Monocyte chemotactic protein-1 (MCP-1), also known as CCL2, is a member of the CC family of chemokines. The protein is primarily induced by platelet-derived growth factor (PDGF) gene (Cochran et al.). The biological effects of MCP-1 are mediated via the specific G-protein-coupled receptor CCR2 which in turn activates signal transduction pathways leading to monocyte transmigration (Sozzani et al.). Migration of monocytes from the bloodstream across the vascular endothelium is required for routine immunological surveillance of tissues, as well as other immunomodulatory effects. MCP-1 is produced by a variety of cell types, including fibroblasts and endothelial, epithelial, smooth muscle, mesangial, astrocytic, monocytic, and microglial cells, which are important for antiviral responses in the peripheral circulations and in tissues (Cushing et al.; Deshmane et al.). MCP-1 plays a role in physiological processes such as neurogenesis, neuroprotection, and neurotransmission and has important implications in neurological disorders such as multiple sclerosis and Alzheimer’s disease, in which it is produced during neuroinflammation at the sites of lesions (Conductier et al.).

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16 COMPONENTS MIX 1 * 5 Ampoul

Supplier: CUSTOM MADE CHEMICALS LAB

16 COMPONENTS MIX 1 * 5 Ampoul

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HYDROMET 0,01-0,02 20C 300MM 1 * 1 items

Supplier: GERING

HYDROMET 0,01-0,02 20C 300MM 1 * 1 items

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Heating thermostats, Proline

Supplier: LAUDA

The Proline Edition X range of heating thermostats feature a wide temperature range, high cooling and heating power and a multi level pump. The self-explanatory menu-guided remote control Command is particularly convenient for operating the units at distances as far as 50 meters away. Thanks to the large display, the user can keep an eye on all the important parameters. There is a graphical display of measured values, large choice of interfaces (e.g. Ether- CAT, Ethernet, RS232/RS485, analogue module, Profibus, contact modules). Data collection together with documentation and control is easy using the Wintherm Plus software. Units are ideal for temperature control of chemical reactors, distillation plants and glass condensers, crystallisation, thermostating measurement setups in process technology, chemical probes, calibration of sensors and testing electronic components.

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Septa for 220 ml bottles (12) 1 * 12 items

Supplier: BUCHI

Septa for 220 ml bottles (12) 1 * 12 items

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HYDROMETER BAUME 40-50 0,1 20C 1 * 1 items

Supplier: GERING

HYDROMETER BAUME 40-50 0,1 20C 1 * 1 items

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SAMPLE VESSEL 20ML VZ 5368 1 * 100 items

Supplier: SI Analytics

SAMPLE VESSEL 20ML VZ 5368 1 * 100 items

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HemaSep™ Blood Collection Cards

Supplier: Ahlstrom-Munksjö

HemaSep™ is a rapid, easy to use and cost-effective device to achieve high yield and purity of plasma/serum from whole blood.

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illustra™ NICK™ columns

Supplier: Cytiva

NICK™ columns were originally designed for purification of nick-translated DNA fragments but are also suitable for separation of any labelled probe from unincorporated labelled nucleotides.