32315 Results for: "5-Methoxynicotinic+acid&pageNo=20"

Supplier: Air Liquide

CRYOTANK ARPEGE 70,2ML RACKS,LEVEL 1 * 1 item

Supplier: Biotium

MINI SUPER HT PAP PEN2 1 EA 1 * 1 Each

Supplier: TRESTON

Storage system 100/30/200 light grey,Standard part 1 * 1 items

Supplier: SARSTEDT

2ml Autoanalyser Sample Cups for Hitachi Analysers (Polystyrene) 38x17mm 1 * 5.000 items

Supplier: STEMCELL Technologies

Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda et al.). GM-CSF was first purified from the culture of mouse lung tissue after lipopolysaccharide treatment. GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 cells (Francisco-Cruz et al.). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton et al.). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz et al.).

Supplier: MACHEREY-NAGEL

POLYGRAM CEL 300 DEAE, 5x20 cm 1 * 50 items

Supplier: TRESTON

Storage system 100/60/200 light grey,Standard part 1 * 1 items

Supplier: TRESTON

Storage system 100/40/200 light grey,Standard part 1 * 1 items

Supplier: DWK Life Sciences

SEPTUM 18MM BUTYL PTFE VIAL 1 * 100 items

Supplier: DWK Life Sciences

SCREW CAP WITH PTFE GASKET 1 * 100 items

Supplier: Alpha Laboratories

PASTEUR PIPETTE MICRO, LARGE BULB, STER/ 1 * 200 items

Supplier: Merck

NIST PATTERN OF GASOLINAS TYPE PATTERNS 1 * 40 mL

Supplier: Air Liquide

CRYOTANK ARPEGE 70,2ML RACKS,TEMP,LEVEL 1 * 1 item

Supplier: HIRSCHMANN

VOL.FLASK 20ML NS10/19 A HOLLOW GLASS 1 * 2 items

Supplier: Air Liquide

CRYOTANK ARPEGE 70,2ML RACKS 1 * 1 item

Supplier: witeg Labortechnik

TEST TUBES, BORO-SILICATE GLASS, ROUND BOTTOM, ST19/26, 150X20MM 1 * 1 items

Supplier: Air Liquide

ARPEGE 70 + 2ml racks + level + automatic filling 1 * 1 item

Supplier: MARIENFELD

COVER GLASS PRECISION Ø20MM 1.5H 2-PART 1 * 1.000 items

Supplier: B. Braun

ORIGINAL PERFUSOR-SYRINGE 20ML WITHOUT SUCTION NEEDLE 1 * 50 items

Supplier: Merck

BOVINE SERUM ALBUMIN, NON-ACETYLATEDAQUE OUS SOLUTI 1 * 1,25 mL

Supplier: BUCHI

100x Glass Tubes 20ml for FC60 1 * 100 items

Supplier: STEMCELL Technologies

Midkine is a member of a unique family of heparin-binding growth factors that are structurally different from other fibroblast growth factors (Muramatsu; Takada et al.). Midkine is a proinflammatory cytokine, promoting the migration of leukocytes, fibrinolysis, and acting as a chemotactic agent towards neutrophils (Muramatsu; Said et al.; Takada et al.). It also regulates growth, differentiation, and development during the midgestion stage of embryogenesis, and promotes angiogenesis (Muramatsu; Said et al.; Takada et al.). The protein structure consists of three antiparallel β-sheets and is highly conserved between species (Muramatsu; Takada et al.). While the exact signal pathway is not known, proposed pathways include promoting LRP, inhibiting Src kinase, activating paxillin and STAT1α, activating PI2 and MAP kinases, suppressing caspases, binding to α6β1-integrin and tetraspanin, activating FAK, phosphorylating STAT3, suppressing STAT5 phosphorylation, activating ALK, activating PI3 kinase and transcription of NFkB, binding to neuroglycan C or nucleolin, and binding to eIF3 (Muramatsu). In cultured cells, midkine influences growth and survival of neural precursor cells, synthesis of cytokines from endothelial and renal epithelial cells, and promotes synthesis of extracellular matrices from fibroblasts (Muramatsu; Takada et al.).

Supplier: Heidolph Instruments GmbH & Co.KG

Toroidal transformer 2x115V/2x(2x15V) 20VA (PD 51xx/52xx) 1 * 1 items

Supplier: SARSTEDT

MINI REDON SET 20ML RESERVOIR FLAT DRAIN CHAMBER 6 WITH CONNECTED GUIDING NEEDLE 1 * 80 items

Supplier: Brand

Micro-weighing container inclusive 10 filters and 3 cover caps 1 * 1 items

Supplier: STEMCELL Technologies

Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda et al.). GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 T cells (Francisco-Cruz et al.). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton et al.). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. Recombinant human GM-CSF (rhGM-CSF) promotes the production of myeloid cells of the granulocytic (neutrophils, eosinophils and basophils) and monocytic lineages in vivo. It has been tested for mobilization of hematopoietic progenitor cells and for treating chemotherapy-induced neutropenia in patients. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz et al.).

Supplier: Air Liquide

ARPEGE 70 + 2ml racks +temp+ level + automatic filling 1 * 1 item

Supplier: 3M

3M™ SecureFit™ Safety Helmet, X5000 series, provides secure, comfortable, and adjustable head protection for workers in a variety of situations. The helmets feature six different settings to adjust positions and 4-point chin strap selector systems to switch between EN 397 (industrial safety helmets) or EN 12492 (helmets for mountaineers) certification standards. X5000 series safety helmets are vented, brimless, and have 3M™ UVicator™ sensors that indicate levels of exposure to damaging ultraviolet (UV) light. The easily-adjustable, 6-point ratchet suspension system features the exclusive 3M™ pressure diffusion technology.

Supplier: STEMCELL Technologies

Ciliary neurotrophic factor (CNTF) is a neurotrophic factor that belongs to the four-helix bundle cytokine family and is structurally related to interleukin 6 (IL-6), interleukin 11 (IL-11), leukemia inhibitory factor (LIF), and oncostatin M (OSM). CNTF binds to its receptor CNFTRα and induces formation of a heterodimer of the signal transducing IL-6 receptor gp130 and LIF receptor (LIFR)-β, which triggers JAK/STAT, ERK, and PI3K signaling cascades (Schuster et al.). CNTF plays an important role in neurogenesis and the differentiation of neural stem cells and has been suggested to possess a therapeutic role in treating neurological disorders (Ding et al.; Oppenheim et al.). CNTF has also been shown to protect rod photoreceptors from light-induced damage and have therapeutic effects on retinal degenerative diseases caused by genetic defect or damage induced by toxins, autoantibodies, or strong light (Pernet et al.; Rhee et al.). Another therapeutic role of CNTF has been reported in protecting oligodendrocytes from death induced by apoptosis (Louis et al.). Additionally, CNTF is commonly used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into astrocytes (Krencik and Zhang). This product is animal component-free.

Supplier: HIRSCHMANN

VOL.FLASK 20ML NS10/19 AMBER POLYSTOPP A 1 * 1 items