145484 Results for: "Ampoule+Openers&pageNo=16"

Supplier: Merck

1,3-Dimethylnaphthalene, Sigma-Aldrich®

Supplier: Merck

1,3-Dicyclohexylurea, Sigma-Aldrich®

Supplier: AAT BIOQUEST

N-BOC-cadaverine is a monoprotected diamine that is widely used as a building block in bioconjugate chemistry.

Supplier: HARTMANN PAUL

Non-sterile gauze swabs with folded-in cut edges.

Supplier: MP Biomedicals

Sephadex is a beaded gel filtration medium prepared by cross-linking dextran with epichlorohydrin under alkaline conditions.

Supplier: Merck

1,4-Dichlorobenzene-[D₄], Sigma-Aldrich®

Supplier: Merck

(±)-1,2-Propanediol, Sigma-Aldrich®

Supplier: Welch by Gardner Denver

Drum pump accessory, Foot switch complete for Biovac

Supplier: FRITSCH

Sieve inserts determine the final fineness of a sample. These sieve inserts are available with trapezoidal or square perforations.

Supplier: Molekula

1,1-Bis(methylthio)-2-nitroethylene

Supplier: Thermo Scientific

1,3-Bis(methylthio)-2-propanol

Supplier: Merck

1,2-Diiodoethane, Sigma-Aldrich®

Supplier: Merck

1,2-Difluorobenzene, Sigma-Aldrich®

Supplier: Merck

1,3-Dioxane, Sigma-Aldrich®

Supplier: Merck

1,2-Diiodotetrafluorobenzene, Sigma-Aldrich®

Supplier: Merck

1,7-Phenanthroline, Sigma-Aldrich®

Supplier: Merck

(±)-1,5-Hexanediol, Sigma-Aldrich®

Supplier: Merck

1,2-Epoxybutane, Sigma-Aldrich®

Supplier: Merck

1,2-Diphenoxyethane, Sigma-Aldrich®

Supplier: Merck

10-Methylphenothiazine, Sigma-Aldrich®

Supplier: THERMO NATIONAL SCIENTIFIC

These PP caps are chemically inert and suitable for most chromatography applications.

Supplier: Thermo Fisher Scientific

1,2-Dichloroethane ≥99% for HPLC

Supplier: STEMCELL Technologies

Interleukin 15 (IL-15) is a four-alpha helix bundle cytokine with many similar properties to IL-2, with which it shares components of its receptor. The IL-15 receptor is a heterotrimeric receptor composed of IL-15Ra, the high-affinity receptor for IL-15, as well as IL-2/15Rb (CD122) and common gamma chain (CD132). IL-15 binds to IL-15Rα receptor and can then be presented in trans to IL-2/15Rb and common gamma chain on other cells. Trans-presentation is thought to be the major mechanism by which IL-15-mediated responses occur in mice, although may not be necessary in humans (Castillo et al.). The cytoplasmic domains of IL-2/15Rb and common gamma chain mediate signaling to activate JAK/STAT and PI3K pathways. IL-15 supports the survival and proliferation of naive CD4+ and CD8+ T cells, and promotes homeostasis of memory T cells. IL-15 also promotes the survival and differentiation of NK cells and regulates their cytolytic activity (Ma et al.).

Supplier: Edmund Bühler GmbH

Shaker, Rocking/Rotating Shaker

Supplier: Thermo Fisher Scientific

Vitamin A palmitate, 1.7 MIU/g

Supplier: Thermo Fisher Scientific

13-cis-Retinoic acid

Supplier: MACHEREY-NAGEL

These snap ring vials with quick, convenient sealing method can be used on all common HPLC autosamplers.

Supplier: STEMCELL Technologies

Interleukin 12 (IL-12p70) is a heterodimeric cytokine composed of p35 and p40 subunits. IL-12 is produced by monocytes, macrophages, dendritic cells, neutrophils, and B cells in response to bacterial products and cytokines such as IFN-γ. The IL-12 receptor is expressed on T, NK, and dendritic cells. Upon binding, IL-12 initiates signaling via the JAK/STAT signaling pathway and stimulates NK, B, and T cells to produce IFN-γ (Watford et al.). It also regulates cytokine synthesis, proliferation of T and NK cells, and stimulates differentiation of CD4+ and CD8+ T cells (Germann and Rüde). Mice that are deficient in IL-12 are susceptible to many intracellular pathogens and have impaired IFN-γ secretion, Th1 differentiation, and NK cytolytic activity; however, Th2 development and IL-4 production are enhanced (Watford et al.).

Supplier: STEMCELL Technologies

Interleukin 13 (IL-13) is a cytokine important in type 2 immune responses and is expressed by T helper type 2 (Th2) cells and group 2 innate lymphoid cells (ILC2s) (Pulendran and Artis). IL-13 binds a receptor composed of IL-4Ra and IL-13Ra1 or IL-13Ra2 (Wynn 2003). IL-13 receptor is expressed on B cells and promotes B cell proliferation, induces class switching to IgG4 and IgE, and functions in the recruitment and activation of IgE-producing B cells (Hershey). The receptor is also expressed on basophils, eosinophils, mast cells, endothelial cells, fibroblasts, monocytes, macrophages, respiratory epithelial cells, and smooth muscle cells (Hershey). Signaling through the IL-13 receptor activates the JAK/STAT and IRS-1/IRS-2 pathways. in vivo, IL-13 has a role in resistance to extracellular helminth parasites by regulating gastrointestinal parasite expulsion, as well as in airway hyperresponsiveness, allergic inflammation, tissue remodeling, tumor cell growth, and fibrosis (Wynn 2015). Secreted IL-13 is a protein consisting of 112 amino acids with a molecular mass of 10 kDa (Hershey). Human IL-13 is not species-specific but has greater activity on human cells compared to mouse cells (Hershey).

Supplier: AAT BIOQUEST

Pluronic® F-127 is a nonionic surfactant that is 100% active and relatively non-toxic to cells, and frequently used with dye AM esters to improve their water solubility.