT and MAPK signaling (Auernhammer and Melmed; Suman et al.). LIFR activation of STAT3 is essential for maintaining the mouse embryonic stem cell phenotype (Niwa et al.). Produced by the endometrium, LIF plays an important autocrine and paracrine role in implantation by regulating proliferation, invasion, and differentiation of trophoblasts following blastocyst attachment (Auernhammer and Melmed; Suman et al.). Human LIF can be used for the maintenance of mouse embryonic stem cells; however, mouse LIF cannot bind to the human receptor, thus rendering mouse LIF inactive (Dahéron et al.). LIF is produced by CD4+ and activated regulatory T cells, and promotes Foxp3 expression, while repressing Th17 lineage-specific genes (Metcalfe). LIF is also secreted by mesenchymal stromal cells, where it supports hematopoiesis and immune modulation (Nasef et al.).

Supplier: TOSOH Bioscience

COLUMN TSKGEL GUARD SUPERHZ-H 10µM 1 * 1 items

Supplier: Abnova

Recombinant protein, gpr55 (np_005674.2) recombinant protein without tag. 1 * 2 µG

Supplier: STEMCELL Technologies

The platelet-derived growth factor (PDGF) family has five heparin-binding members that assemble into four homodimers (PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD) and one heterodimer (PDGF-AB; Fretto et al.; Li and Eriksson). PDGF signals through the receptor tyrosine kinases PDGFRα and PDGFRβ. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin, such as fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). PDGF-DD promotes growth and survival of renal artery smooth muscle cells and lens epithelial cells, and can act as a macrophage chemoattractant (Changsirikulchai et al.; Lokker et al.; Ray et al.; Uutela et al.).

Supplier: STEMCELL Technologies

Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda et al.). GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 cells (Francisco-Cruz et al.). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton et al.). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz et al.).

Supplier: CHIRAL TECHNOLOGIES

COLUMN CHIRALPAK WH 250X4.6MM 10µM 1 * 1 items

Supplier: Merck

KREBS-HENSELEIT BUFFER MODIFIED, WITH 2000 MG/L GLUCOSE, WITHOUT CALCIUM CHLORIDE AND SODIUM BICARBONATE. CELL CULTURE 1 * 1 Each

Supplier: TRESTON

Middle plate 90-130/100 L=100 1 * 1 items

Supplier: Abnova

Recombinant protein, pcdhgc5( np_115783.1, 1 a.a. - 878 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, dgat2( np_115953.2, 1 a.a. - 388 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: DELTA T

BlueLineBox 10L with 1 x -30 DEG TEMPSHELL and 2.5 TEMPFRAMES 1 * 1 items

Supplier: MBV

LID 300HOLES EDGE PROT. F/MAS 100ISO/NT 1 * 1 items

Supplier: DWK Life Sciences

BLOCK HEATING ALUMINUM 14/10KITS 1 * 1 items

Supplier: Abnova

Recombinant protein, foxo3( aah20227.1, 1 a.a. - 673 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: DELTA T

BlueLineBox 10L with 1 x 22 DEG TEMPSHELL and 2.5 TEMPFRAMES 1 * 1 items

Supplier: Abnova

Recombinant protein, vps52( np_542131, 625 a.a. - 723 a.a.) partial recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cblb( aah32851.1, 1 a.a. - 982 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, camk2g( aah34044, 1 a.a. - 528 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, kcnmb2( aah17825, 1 a.a. - 236 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, lect1( np_008946.1, 1 a.a. - 334 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, wdr5( np_060058, 16 a.a. - 120 a.a.) partial recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, pdia6( aah01312, 1 a.a. - 441 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cldn1( aah12471.1, 1 a.a. - 212 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, cldn10( np_008915.1, 1 a.a. - 228 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, atp6v1a( aah13138, 1 a.a. - 618 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, pcdh8( aah36025.1, 1 a.a. - 1070 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: Abnova

Recombinant protein, trim34( np_569073.1, 1 a.a. - 243 a.a.) full-length recombinant protein with gst tag. 1 * 2 µG

Supplier: REAGECON

Turbidity standard Non Ratio 10NTU 1 * 100 mL

Supplier: SAMCO

PASTEUR PIPETTE 7,7 mL, POLYETHYLENE 1 * 500 items

Supplier: HIRSCHMANN

Suction tube . 400 mm for em-dispenser up to 10ml 1 * 1 items