Order Entry
Export
ContactUsLinkComponent
Anti-GZMA/Granzyme A Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-GZMA/Granzyme A Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-2578R-A750
Supplier:  Bioss
Anti-GZMA/Granzyme A Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-2578R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    GZMA/Granzyme A
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Mouse
  • Western blot:
    Yes
  • Epitope:
    101-200/262
  • Form:
    Liquid
  • Gene ID:
    3001
  • Antigen synonyms:
    GZMA|Fragmentin-1|HF|Granzyme-1|CTL tryptase|Cytotoxic T-lymphocyte proteinase 1|HFSP|H factor|Granzyme A|Hanukkah factor|CTLA3
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    26 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human Granzyme A
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.

Type: Primary
Antigen: GZMA/Granzyme A
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 101-200/262
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse