Recombinant protein A agarose, Pierce™

Pierce™ Recombinant Protein A agarose is a beaded agarose resin to which a genetically engineered form of Protein A has been immobilised for use in IgG purification applications where the native ligand has undesirable effects.

• Immobilised Protein A is ideal for polyclonal IgG purification from human and rabbit
• Support is crosslinked 6% beaded agarose (CL-6B), the most popular resin for protein affinity purification methods
• Standard capacity beads with a normal load of immobilized Protein A, providing a binding capacity of 15 to 17 mg human IgG/ml resin

Although some non essential regions have been removed, recombinant is similar to native Protein A in overall size and IgG-binding domains. The protein has four high affinity binding sites capable of specifically binding to the Fc region of immunoglobulin molecules from several species.