7-Ethyl-10-hydroxycamptothecin ≥98%

50 mg

Catalog # CAYM15632-50

Toxic

Health

Supplier: Cayman Chemical

7-Ethyl-10-hydroxycamptothecin ≥98%

Catalog # CAYM15632-50

Supplier: Cayman Chemical

CAS Number: 86639-52-3

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Specifications

CAS Number: 86639-52-3

Price

501,00 €

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Product Details & Documents

SN-38 is the active metabolite of irinotecan, a derivative of the alkaloid camptothecin and acts as a potent inhibitor of DNA topoisomerase I. SN-38 is a more potent topopisomerase I inhibitor and more cytotoxic to HT-29 colon cancer cells (IC₅₀ = 8.8 nM) compared to irinotecan (IC₅₀ >100 nM).

SN-38 is in a form of crystalline solid
λ_max at 224, 267, 331, 368, 383 nm

Synonyms: 10-hydroxy-7-ethylcamptothecin, (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 7-Ethyl-10-hydroxy-20(S)-Camptothecin, SN-38, NK 012

CAS Number:86639-52-3
Formula:C₂₂H₂₀N₂O₅
MDL Number:MFCD00871873
Molecular Weight:392.40 g/mol
Storage Temperature:Freezer
UN:2811
ADR:6.1,III

Specifications

Pk:
50 mg