30586 Results for: "6-Bromo-2-chlorobenzothiazole&pageNo=20&view=easy"

Nerve growth factor (NGF)-beta is a prototypical member of the neurotrophin family and has a role in the survival and growth of neural cells, regulating cell growth, promoting differentiation into neurons, and neuron migration. The beta subtype of NGF is biologically active in comparison to the alpha-2 and gamma-2 subtypes. NGF-beta in its secreted form can bind to tyrosine kinase A (TrkA) receptor with high affinity and to p75 (NTR) with low affinity (Levi and Alemà; Sofroniew et al.). NGF has been shown to possess pro-inflammatory and pro-fibrogenic properties (Micera et al.). It has also been shown that overexpression of NGF-beta promotes differentiation of bone marrow mesenchymal stem cells into neurons through regulation of AKT and MAPK pathways (Yuan et al.).

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CANNON CALIBRATIEOLIE N14 1 * 500 mL

Supplier: CANNON INSTRUMENT

CANNON CALIBRATIEOLIE N14 1 * 500 mL

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CRYOTUBE BOX 100 PLACES RED 1 * 1 items

Supplier: DELTALAB

CRYOTUBE BOX 100 PLACES RED 1 * 1 items

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INDICATOR SOLUTION 5-100 MG/L HARDNESS 1 * 500 mL

Supplier: Hach

INDICATOR SOLUTION 5-100 MG/L HARDNESS 1 * 500 mL

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Storage cabinet, extension 100/60/200,blue 1 * 1 items

Supplier: TRESTON

Storage cabinet, extension 100/60/200,blue 1 * 1 items

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Storage cabinet, extension 100/50/200 ,blue 1 * 1 items

Supplier: TRESTON

Storage cabinet, extension 100/50/200 ,blue 1 * 1 items

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T3 RNA Polymerase Plus 1 * 1 KIT

Supplier: Ambion

T3 RNA Polymerase Plus 1 * 1 KIT

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Eith Self-Securing Adjustment Left 1 * 1 items

Supplier: Retsch GmbH

Eith Self-Securing Adjustment Left 1 * 1 items

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HYDROMET W THERM 0,900-0,950 0,0005 20C 1 * 1 items

Supplier: GERING

HYDROMET W THERM 0,900-0,950 0,0005 20C 1 * 1 items

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T3 RNA Polymerase Plus 1 * 1 KIT

Supplier: Ambion

T3 RNA Polymerase Plus 1 * 1 KIT

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T7 RNA Polymerase Plus 1 * 1 KIT

Supplier: Ambion

T7 RNA Polymerase Plus 1 * 1 KIT

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Mouse Recombinant TNF-alpha

Supplier: STEMCELL Technologies

Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine that activates NF-κB, MAPK, and PI3K/AKT pathways. Activated T cells and macrophages are the primary producers of TNF-α in response to inflammation and infectious conditions. Many other cell types have been shown to produce TNF-α, among them B cells, NK cells, mast cells, neutrophils, dendritic cells, microglia, endothelial cells, smooth muscle cells, cardiomyocytes, and fibroblasts. TNF-α has cytotoxic effects on cancer cells in vitro by stimulating anti-tumor immunosuppressive responses. TNF-α stimulates expression of E- and P-selectins, thus facilitating adhesion of neutrophils, monocytes, and memory T cells to activated platelets and endothelial cells (Zelová andamp; Hosek). Other effects of TNF-α include vasodilatation and edema formation.