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Anti-SPG11 Rabbit Polyclonal Antibody

Anti-SPG11 Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

SPG11 Antibody: Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders.  Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia (cHSP) in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration. Mutations of the SPG11 gene encoding the spatacsin protein have been identified as a major cause of HSP-TCC. Spatacsin is a potential transmembrane protein that is phosphorylated upon DNA damage. It is expressed in all structures of the brain, with a high expression in the cerebellum. SPG11 mutations may occur more frequently in familial than sporadic forms of cHSP without TCC. Kjellin syndrome is found to be associated with mutations in not only the SPG15 gene but also SPG11 gene.  Recent studies show Parkinsonism may initiate SPG11-linked HSP TCC and that SPG11 may cause juvenile Parkinsonism.

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Jackets, Hi-vis long jacket, Jackets, Orbit, XXL, Gore-Tex®, Hi-vis orange, For men, 2-layer Gore-Tex® Benbecula fabric, HiVis, Cold, Outdoor, Pockets: With pockets, Closure type: Press studs / snaps

Jackets, Hi-vis long jacket, Jackets, Orbit, XXL, Gore-Tex®, Hi-vis orange, For men, 2-layer Gore-Tex® Benbecula fabric, HiVis, Cold, Outdoor, Pockets: With pockets, Closure type: Press studs / snaps

Supplier: ORBIT

Long outdoor jacket made of 2-layer Gore-Tex® Benbecula fabric - windproof, waterproof and breathable. Can be combined with Corinthian or Trooper high-visibility vests and Crusader high-visibility fleece jacket (can be zipped in).

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High visibility rain jacket, Windsor 708Z

High visibility rain jacket, Windsor 708Z

Supplier: SIOEN

This waterproof and windproof jacket is made of Siopor® Extra fabric consisting of 100% PU laminated polyester fabric (cotton touch). The fabric is water repellent on the outside and moisture attracting on the inside. With fixed mesh lining in body and polyamide lining in sleeves.

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Trousers, Fristads® PR54-220, Design B, Royal Blue

Trousers, Fristads® PR54-220, Design B, Royal Blue

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

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96-well permeable support systems and plates, HTS Transwell®

96-well permeable support systems and plates, HTS Transwell®

Supplier: Corning

Permeable supports for HTS (high throughput screening) applications are excellent for ADMET screening, drug transport, and other assays.

    
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Removable needles

Removable needles

Supplier: HAMILTON BONADUZ

The benefit of a replaceable needle for the occasional bend or clog and the minimal dead volume of a cemented needle. The unique removable needle design installs the needle precisely at the zero line. The result is a zero dead volume connection that simplifies priming.

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T-shirts, cotton comfort, S172

T-shirts, cotton comfort, S172

Supplier: Portwest

This T-shirt uses comfortable, breathable cotton comfort fabric combined with HiVisTex tape for enhanced visibility.

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Masterflex® L/S® MasterSense® Fill/Finish Pump System with Masterflex Ultrapharm™ Pump Head, Avantor®

Masterflex® L/S® MasterSense® Fill/Finish Pump System with Masterflex Ultrapharm™ Pump Head, Avantor®

Supplier: Avantor Fluid Handling

A highly accurate benchtop pump system for dosing, dispensing, and fill/finish applications.

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VWR® pHenomenal® CO 3100 H Conductivity/TDS/°C Meter, Handheld

VWR® pHenomenal® CO 3100 H Conductivity/TDS/°C Meter, Handheld

Supplier: VWR Collection

This user friendly portable instrument with robust IP 67 rated housing provides high resolution and accuracy for precise measurements in field applications. Complete with waterproof USB output for connection to a computer. GLP compliant.

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VWR® Premium 150, Premium 90 HR, Automatic Colony Counters

VWR® Premium 150, Premium 90 HR, Automatic Colony Counters

Supplier: VWR Collection

Premium 150 and Premium 90 HR colony counters and zone measurements systems.

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VWR® PFAS Short Thread or Snap Ring Caps

VWR® PFAS Short Thread or Snap Ring Caps

Supplier: VWR Collection

PFAS PP short thread caps or PE snap ring caps, light green, with hole. White silicone/transparent polypropylene, for PFAS analysis.

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Chemical resistant overalls, Tyvek® 600 Plus, models CHA5a / CHA6

Chemical resistant overalls, Tyvek® 600 Plus, models CHA5a / CHA6

Supplier: DuPont

These Tyvek® overalls are made from flash spun, high density polyethylene, providing an ideal balance of protection, durability and comfort. Tyvek® is permeable to both air and water vapour, yet repels water-based liquids and aerosols. It offers an excellent barrier against fine particles and fibres (down to 1 micron in size).

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Anti-DDX11 Rabbit Polyclonal Antibody (Cy5.5®)

Supplier: Bioss

DNA helicase involved in cellular proliferation. Possesses DNA-dependent ATPase and helicase activities. This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding. The helicase activity is capable of displacing duplex regions up to 100 bp, which can be extended to 500 bp by RPA or the cohesion establishment factor, the Ctf18-RFC (replication factor C) complex activities. Stimulates the flap endonuclease activity of FEN1. Required for normal sister chromatid cohesion. Required for recruitement of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance. Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy. May function during either S, G2, or M phase of the cell cycle. Binds to both single- and double-stranded DNA.Tissue specificity: Highly expressed in spleen, B-cells, thymus, testis, ovary, small intestine, and pancreas. Very low expression seen in the brain. Expressed in dividing cells and/or cells undergoing high levels of recombination. No expression is seen in cells signaled to terminally differentiate. Expressed in keratinocyte growth factor-stimulated cells but not in serum, EGF and IL1-beta-treated keratinocytes.

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Centrifuges, benchtop, ventilated/refrigerated, 5702 / 5702 R / 5702 RH (IVD marked)

Centrifuges, benchtop, ventilated/refrigerated, 5702 / 5702 R / 5702 RH (IVD marked)

Supplier: EPPENDORF

The 5702 range of centrifuges is ideal for medical routine, clinical and biotechnology research.

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BRUTE® Vented Dustbins

BRUTE® Vented Dustbins

Supplier: Rubbermaid Commercial Products

Highly durable waste containers created with the toughest enviroments in mind.

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Industrial jacket, Fristads® PR54-420, design B, royal blue

Industrial jacket, Fristads® PR54-420, design B, royal blue

Supplier: FRISTADS KANSAS

Thanks to its durability and high degree of comfort, the PR54 jacket is perfectly suited to workshops and industrial and service enterprises. The material is made from 65% polyester and 35% cotton. The inside is brushed and as a result conveys a pleasantly comfortably cotton feeling. The outside is also resistant to the roughest demands and will not fade even after countless washes.

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Trousers, Fristads® PR54-220, Design B, dark grey

Trousers, Fristads® PR54-220, Design B, dark grey

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

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High visibility rain jacket with detachable softshell jacket, Powell 401A

High visibility rain jacket with detachable softshell jacket, Powell 401A

Supplier: SIOEN

This multifunctional, water- and wind-proof garment consists of a light rain jacket in a very breathable material and a smart softshell jacket with detachable sleeves. Made from highly breathable Siopor® Ultra fabric consisting of 100% polyester with 100% PU coating, with fixed mesh lining and knitted wind cuffs in the sleeves.

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Winter jacket, flame retardant, MULTISECURO

Winter jacket, flame retardant, MULTISECURO

Supplier: RENTEX

Lined jacket made from 55% modacrylic, 43% cotton and 2% Nega-Stat® with PTFE coating. The lining is made from 100% cotton with flame-resistant Proban® coating. Filling is made from 100% viscose FR.

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Urine collection tubes, vacuum, Vacutest®

Urine collection tubes, vacuum, Vacutest®

Supplier: KIMA SAS DI CHIARIN RENZO

Cylindical test tubes with round or conical bottom

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Industrial jacket, Fristads® PR54-420, design A, black

Industrial jacket, Fristads® PR54-420, design A, black

Supplier: FRISTADS KANSAS

Thanks to its durability and high degree of comfort, the PR54 jacket is perfectly suited to workshops and industrial and service enterprises. The material is made from 65% polyester and 35% cotton. The inside is brushed and as a result conveys a pleasantly comfortably cotton feeling. The outside is also resistant to the roughest demands and will not fade even after countless washes.

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HyperSep™ Retain™ PEP SPE columns

HyperSep™ Retain™ PEP SPE columns

Supplier: Thermo Fisher Scientific

HyperSep™ Retain™ PEP polymeric SPE material is a high purity, highly porous polystyrene DVB (divinyl benzene) material modified with urea functional groups to give balanced retention of polar and non polar analytes. HyperSep™ Retain™ PEP is ideal for a wide range of applications, such as drugs and metabolites in biological fluids, peptides in serum, plasma or biological fluids and environmental fluids.

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High visibility trousers, Essential Hi-Vis

High visibility trousers, Essential Hi-Vis

Supplier: FRISTADS KANSAS

These trousers made of 70% polyester and 30% cotton have four reflective stripes around the lower legs.

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Poloshirts, Ladies Polo Shirt, Poloshirts, 0455, XL, Cotton, Pink, For ladies, 90% pre-shrunk, ring-spun, combed cotton and 10% viscose, Weight: 180 g/m², Casual, General Purpose, Pockets: Without pockets, Closure type: Buttons

Poloshirts, Ladies Polo Shirt, Poloshirts, 0455, XL, Cotton, Pink, For ladies, 90% pre-shrunk, ring-spun, combed cotton and 10% viscose, Weight: 180 g/m², Casual, General Purpose, Pockets: Without pockets, Closure type: Buttons

Supplier: TRENKA

This exclusive fine piqué polo shirt is made from 100% ring-spun combed cotton. The gray model is made from 90% preshrunk ring-spun combed cotton and 10% viscose.

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Holster trousers, WX3

Holster trousers, WX3

Supplier: Portwest

Portwest WX3 contemporary workwear is designed to the highest standards and offer a solution for everyday activity and working environments. Constructed with cutting edge fabrics giving superior abrasion resistance and exceptional all-day comfort. The WX3 holster trousers are made from durable poly-cotton canvas fabric and includes triple stitched seams and stretch panelling providing excellent comfort and flexibility.

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Trousers, Trousers, Trousers, TrenkaTex®, 48 (men), Nomex®, Blue, For men, 94% Nomex® III, 5% ParaAramid and 1% metal, Weight: 260 g/m², Anti-static, Flame-retardant, Heat, Industrial, Fire protection, Pockets: With pockets, Closure type: Zip closure

Supplier: RENTEX

Chemical resistant, flame retardant trousers made from 94% Nomex® III, 5% Para-Aramid and 1% metal. The material is also permanently antistatic. Increased wearing comfort due to light fabric.

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Trousers, Fristads® PR54-220, Design B, Navy blue

Trousers, Fristads® PR54-220, Design B, Navy blue

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

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Trousers, Fristads® PR54-220, Design A, navy blue (long sizes)

Trousers, Fristads® PR54-220, Design A, navy blue (long sizes)

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

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Bib and braces, Overall, bib and brace, Bib and braces, TrenkaTex®, Canvas 310, 54 (men), Polyester/cotton, Blue, For men, 65% polyester and 35% cotton, Weight: 310 g/m², HiVis, General Purpose, Industrial, Pockets: With pockets, Closure type: Zip closure

Bib and braces, Overall, bib and brace, Bib and braces, TrenkaTex®, Canvas 310, 54 (men), Polyester/cotton, Blue, For men, 65% polyester and 35% cotton, Weight: 310 g/m², HiVis, General Purpose, Industrial, Pockets: With pockets, Closure type: Zip closure

Supplier: RENTEX

Bib and braces, Overall, bib and brace, Bib and braces, TrenkaTex®, Canvas 310, 54 (men), Polyester/cotton, Blue, For men, 65% polyester and 35% cotton, Weight: 310 g/m², HiVis, General Purpose, Industrial, Pockets: With pockets, Closure type: Zip closure

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