Anti-GZMA/Granzyme A Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-2578R-A750
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:GZMA/Granzyme A
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western blot:Yes
- Epitope:101-200/262
- Form:Liquid
- Gene ID:3001
- Antigen synonyms:GZMA|Fragmentin-1|HF|Granzyme-1|CTL tryptase|Cytotoxic T-lymphocyte proteinase 1|HFSP|H factor|Granzyme A|Hanukkah factor|CTLA3
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:26 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Granzyme A
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
Type: Primary
Antigen: GZMA/Granzyme A
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 101-200/262
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse