112019 Results for: "AnalaR+NORMAPUR&pageNo=10&view=list"

Supplier: Thermo Scientific

ANGLE 1 * 1 items

Supplier: Thermo Fisher Scientific

CYLINDER 1 * 1 items

Supplier: CELLPATH

[EN]OMNISTOR WHEELED BASE PLINTH CELLPAT 1 * 1 ST

Supplier: Roth Carl

Rotilabo-storage box 1 * 5 items

Supplier: Ambion

Yeast tRNA 1 * 0,5 ml

Supplier: LGC Standards PROMOCHEM

CRM VAPOUR PRESSURE ASTM D5191 104.4 KPA 1 * 100 mL

Supplier: MARKET SOURCE PART PROCESS

X6 PS NIST 10UM 3000/ML 25ML 1 * 6 items

Supplier: Thermo Fisher Scientific

For customers in cell and gene therapy and vaccine production, the CryoMed with OPC UA provides precise, repeatable freezing results that protect samples from intracellular freezing. The CryoMed features OPC UA serial communication (ethernet) capabilities, comes standard factory certifications, provides enhanced data traceability via a touch screen user interface and offers customizable freezing profiles while supporting 21 CFR part 11 and GMP needs.

Supplier: ProSci Inc.

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulphide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important homeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens. IL-2 promotes T cell proliferation and particularly naive T cells. IL-2 signalling on activated T cells is effected through a quaternary high-affinity receptor complex consisting of IL-2, IL-2Ralpha (CD25), IL-2Rbeta and IL-2Rgamma. Naive T cells are relatively insensitive to IL-2 as they only express small amounts of IL-2Rbeta and IL-2Rgamma. They only acquire sensitivity after CD25 expression, which captures the cytokine and presents it to the IL-2Rbeta and IL-2Rgamma receptors. IL-2 Superkine (Fc) is an artificial variant of IL-2 containing mutations at positions L80F / R81D / L85V / I 86V / I92F. These mutations are located in the molecule's core that acts to stabilize the structure and to give it a receptor-binding conformation mimicking native IL-2 bound to CD25. These mutations effectively eliminate the functional requirement of IL-2 for CD25 expression and elicit proliferation of T cells. Compared to IL-2, the IL-2 superkine induces superior expansion of cytotoxic T cells, leading to improved antitumor responses in vivo, and elicits proportionally less toxicity by lowering the expansion of Tregulatory cells and reducing pulmonary oedema.

Supplier: ProSci Inc.

Receptors for the Fc region of immunoglobin G (Fc gamma R) are divided into three classes and Fc gamma RIII is a multifunctional, low/intermediate affinity receptor. In humans, Fc gamma RIII is expressed as two distinct forms (Fc gamma RIIIA and Fc gamma RIIIB) that are encoded by two different but highly homologous genes in a cell type-specific manner. Fc gamma RIIIB is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas Fc gamma RIIIA is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages. The Fc gamma RIIIA receptor is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), mast cell degranulation, and clearance of immune complexes. Fc gamma RIIIA has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and delivers an activation signal in the immune responses. Aberrant expression or mutations in this gene is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. In humans, it is a 50 -70 kD type I transmembrane activating receptor. The Fc gamma RIIIA cDNA encodes 254 amino acid including a 16aa signal sequence, 191 amino acid ECD with two C2-type Ig-like domains, five potential N-glycosylation sites, a 22 amino acid transmembrane sequence and a 25 amino acid cytoplasmic domain.

Supplier: Portwest

A highly innovative and functional jacket that provides seven wearer combinations. This extremely versatile jacket is highly adaptable to all weather conditions and is certified to the highest in waterproof and breathable standards.

Supplier: Amarell

Density hydrometer, 1,100-1,200:0,001g/cm , ref. temp. 20C, with therm., 0+40:1C, 350mm long, special liquid 1 * 1 items

Supplier: PURITAN MEDICAL

SWAB NON-STERILE COTTON TIP 15.2CM LENGT 1 * 10.000 items

Supplier: Amarell

Density hydrometer, 1,200-1,400:0,002g/cm , ref. temp. 20C, with therm., 0+40:1C, 350mm long, special liquid 1 * 1 items

Supplier: CHEMetrics

GLYCOL TEST KIT 1 * 1 items

Supplier: Roth Carl

Rack inserts for Multibox 1 * 5 items

Supplier: OMEGA BIO-TEK

E-Z® 96 DNA plates are silica glass fibre plates can bind up to 50 μg of genomic DNA or 20 μg of plasmid DNA per prep. Each well has a capacity of 1 ml and the plates are semi skirted. E-Z 96 DNA plates can be processed in vacuum manifolds and/or by centrifugation.

