Mouse Recombinant TNF-A (from E. coli)
About this item
Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.
- High quality
- Low endotoxin
- Affordable
Caution: This product is for research use only and is not for use in humans.
5 Options Available Below
Product Details & Documents
Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.
- High quality
- Low endotoxin
- Affordable
Caution: This product is for research use only and is not for use in humans.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT200-31AF-5UG
- SHBT200-31AF-20UG
- SHBT200-31AF-100UG
- SHBT200-31AF-500UG
- SHBT200-31AF-1MG
- Protein/peptide name:
- TNF-A (AF)
- TNF-A (AF)
- TNF-A (AF)
- TNF-A (AF)
- TNF-A (AF)
- Protein synonyms:
- Cytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|Cachectin
- Cytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|Cachectin
- Cytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|Cachectin
- Cytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|Cachectin
- Cytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|Cachectin
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Species:
- Mouse
- Mouse
- Mouse
- Mouse
- Mouse
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- P06804
- P06804
- P06804
- P06804
- P06804
- Sequence:
- MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
- MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
- MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
- MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
- MLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIAL
- Protease-free:
- N
- N
- N
- N
- N
- Animal-free:
- Y
- Y
- Y
- Y
- Y
- Nuclease-free:
- N
- N
- N
- N
- N
- Carrier-free:
- Y
- Y
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- N
- N
- Endotoxin level:
- Low
- Low
- Low
- Low
- Low
- Endotoxin content:
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Biological activity:
- Bioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mg
- Bioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mg
- Bioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mg
- Bioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mg
- Bioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Grade:
- RUO
- RUO
- RUO
- RUO
- RUO
- Formulation:
- 10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5
- Molecular weight:
- 17,4 kDa
- 17,4 kDa
- 17,4 kDa
- 17,4 kDa
- 17,4 kDa
- Reconstitution instructions:
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Storage conditions:
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- Shipping temperature:
- RT
- RT
- RT
- RT
- RT
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- Pack typePkAvailabilityPrice
- Specifications:
More
Specifications
Cat. No.SHBT200-31AF-5UGProtein/peptide nameTNF-A (AF)Protein synonymsCytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|CachectinProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP06804SequenceMLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIALProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5Molecular weight17,4 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-31AF-20UGProtein/peptide nameTNF-A (AF)Protein synonymsCytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|CachectinProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP06804SequenceMLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIALProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5Molecular weight17,4 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-31AF-100UGProtein/peptide nameTNF-A (AF)Protein synonymsCytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|CachectinProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP06804SequenceMLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIALProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5Molecular weight17,4 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-31AF-500UGProtein/peptide nameTNF-A (AF)Protein synonymsCytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|CachectinProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP06804SequenceMLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIALProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5Molecular weight17,4 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-31AF-1MGProtein/peptide nameTNF-A (AF)Protein synonymsCytotoxin|DIF|Necrosin|Cachexin|TNFSF2|TNF|CachectinProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP06804SequenceMLRSSSQNSS DKPVAHVVAN HQVEEQLEWL SQRANALLAN GMDLKDNQLV VPADGLYLVY SQVLFKGQGC PDYVLLTHTV SRFAISYQEK VNLLSAVKSP CPKDTPEGAE LKPWYEPIYL GGVFQLEKGD QLSAEVNLPK YLDFAESGQV YFGVIALProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity Assay: Cytolysis of mouse L929 cells in the presence of Actinomycin D, ED₅₀ ≤0,1 ng/ml, Bioactivity ≥1,0×10⁷ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 50 mM sodium chloride, pH 7,5Molecular weight17,4 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay



