65668 Results for: "4-Bromobutyryl+chloride&pageNo=50&view=list"

Supplier: Amarell

Thermometer similar to IP Abel Water-Bath Celsius, solid stem, white backed, 32+88:0,5°C, capillary tube specially coated inside, w ith non-wetting blue special liquid, sdurable pigment, null

Supplier: Amarell

Thermometer similar to IP Abel Oil Cup Celsius, solid stem, white backed, 10+65:0,5°C, capillary tube specially coated inside, with non-wetting blue special liquid, durable pigment, null

Supplier: Corning

50µl Pre-Sterilized Hamilton CO-RE Style Clear Filter Tip. 96 Tips per Rack, 5 Racks/pack, 12 packs/case 1 * 5.760 items

Supplier: Amarell

Thermometer similar to BS 593, F75C/100, 24+78:0,2°C, solid stem, white backed, capillary tube specially coated inside, with non-we tting blue special liquid, 395mm long, 100mm immersion, durable pigment null

Supplier: Amarell

Thermometer similar to BS 1365, SB55C/total, 45+55:0,1°C, solid stem, white backed, capillary tube specially coated inside, with no n-wetting blue special liquid, 235mm long, total immersion, durable pigment, null

Supplier: ProSci Inc.

The Fas is also known as FAS receptor (FasR), apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6). is a death receptor on the surface of cells that leads to programmed cell death (apoptosis). It is one of two apoptosis pathways, the other being the mitochondrial pathway. FasR is located on chromosome 10 in humans and 19 in mice. Similar sequences related by evolution (orthologs) are found in most mammals. Fas forms the death-inducing signaling complex (DISC) upon ligand binding. Membrane-anchored Fas ligand trimer on the surface of an adjacent cell causes trimerization of Fas receptor. This event is also mimicked by binding of an agonistic Fas antibody, though some evidence suggests that the apoptotic signal induced by the antibody is unreliable in the study of Fas signaling. To this end, several clever ways of trimerizing the antibody for in vitro research have been employed.Upon ensuing death domain (DD) aggregation, the receptor complex is internalized via the cellular endosomal machinery. This allows the adaptor molecule FADD to bind the death domain of Fas through its own death domain. Recently, Fas has also been shown to promote tumor growth, since during tumor progression, it is frequently downregulated or cells are rendered apoptosis resistant. Cancer cells in general, regardless of their Fas apoptosis sensitivity, depend on constitutive activity of Fas. This is stimulated by cancer-produced Fas ligand for optimal growth.

Supplier: ProSci Inc.

tumour Necrosis Factor- alpha (TNF- alpha) is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells following stimulation by bacterial LPS. Cells expressing CD4 secrete TNF- alpha while cells that express CD8 secrete little or no TNF- alpha. Synthesis of TNF- alpha can be induced by many different stimuli including interferons, IL2, and GM-CSF. The clinical use of the potent anti-tumour activity of TNF- alpha has been limited by the proinflammatory side effects such as fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF- alpha mutants with low systemic toxicity has been of intense pharmacological interest. Human TNF- alpha that binds to murine TNF-R55 but not murine TNF-R7, exhibits retained anti-tumour activity and reduced systemic toxicity in mice compared with murine TNF- alpha, which binds to both murine TNF receptors. Based on these results, many TNF- alpha mutants that selectively bind to TNF-R55 have been designed. These mutants displayed cytotoxic activities on tumour cell lines in vitro and have exhibited lower systemic toxicity in vivo. Recombinant Human TNF- alpha High Active Mutant differs from the wild-type by amino acid subsitution of amino acids 1-7 with Arg8, Lys9, Arg10 and Phe157. This mutant form has been shown to have increased activity with less inflammatory side effects in vivo.

Supplier: STEMCELL Technologies

The B18R protein, which is encoded by the B18R open reading frame in the Western Reserve (WR) strain of vaccinia virus, is a type I interferon (IFN)-binding protein that is known to inhibit IFN antiviral response (Colamonici et al.). B18R protein has been shown to exhibit neutralizing activity to type I interferon family members (Meyers et al.) and to protect cells from the antiviral effects of interferon (Vancová et al.). It was recently shown that HIV-1–dependent induction of type I IFN activity and BAFF protein levels was abrogated by the soluble B18R protein, with no effect observed on the cell viability (Gomez et al.). B18R protein has been reported to aid in cellular reprogramming using RNA-mediated gene delivery (Warren et al.; Yoshioka N et al.).

Supplier: Amarell

Soil therm., British type, similar specification, right angle, -7+38:0,5°C, solid stem, white backed, red special liquid, round bulb with diameter 11,5-14,0mm, built-in length 75mm (MK2B), lower part 100mm, suitable for government verification 1 * 1 items

Supplier: Amarell

Metal ferrules, DIN 12787 mounted on Viscometer therm., Vogel-Ossag 1 * 1 items

Supplier: Amarell

Thermometer similar to S.T.P.T.C. T 17d, solid stem, white backed, 39,5+70,5:0,1°C, length 400mm, imm. 100mm, capillary tube specia lly coated inside, with non-wetting blue special liquid, durable pigment, null

Supplier: KAISER FOTOTECHNIK

Lichtleiter zur macrospot 1500, Typ: Lichtleiter, 2-armig 1 * 1 ST

Supplier: Thermo Fisher Scientific

PISTON 1 * 1 items

Supplier: Thies Clima

SCHREIBSTREIFEN 0-50C 0-100 31 TAGE 1 * 100 ST

Supplier: SELECTA

FIXED ROTOR 6 TUBES 50ML 1 * 1 items

Supplier: Amarell

Density hydrometer, 1,060-1,120:0,001g/cm , ref. temp. 20C, with therm., 350mm long, special liquid 1 * 1 items

Supplier: LP ITALIANA

BOTTLE LDPE WIDE NECK 50ML W/GASKET 1 * 160 items

Supplier: Amarell

Thermometer similar to BS 1900, SR6/51C, 33+51:0,05°C, length 480mm, total immersion, solid stem, white backed, capillary tube spec ially coated inside, with non-wetting blue special liquid, with ice point scale, null

Supplier: Merck

ALCONOX DETERGENT 1 * 1 items

Supplier: AccuStandard

3,3',4,4'-TETRABROMODIPHENYL 1 * 1 ml

Supplier: Sorenson Bioscience

MultiGuard 1000XT Barrier Tip, Natural, Racked 1 * 768 items

Supplier: Hospidex

MICROSYRINGE 50µL GAS ANALYSIS MS/GF INTERCHANGEABLE NEEDLE 1 * 1 items

Supplier: NEN LIFE SCIENCE

INDIVIDUAL CYANINE 5 TYRAMIDE REAGENT PA 1 * 1 ST

Supplier: VACUUBRAND

Package Fine vacuum control CVC3000 + VSP3000, KF DN 25 1 * 1 items

Supplier: Amarell

Density hydrometer, 1,200-1,400:0,002g/cm , ref. temp. 20C, with therm., 0+40:1C, 350mm long, special liquid 1 * 1 items

Supplier: Amarell

Thermometer, maxi T, digital, electronic, measuring range: -10:200/0.1C, piercing probe of stainless steel 125x3.5mm, switchable F , maximum/minimum function, hold-function, water-resistant. 1 * 1 items

Supplier: MACHEREY-NAGEL

Filter paper folded MN 715 1/4 50.0cm diameter, pack of 100. 1 * 100 items

Supplier: CAPITAL SAFETY

Protecta Shock Absorbing Lanyard 140 kg capacity, Rope Single Leg, adjustable length 1,5 - 2,0 m, screw gate carabiner, 17 mm openin g, 25 kN breaking strength, screw gate carabiner, 17 mm opening, 25 kN breaking strength 1 * 1 items

Supplier: witeg Labortechnik

Homogenizer HS-30E, 200-5000 rpm, analog internal controller, as a set Set includes : Unit : HS-30E Clamp : CL200 for stirrer and homogeniser Plate stand with rod : ST110 plate 20x35 cm, rod dia. 16x h800 mm NOTE: No tissue grinder included! 1 * 1 items

Supplier: witeg Labortechnik

FLASK,ROUND BOTTOM,50ML,3 NECKS,BOROSIICATE GLASS,CENTRE NECK ST19/26,TWO ANGLED SIDE NECKS 20° ST14/23 1 * 1 items