Derivatization Kit for the sensitive LC-MS analysis of oxysterols.

• Oxidation and derivatization kit for mass spec analysis of oxysterols
• Includes labelled and unlabelled derivatizing reagents that allow for a variety of sample workflows
• Can be used for quantitation or untargeted profiling methods

Cayman's Oxysterol Derivatization MaxSpec® Kit is designed for the sensitive detection and relative quantitation of oxysterols in biological samples. This is achieved through enzyme-assisted derivatization utilising d₀/d₅ labelled Girard’s P reagent to give GP hydrazones. The instrumental response of the derivatized oxysterols is significantly improved due to the presence of a positively charged quaternary nitrogen group in the labelled and unlabelled GP hydrazones. Included in this kit are the essential reagents to derivatize oxysterols in mixtures for sensitive and comparative LC-MS analysis.