Human Recombinant IL-10 (from E. coli)
Supplier: Shenandoah Biotechnology
About this item
Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFN-ɣ), tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. Human IL-10 can act on murine cells, while murine IL-10 is not active on human cells.
- High quality
- Low endotoxin
- Affordable
: This product is for research use only and is not for use in humans.
4 Options Available Below
Product Details & Documents
Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFN-ɣ), tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells. Human IL-10 can act on murine cells, while murine IL-10 is not active on human cells.
- High quality
- Low endotoxin
- Affordable
: This product is for research use only and is not for use in humans.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT100-83AF-10UG
- SHBT100-83AF-100UG
- SHBT100-83AF-500UG
- SHBT100-83AF-1MG
- Protein/peptide name:
- IL-10 (AF)
- IL-10 (AF)
- IL-10 (AF)
- IL-10 (AF)
- Protein synonyms:
- B-TCGF|TGIF|CSIF
- B-TCGF|TGIF|CSIF
- B-TCGF|TGIF|CSIF
- B-TCGF|TGIF|CSIF
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Species:
- Human
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- P22301
- P22301
- P22301
- P22301
- Sequence:
- MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
- MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
- MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
- MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
- Protease-free:
- N
- N
- N
- N
- Animal-free:
- Y
- Y
- Y
- Y
- Nuclease-free:
- N
- N
- N
- N
- Carrier-free:
- Y
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- N
- Endotoxin level:
- Low
- Low
- Low
- Low
- Endotoxin content:
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Biological activity:
- Bioactivity Assay: MC/9 cell Proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
- Bioactivity Assay: MC/9 cell Proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
- Bioactivity Assay: MC/9 cell Proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
- Bioactivity Assay: MC/9 cell Proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mg
- Purity:
- ≥97%
- ≥97%
- ≥97%
- ≥97%
- Grade:
- RUO
- RUO
- RUO
- RUO
- Formulation:
- 10 mM Sodium phosphate, pH 7,5
- 10 mM Sodium phosphate, pH 7,5
- 10 mM Sodium phosphate, pH 7,5
- 10 mM Sodium phosphate, pH 7,5
- Molecular weight:
- 18,8 kDa
- 18,8 kDa
- 18,8 kDa
- 18,8 kDa
- Reconstitution instructions:
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Storage conditions:
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- Shipping temperature:
- RT
- RT
- RT
- RT
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- Pack typePkAvailabilityPrice
- Specifications:
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Specifications
Cat. No.SHBT100-83AF-10UGProtein/peptide nameIL-10 (AF)Protein synonymsB-TCGF|TGIF|CSIFProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP22301SequenceMSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR NProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity Assay: MC/9 cell Proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mgPurity≥97%GradeRUOFormulation10 mM Sodium phosphate, pH 7,5Molecular weight18,8 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-83AF-100UGProtein/peptide nameIL-10 (AF)Protein synonymsB-TCGF|TGIF|CSIFProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP22301SequenceMSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR NProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity Assay: MC/9 cell Proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mgPurity≥97%GradeRUOFormulation10 mM Sodium phosphate, pH 7,5Molecular weight18,8 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-83AF-500UGProtein/peptide nameIL-10 (AF)Protein synonymsB-TCGF|TGIF|CSIFProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP22301SequenceMSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR NProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity Assay: MC/9 cell Proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mgPurity≥97%GradeRUOFormulation10 mM Sodium phosphate, pH 7,5Molecular weight18,8 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-83AF-1MGProtein/peptide nameIL-10 (AF)Protein synonymsB-TCGF|TGIF|CSIFProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDP22301SequenceMSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR NProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity Assay: MC/9 cell Proliferation, ED₅₀ ≤5 ng/ml, Bioactivity ≥2,0×10⁵ units/mgPurity≥97%GradeRUOFormulation10 mM Sodium phosphate, pH 7,5Molecular weight18,8 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay