- Pack type:Vial
- Pk:1 KIT
- Conjugation:Unconjugated
- Protein function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Seq:0075
- Environmentally Preferable:
- Storage conditions:At or below −20 °C
- Biological activity:Bioactivity: No biological activity data is available at this time
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:N
- Endotoxin level:Low
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT
Cytokines for polarizing human T cells into Th9 cells. Th9 cells are a unique subset of T helper cells that produce IL-9. An important function of IL-9 producing T cells is fighting inflammation and helminth infections. Th9 cells can be generated from naive CD4+ T cells in culture by culturing them in the presence of IL-4 and TGF-β 1. It also appears that IFNγ and IL-27 can inhibit the generation of Th9 cells.
- High quality
- Low endotoxin
- Affordable
Th17 cells are characterized by their ability to produce IL-17, IL-22 and IL-21. Th17 cells can be cultured from naive CD4+ T cells by culturing them in the presence of anti-CD3 and anti-CD28 stimulation with recombinant IL-6 and recombinant TGF-β 1. In some cases neutralizing antibodies against IL-12, IL-4 and IFNγ are used along with recombinat cytokines IL-1 β, IL-21 and/or IL-23.