Anti-OVCA1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-5714R-A750
Supplier: Bioss
Specifications
- Antibody type:Primary
- Antigen name:OVCA1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Epitope:251-350/443
- Form:Liquid
- Gene ID:1801
- Antigen synonyms:DPH1_HUMAN|DPH1|Candidate tumor suppressor in ovarian cancer 1|DPH2L1|Diphthamide biosynthesis protein 2 like|Ovarian cancer associated gene 1 protein|Diptheria toxin resistance protein required for diphthamide biosynthesis like 1|DPH like 1|Diphthamide biosynthesis protein 1|Diphthamide biosynthesis protein 2 homolog like 1|DPH1 homolog S. cerevisiae|DPH2 like 1|DPH1 homolog|Diptheria toxin resistance protein required for diphthamide biosynthesis Saccharomyces like 1 |DPH like 1 S. cerevisiae|Ovarian tumor suppressor candidate 1|HsDph1|Ovarian cancer associated gene 1|DPH2L
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:49 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human OVCA1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
OVCA1 is required for the first step in the synthesis of diphthamide, a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. OVCA1 is one of several enzymes involved in synthesis of diphthamide in EEF2.
Type: Primary
Antigen: OVCA1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 251-350/443
Host: Rabbit
Isotype: IgG
Reactivity: Human