10287 Results for: "1,3-Benzodioxole&pageNo=19"

Supplier: AAT Bioquest

Covidyte™ TF670 is a peptide substrate containing 14 amino acid sequence (KTSAVLQSGFRKME) that can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide Quencher™ 5 (TQ5) as a quencher and Tide Fluor™ 5 (TF5) as a fluorescent donor on the N-and C-terminals respectively where the fluorescence of TF5 is effectively quenched by TQ5 when the peptide is intact. When the peptide is hydrolysed by coronavirus proteases, the TF5 fragment generates significantly enhanced fluorescence since its fluorescence is no longer quenched by TQ5. The activity of coronavirus proteases can be effectively monitored by the fluorescence intensity of TF5. Covidyte™ TF670 is a robust high throughput screening tool for searching inhibitors of coronavirus proteases. TQ5-TF5 pair has been proven to an extremely effective FRET pair for developing FRET protease substrates. Comparing to the commonly used EDANS substrates (such as Covidyte™ EN450), the TF670 substrate has much stronger and longer fluorescence that is less interfered by coloured compounds that often cause false positive hits.

Supplier: FRISTADS KANSAS

These coats are made of XR50 fabric consisting of 97% polyester and 3% conductive fibre. The fabric is ideal for sterile environments.

Supplier: Portwest

The comfortable B300 Roma sweatshirt is ideal for work wear or casual weekend wear. Made of 65% polyester and 35% cotton.

Supplier: HORIBA

These waterproof meters can measure and display up to 11 parameters simultaneously with one single probe. Thanks to their rugged design and their field replaceable sensors they are ideal for outdoor use, for example, when testing ground or surface water. Their compact size and the hand strap enable one-handed operation.

Supplier: ALSICO

Comfortable multirisk trousers in inherent flame retardant fabric.

Supplier: BIOTIX

xTIP4™ is the only Rainin® LTS® compatible tip engineered with StarStop, a patented positive stop feature. This feature minimizes ejection force and reduces the risk of repetitive stress injuries (RSI).

Supplier: Oxford Nanopore Technologies

An expansion kit containing all the required reagents and primers to generate reverse-transcribed and PCR-amplified material from SARS-CoV-2 RNA samples.

Supplier: Hospidex

Sharpsafe®, historic pioneer in protecting against the risk of sharps injuries and sustainability in medical waste packaging management, presents the recycled 5th generation needle containers.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: LABCONCO

FreeZone® bench top freeze dryers are designed for lyophilising light to moderate sample loads. The compact design is ideal for laboratories with limited floor space.

Supplier: ERLAB CAPTAIRE

Ceiling mounted, laboratory grade filtration unit.
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Supplier: Bohlender

b.safe caps together with fittings, tubing and an air valve form a perfect unit for solvent extraction from laboratory flasks.

Supplier: MIELE

G 7896 DOS cabinet: for 1 to 4 DOS modules with containers.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Brady

Mark cables and wires with the B-427 self-laminating vinyl label material, designed with a clear self-laminating protective layer. Print almost anywhere with a durable Brady portable label printer.

Supplier: Cole Parmer

Motor Bearing Housing Assy 1 * 1 items

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

Supplier: ProSci Inc.

COLON TISSUE LYSATE (NORMAL) 1 * 0,1 mg

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

Supplier: OHAUS

Ideal for laboratory and industrial applications, the durable Scout® STX series features an easy to navigate colour touchscreen display and a slim design which allows stackable storage with optional storage cover.

Supplier: FRISTADS KANSAS

Dirt, oil and water repellent trousers with inherent flame protection adapted for ATEX environments with no metal details. Manufactured from 45% modacrylic, 35% cotton, 18% polyamide and 2% anti-static fibre. Approved for industrial laundry.

Supplier: FRISTADS KANSAS

These overalls consist of different fabric combinations. The fluorescent material is water repellent and manufactured from 80% polyester and 20% cotton. The other parts are made of 65% polyester and 35% cotton with a soft nap on reverse. The reinforcement is made from 100 % polyamide.

Supplier: SIOEN

Waterproof jacket made of Siopor® Ultra: 100 % polyester fabric with 100% PU coating and taped seams. The detachable bodywarmer with fixed quilted lining features detachable sleeves, several pockets and knitted windcuffs at the end of the sleeves.

Supplier: FRISTADS KANSAS

Industrial overall made of 65% polyester and 35% cotton, with soft nap on reverse side. The black overall is available with several different accent colours. The accent colour can be found on the top of the collar, on the inside front flap, on the pocket edges and and as a stripe on front and back.

Supplier: Portwest

Standard V-necked coats, made of Fortis Plus fabric consisting of 65% polyester and 35% cotton.

Supplier: HAMILTON ROBOTICS

Hamilton CO-RE tips were designed for MICROLAB pipetting workstations in order to solve the problem of sealing and alignment plagued by press-fit tip attachment techniques. Each CO-RE disposable tip has a circular groove inside the attachment orifice. An o-ring on the pipetting channel is expanded to fit this groove precisely providing an air-tight seal and straight alignment between tip and pipetting channel.