Supplier: Restek

[EN]RXI-LAO COLUMN 40 MX0.18MM IDX1.0µM 1 * 1 ST

Supplier: LINKER INDUSTRIE TECHN

Reagenzglasgestell, Fachanzahl 4 x 12, Gestellhöhe 100 mm aus Edelstahl, rostfrei, elektrochemisch poliert mit 2 Facheinteilungen, Boden aus Schweißgitter w 8 mm Fachgröße 18 x 18 mm (bis Ø 16 mm) 1 * 1 ST

Supplier: Corning

10µl Pre-Sterilized Hamilton CO-RE Style Liquid Level Sensing Filter Tip. 96 Tips per Rack, 5 Racks/pack, 12 packs/case 1 * 5.760 items

Supplier: Thermo Fisher Scientific

Use performance level 1 Thermo Scientific™ SureSTART™ 2 ml glass screw top vials for everyday chromatography analysis. They provide an affordable choice and can be used with all GC and HPLC/UHPLC instrument types. These 2 ml glass screw top vials are specification certified to ensure autosampler compatible physical dimensions. Choose from clear and amber glass. The vials meet all requirements of US, EU, and JPN Pharmacopia. Seal these screw top vials with 9 mm screw caps and septa.

Supplier: STEMCELL Technologies

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang et al.; Dorssers et al.; Broughton et al.). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton et al.). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock et al.). This product is animal component-free.

Supplier: Portwest

The DX4 winter jacket uses dynamic stretch and highly insulating fabric that guarantees warmth and comfort. The ergonomic profile and raglan sleeves allow for an unrestricted range of motion and greater freedom of movement. Its longer back length, wind cuffs, and adjustable hood provide extra protection against the elements.

Supplier: STEMCELL Technologies

Interleukin 1 beta (IL-1β) is synthesized as an inactive precursor protein or pro-IL-1β. This precursor is cleaved intracellularly by caspase 1 (IL-1β convertase) to form the active form of the protein that is later secreted (Allan et al.). IL-1β binds to IL-1 receptor and activates intracellular signaling via the MAPK or NF-κB pathway. IL-1β is released by monocytes, tissue macrophages, and dendritic cells in response to infection or injury and induces expression of acute-phase proteins. It also promotes the infiltration of inflammatory and immunocompetent cells from the circulation into the extravascular space and affected tissues, by stimulating the expression of adhesion molecules on endothelial cells. IL-1β also affects other immune cells; for example, it co-stimulates T cell functions together with an antigen or mitogen. It also stimulates Th17 differentiation and B cell proliferation in an IL-6-dependent manner.

Supplier: Portwest

Contemporary work trouser made from highly durable ripstop fabric that stretches as you move. Subtle articulation on the knees allow for increased freedom of movement and a high rise back waistband ensures protection in all working positions. Packed with functionality including pre-bent knees, a crotch gusset, two tier knee pad pockets and an adjustable leg length for added convenience.

Supplier: TECHNI GLOVE

Nitrile GL30cmTechniGlove TN1204Wtacky 1 * 1.000 items

Supplier: AGILENT

BL21 competent cells are an all-purpose strain for high-level protein expression and easy induction.

Supplier: EPPENDORF

Eppendorf Fast PCR tube strips made of polyethylene transfer heat faster than tubes made of traditional plastics. The Fast PCR tube strips are particularly suited to scientists using Fast PCR reagent kits, scientists trying to speed up protocols or cyclers with high heating and cooling rates.

Supplier: Ambion

Poly(A+)Mouse Embryo RNA 1 * 5 µG

Supplier: CHRIST MARTIN

ROTOR F/48X10-12-15ML F/RVC 2-33 1 * 1 ST