cGMP, human T cell activation and expansion reagent.

Achieve robust activation and expansion of human T cells for use in clinical applications–without the use of magnetic beads, feeder cells, or antigens. This product’s gentle activation stimulus ensures a high viability of activated T cells, which can be further expanded in ImmunoCult™-XF - a high-performance T cell expansion medium manufactured under relevant cGMP regulations and guidelines. ImmunoCult™ Human CD3/CD28 T Cell Activator consists of soluble antibody complexes that bind to and cross-link CD3 and CD28 cell surface ligands, thereby providing the required primary and co-stimulatory signals for T cell culture and activation.

ImmunoCult™ Human CD3/CD28 T Cell Activator is designed for cell therapy clinical research applications by qualifying it for use as an ancillary material (AM) following the framework outlined in USP and/or PH. EUR. 5.2.12. STEMCELL can work with you to qualify this reagent as an AM under an approved Investigational New Drug (IND) application, Biological Licensing Application (BLA), or Clinical Trial Application (CTA).