Human recombinant FGF21 (from E. coli)
Supplier: Shenandoah Biotechnology
About this item
Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.
- Animal-free
- Produced from genetically modified E. coli
- Monomeric protein containing 182 amino acids
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: This product is for research use only and is not for use in humans.
5 Options Available Below
Product Details & Documents
Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.
- Animal-free
- Produced from genetically modified E. coli
- Monomeric protein containing 182 amino acids
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: This product is for research use only and is not for use in humans.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT100-148AF-5UG
- SHBT100-148AF-20UG
- SHBT100-148AF100UG
- SHBT100-148AF500UG
- SHBT100-148AF-1MG
- Protein/peptide name:
- FGF21
- FGF21
- FGF-21
- FGF-21
- FGF21
- Protein synonyms:
- Fibroblast Growth Factor-21|FGF-21|FGFL
- Fibroblast Growth Factor-21|FGF-21|FGFL
- FGFL
- FGFL
- Fibroblast Growth Factor-21|FGF-21|FGFL
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Species:
- Human
- Human
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- Q9NSA1
- Q9NSA1
- Q9NSA1
- Q9NSA1
- Q9NSA1
- Sequence:
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
- Amino acid number:
- 182
- 182
- Protease-free:
- N
- N
- N
- N
- N
- Animal-free:
- Y
- Y
- Y
- Y
- Y
- Nuclease-free:
- N
- N
- N
- N
- N
- Carrier-free:
- Y
- Y
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- N
- N
- Endotoxin level:
- Low
- Low
- Low
- Low
- Low
- Endotoxin content:
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Endotoxin LAL (EU/µg) ≤0,1
- Biological activity:
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Bioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Grade:
- RUO
- RUO
- RUO
- RUO
- RUO
- Formulation:
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- 10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5
- Molecular weight:
- 19,5 kDa
- 19,5 kDa
- 19,5 kDa
- 19,5 kDa
- 19,5 kDa
- Reconstitution instructions:
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Storage conditions:
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- Shipping temperature:
- RT
- RT
- RT
- RT
- RT
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- Pack typePkAvailabilityPrice
- Specifications:
More
Specifications
Cat. No.SHBT100-148AF-5UGProtein/peptide nameFGF21Protein synonymsFibroblast Growth Factor-21|FGF-21|FGFLProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAmino acid numberProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molecular weight19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-148AF-20UGProtein/peptide nameFGF21Protein synonymsFibroblast Growth Factor-21|FGF-21|FGFLProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAmino acid numberProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molecular weight19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-148AF100UGProtein/peptide nameFGF-21Protein synonymsFGFLProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAmino acid number182Protease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molecular weight19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-148AF500UGProtein/peptide nameFGF-21Protein synonymsFGFLProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAmino acid number182Protease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molecular weight19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT100-148AF-1MGProtein/peptide nameFGF21Protein synonymsFibroblast Growth Factor-21|FGF-21|FGFLProtein/peptide typeRecombinantProtein functionCytokineSpeciesHumanSourceE. coliConjugationUnconjugatedGene IDQ9NSA1SequenceMHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY ASAmino acid numberProtease-freeNAnimal-freeYNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0,1Biological activityBioactivity assay: NIH-3T3 proliferation with β-klotho and heparin, ED50 ≤500 ng/ml, Bioactivity ≥2,0 ×10³ unit/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, 100 mM sodium chloride, pH 7,5Molecular weight19,5 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay