30614 Results for: "2-(Difluoromethoxy)iodobenzene&pageNo=20&view=list"

Supplier: BUCHI

Septa for 220 ml bottles (12) 1 * 12 items

Supplier: Sartorius Balances

The Cubis® II laboratory balances are modular, therefore they allow to choose between applications and configurations which suit the best to the needs. These balances can be configured at the level of display, draftshields, software applications and hardware functions.

Supplier: Cytiva

illustra™ ExoProStar™ 1-STEP Kit uses illustra™ Exonuclease I and Alkaline Phosphatase for optimal removal of unincorporated primers and nucleotides. illustra™ ExoProStar™ improves digestion efficiency with no degradation of the target PCR product. The sample remains completely intact and ready for immediate use in manual or automated processes.

Supplier: STEMCELL Technologies

Interferon-gamma (IFN-γ), also known as type II interferon, is produced by T and NK cells, and in smaller amounts by dendritic cells and macrophages. IFN-γ is controlled by cytokines such as IL-12 and IL-18 secreted in response to infection (Schroder et al.). IFN-γ binds to a receptor complex and initiates signal transduction via the JAK/STAT pathway; this culminates in the transcription and activation of many genes that control a diverse array of immunological functions (De Weerd and Nguyen; Krause et al.). IFN-γ stimulates the antimicrobial and anti-tumor activity of macrophages, NK cells, and neutrophils (Billiau and Matthys) by promoting the activation of microbial effector functions such as production of reactive oxygen species, NO intermediates, complement, etc. (Schroder et al.). IFN-γ enhances MHC class I and II expression in dendritic cells and mononuclear phagocytes, as well as the production of IL-12 by dendritic cells. In B cells, IFN-γ stimulates survival and growth in both mouse and human cells, and redirects B cells from proliferation towards differentiation. IFN-γ favors the development of Th1 vs Th2 cells and stimulates monocyte differentiation and function (Schroder et al.).

Supplier: TRESTON

Hook R1, L80 /20kg (5pcs),L80 /20kg (5pcs) 1 * 1 items

Supplier: GERING

DENSIMET W THERM 0,9-0,94 0,0002 20C 1 * 1 items

Supplier: OHAUS

Cover For 0.5mL/1.5mL/2.0mL Tube Blocks 1 * 1 items

Supplier: TRESTON

Storage system 100/50/200 light grey,Standard part 1 * 1 items

Supplier: GERING

SACCHARIMETER PLATO 14-21 0,1 20C 1 * 1 items

Supplier: MACHEREY-NAGEL

POLYGRAM CEL 300 DEAE, 5x20 cm 1 * 50 items

Supplier: TRESTON

Storage system 100/60/200 light grey,Standard part 1 * 1 items

Supplier: TRESTON

Storage system 100/40/200 light grey,Standard part 1 * 1 items

Supplier: GERING

HYDROMET W THERM 1,000-1,250 0,005 20C 1 * 1 items

Supplier: GERING

SACCHARIMETER 0-30 0.1 BALLING TH 0-35°C 1 * 1 items

Supplier: DWK Life Sciences

SEPTUM 18MM BUTYL PTFE VIAL 1 * 100 items

Supplier: DWK Life Sciences

SCREW CAP WITH PTFE GASKET 1 * 100 items

Supplier: Alpha Laboratories

PASTEUR PIPETTE MICRO, LARGE BULB, STER/ 1 * 200 items

Supplier: GERING

HYDROMETER BRIX 25-30 0,02 20C 1 * 1 items

Supplier: Air Liquide

CRYOTANK ARPEGE 70,2ML RACKS,LEVEL 1 * 1 item

Supplier: Biotium

MINI SUPER HT PAP PEN2 1 EA 1 * 1 Each

Supplier: TRESTON

Storage system 100/30/200 light grey,Standard part 1 * 1 items

Supplier: SARSTEDT

2ml Autoanalyser Sample Cups for Hitachi Analysers (Polystyrene) 38x17mm 1 * 5.000 items

Supplier: STEMCELL Technologies

Midkine is a member of a unique family of heparin-binding growth factors that are structurally different from other fibroblast growth factors (Muramatsu; Takada et al.). Midkine is a proinflammatory cytokine, promoting the migration of leukocytes, fibrinolysis, and acting as a chemotactic agent towards neutrophils (Muramatsu; Said et al.; Takada et al.). It also regulates growth, differentiation, and development during the midgestion stage of embryogenesis, and promotes angiogenesis (Muramatsu; Said et al.; Takada et al.). The protein structure consists of three antiparallel β-sheets and is highly conserved between species (Muramatsu; Takada et al.). While the exact signal pathway is not known, proposed pathways include promoting LRP, inhibiting Src kinase, activating paxillin and STAT1α, activating PI2 and MAP kinases, suppressing caspases, binding to α6β1-integrin and tetraspanin, activating FAK, phosphorylating STAT3, suppressing STAT5 phosphorylation, activating ALK, activating PI3 kinase and transcription of NFkB, binding to neuroglycan C or nucleolin, and binding to eIF3 (Muramatsu). In cultured cells, midkine influences growth and survival of neural precursor cells, synthesis of cytokines from endothelial and renal epithelial cells, and promotes synthesis of extracellular matrices from fibroblasts (Muramatsu; Takada et al.).

Supplier: witeg Labortechnik

TEST TUBES, BORO-SILICATE GLASS, ROUND BOTTOM, ST19/26, 150X20MM 1 * 1 items

Supplier: Air Liquide

ARPEGE 70 + 2ml racks + level + automatic filling 1 * 1 item

Supplier: Air Liquide

CRYOTANK ARPEGE 70,2ML RACKS 1 * 1 item

Supplier: B. Braun

ORIGINAL PERFUSOR-SYRINGE 20ML WITHOUT SUCTION NEEDLE 1 * 50 items

Supplier: MARIENFELD

COVER GLASS PRECISION Ø20MM 1.5H 2-PART 1 * 1.000 items

Supplier: STEMCELL Technologies

Vascular endothelial growth factor (VEGF) is a heparin-binding homodimeric glycoprotein involved in vasculogenesis and angiogenesis. VEGF binds to FLT1 (VEGFR-1) and KDR (VEGFR-2), and activates Raf/MEK/ERK and PI3K/AKT pathways (Ferrara et al.). VEGF exists in multiple isoforms that result from alternative splicing of VEGF mRNA in the terminal exon. Proximal splice-site selection in exon 8 results in pro-angiogenic VEGFxxx isoforms (xxx is the number of amino acids), whereas distal splice-site selection results in anti-angiogenic VEGFxxxb isoforms (Nowak et al.). VEGF plays an important role in neurogenesis both in vitro and in vivo (Storkebaum et al.). It has neurotrophic effects on neurons of the central nervous system, and it promotes growth and survival of dopaminergic neurons and astrocytes. VEGF also promotes growth and survival of vascular endothelial cells, monocyte chemotaxis, and colony formation by granulocyte-macrophage progenitor cells (Ferrara et al.). Various splice variants of VEGF exist, with different functions. For example, it has been shown that VEGF isoform VEGF-164(165) and not VEGF-120(121) induces inflammation, stimulates intracellular adhesion molecule (ICAM)-1 expression on endothelial cells, and induces chemotaxis of monocytes (Usui et al.).

Supplier: Air Liquide

CRYOTANK ARPEGE 70,2ML RACKS,TEMP,LEVEL 1 * 1 item