10287 Results for: "1,3-Benzodioxole&pageNo=19"

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Oxford Nanopore Technologies

An expansion kit containing all the required reagents and primers to generate reverse-transcribed and PCR-amplified material from SARS-CoV-2 RNA samples.

Supplier: Hospidex

Sharpsafe®, historic pioneer in protecting against the risk of sharps injuries and sustainability in medical waste packaging management, presents the recycled 5th generation needle containers.

Supplier: TRENKA

Wind- and waterproof, breathable high-visibility winter parka made from light Airtech® material (100% polyester) with removable quilted polyester lining. Approved for industrial washing at 60 °C.

Supplier: EPPENDORF

Versatile, ergonomic pipette with innovative design, meeting the highest needs in precision and accuracy.

Supplier: Portwest

This traditional t-shirt made of 50% polyester and 50% cotton offers optimum warmth at all times.

Supplier: Corning

PS. Designed to reduce well-to-well crosstalk during fluorescent and luminescent assays.

Supplier: RENTEX

Bib and braces, Overall, bib and brace, Bib and braces, TrenkaTex®, Comfort Stretch 285, 48 (men), Polyester/cotton, Beige, For men, 60% polyester, 35% cotton and 5% DOW XLA, Weight: 285 g/m², General Purpose, Industrial, Pockets: With pockets

Supplier: Portwest

This jacket is made of 300D Oxford weave polyester with a stain resistant finish and PU coating. Completely padded and lined, the jacket offers great freedom of movement.

Supplier: AAT Bioquest

Covidyte™ TF670 is a peptide substrate containing 14 amino acid sequence (KTSAVLQSGFRKME) that can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide Quencher™ 5 (TQ5) as a quencher and Tide Fluor™ 5 (TF5) as a fluorescent donor on the N-and C-terminals respectively where the fluorescence of TF5 is effectively quenched by TQ5 when the peptide is intact. When the peptide is hydrolysed by coronavirus proteases, the TF5 fragment generates significantly enhanced fluorescence since its fluorescence is no longer quenched by TQ5. The activity of coronavirus proteases can be effectively monitored by the fluorescence intensity of TF5. Covidyte™ TF670 is a robust high throughput screening tool for searching inhibitors of coronavirus proteases. TQ5-TF5 pair has been proven to an extremely effective FRET pair for developing FRET protease substrates. Comparing to the commonly used EDANS substrates (such as Covidyte™ EN450), the TF670 substrate has much stronger and longer fluorescence that is less interfered by coloured compounds that often cause false positive hits.

Supplier: FRISTADS KANSAS

These coats are made of XR50 fabric consisting of 97% polyester and 3% conductive fibre. The fabric is ideal for sterile environments.

Supplier: Portwest

The comfortable B300 Roma sweatshirt is ideal for work wear or casual weekend wear. Made of 65% polyester and 35% cotton.

Supplier: HORIBA

These waterproof meters can measure and display up to 11 parameters simultaneously with one single probe. Thanks to their rugged design and their field replaceable sensors they are ideal for outdoor use, for example, when testing ground or surface water. Their compact size and the hand strap enable one-handed operation.

Supplier: Avantor

Avantor® ACE® UltraCore SuperPhenylHexyl solid-core (core-shell) particle columns are ideal for demanding MS work offering improved MS signal intensity and maximum MS response. These stainless steel columns combine high efficiency separations with low column back pressure. The Encapsulated Bonding Technology (EBT™) greatly increases the ligand coverage of the silica surface and effectively eliminates the effect of unbonded silanol groups on separations. This higher ligand coverage results in improved inertness, chromatographic performance and stability.

Supplier: GA

Cryogenic direct thermal labels intended for labeling already frozen surfaces and containers under deep-freeze conditions, as low as (–80 °C).

Supplier: Portwest

Breathable jacket made of 300 Denier polyester yarn which features superior abrasion and tear resistance. The PU coating on the inside makes the fabric durable and waterproof. The water- and stain-repellent coating on the outside helps to keep the garment clean. With nylon lining.

Supplier: ProSci Inc.

FAM19A3 is a member of the TAFA family which is composed of five highly homologous small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells.This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells.

Supplier: RENTEX

Lab coats, Industrial coat, Lab coats, TrenkaTex®, 48 (men), Polyester/cotton, Blue, For men, 65% polyester and 35% cotton, with Sanfor®, Weight: 245 g/m², General Purpose, Pockets: With pockets, Closure type: Press studs / snaps

Supplier: Bohlender

b.safe caps together with fittings, tubing and an air valve form a perfect unit for solvent extraction from laboratory flasks.

Supplier: FRISTADS KANSAS

Thanks to their durability and comfort, these trousers are perfectly suitable for use in garages as well as in industrial and service companies. The material is made of 65% polyester and 35% cotton. The inside is brushed and provides a comfortable cotton feel. The outside is very hardwearing and does not bleach, even after countless washes.

Supplier: Portwest

These overalls made of Portwest Texo fabric (60% cotton, 40% polyester), provide complete lower body and leg protection. The cotton ensures the trousers wash well at 60 °C while the polyester gives a ruggedness essential for daily use.

Supplier: FRISTADS KANSAS

These trousers are manufactured from the hardwearing FLAM fabric, made from a flame retardant 75/25 cotton/polyester blend. The trousers provide protection against open flames as well as against electrical arcs.

Supplier: HAIX SCHUHE

The safety shoes are especially designed for road maintenance and construction site workers who place the highest demands on their work shoes. The shoe is made of extra thick waterproof bull leather of the highest quality, with a thickness of at least 2,0 mm. This leather strength makes HAIX safety shoes particularly robust. The work shoes ensure the all-round feet protection needed for working on road maintenance or construction sites. The composite protective cap made of ultralight, fibre-reinforced plastic protects the toes from injury by, for example, falling objects. The shape of the toe cap leaves enough space for your feet, ensuring not only safety but also comfort at work.

Supplier: EPPENDORF

This reliable centrifuge for medium to high-throughput applications combines extraordinary versatility and capacity for both tubes and plates with an extraordinary compact footprint. Bucket adapters and adapter modules can be stacked until the required tube height is attained and then lowered onto the holders in the rectangular buckets. The stable plastic adapters are robustly constructed and can be easily cleaned, even autoclaved in their entirety in the event of contamination with biologically active sample material.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Bioss

The adenovirus E1B protein is a viral homolog of the Bcl-2 family of proteins that are involved in regulating cell death. A family of interacting proteins, which are designated Nip or Bnip and include BNIP-1, BNIP-2, BNIP-3 and Nix, associate with both the E1B protein and Bcl-2 proteins to mediate apoptotic signaling. BNIP-1 contains a hydrophobic transmembrane domain, which enables its localization to the nuclear envelope, endoplasmic recticulum and mitochondria. BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins. BNIP-3 preferentially binds to Bcl-xL and induces apoptosis by suppressing the anti-apoptosis activity of Bcl-xL.

Supplier: Brady

Mark cables and wires with the B-427 self-laminating vinyl label material, designed with a clear self-laminating protective layer. Print almost anywhere with a durable Brady portable label printer.