AC-55541 ≥98% protease-activated receptor 2 (PAR2) agonist

Potent, selective protease-activated receptor 2 (PAR2) agonist that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. Stimulates cell proliferation, PI hydrolysis and Ca²⁺ mobilization in vitro(pEC50 values are 6,7, 5,9 and 6,6 respectively) and exhibits pronociceptive activity in vivo.

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