DIVTECH Small Molecule Delivery Nanoparticles

DIVERSA’s Small molecule delivery nanoparticles simplify the challenge of formulating poorly water soluble compounds. With their high loading efficiency and proven stability in biological environments, they enable researchers to explore drug activity in both simple cell models and complex in vivo systems. Designed for fast, reproducible results, the kit provides flexibility for discovery projects and translational research. A fluorescent option is also available to streamline visualisation and biodistribution studies.

• Easy-to-use and ready-to-load nanoparticle formulation

  High loading capacity for hydrophobic and amphiphilic compounds

  Suitable for in vitro and in vivo applications

  Compatible with 2D and 3D cell culture models, including immortalise cells, primary cells and organoids

  Fluorescent version available for tracking

  Non-toxic and biodegradable components

  Stable in biological media

  No specialised equipment required for preparation

Poor water solubility remains a major obstacle in the development of many promising drug candidates, particularly hydrophobic small molecules. While such compounds can dissolve in solvents like DMSO, their limited solubility in biological media restricts their applicability in preclinical models. DIVERSA’s Small molecule delivery nanoparticles address this challenge by encapsulating small molecules into biocompatible, stable carriers that remain functional in serum-containing environments.

The platform provides high loading efficiency for hydrophobic and amphiphilic drugs, enabling researchers to assess pharmacological effects across 2D, 3D, and animal models. The kit is designed for straightforward use without specialised equipment, accelerating experimental workflows. Optional fluorescent versions allow monitoring of nanoparticle distribution, uptake, and release using standard detection methods such as microscopy, flow cytometry, or plate readers. By combining versatility with reproducibility, DIV010 empowers researchers to unlock the therapeutic potential of otherwise poorly soluble molecules.

Delivery information: The kit contains four vials with the lipid mix for formulation. Each kit is provided with 4X DIVTECH empty vial for formulation preparation. Includes eight pipette tips for 1 ml pipette to support accurate handling. Lot number and storage conditions indicated on every vial and box.

Caution: Products are intended for research use only (RUO).