Anti-Complement component C9b Rabbit Polyclonal Antibody (FITC)
Product Details & Documents
C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerisation of 12-18 C9 molecules. These polymerised C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
Type: Primary
Antigen: Complement component C9b
Clonality: Polyclonal
Clone:
Conjugation: FITC
Public Immunogen Range: 251-350/559
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse
Documents
bs-15307R-FITC
Datasheet
Specifications
- Pack type:Vial
- Western blot:Yes
- Clonality:Polyclonal
- Flow cytometry:Yes
- Modification:Unmodified
- Purification:Purified by Protein A
- Antibody type:Primary
- Epitope:251-350/559
- Form:Liquid
- Isotype:IgG
- Storage temperature:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Host:Rabbit
- Concentration:1 µg/µl
- Molecular weight:32/61 kDa
- Shipping temperature:4 °C
- Antigen name:Complement component C9b
- Cat. No.:BOSSBS-15307R-FITC
- Reactivity:Human|Mouse
- Gene ID:735
- Antigen synonyms:Complement component C9|Complementcomponent C9b|CO9_HUMAN
- Immunogen:KLH conjugated synthetic peptide derived from human Complement component C9b
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol