Specifications
- Antibody type:Primary
- Antigen name:Hepcidin 25
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Epitope:60-84/84
- Form:Liquid
- Gene ID:57817
- Antigen synonyms:Hamp|HFE2B|PLTR|Hepcidin|Hepc20|Liver expressed antimicrobial peptide|Liver-expressed antimicrobial peptide 1|Hepcidin 20|Hepcidin-20|LEAP 1|Hepcidin 25|HEPCIDIN|Putative liver tumor regressor|LEAP1|Hepcidin antimicrobial peptide|HFE2|HEPC_HUMAN|LEAP-1|Hepcidin25|Hepc25|HEPC
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:2-Sep kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Hepcidin 25
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.
Type: Primary
Antigen: Hepcidin 25
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 60-84/84
Host: Rabbit
Isotype: IgG
Reactivity: Human