Anti-MECP2 Mouse Monoclonal Antibody [clone: 4F11]
BSENM-1809-100
- Antibody type:Primary
- Antigen name:Methyl-CpG binding protein 2 (MeCP2)
- Antigen symbol:MECP2
- Clonality:Monoclonal
- Clone:4F11
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG1
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Format:Purified IgG
- Form:Lyophilized
- Antigen synonyms:MeCp2|MeCp-2 protein
- UniProtKB:Uniprot # P51608
- Storage temperature:Store lyophilised antibody at 2-8 °C. After reconstitution divide into aliquots and store at –20 °C for long-term storage. Store at 2-8 °C short-term (up to 4 weeks) with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
- Shipping temperature:Ambient
- Immunogen:Full-length recombinant human protein
- Purification:Affinity purified
- Size:100 µg
- Pk:100 µG
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). Ref: uniprot.org
Western blotting (1:5,000-1:10,000) and Immunohistochemistry (1:1,000-1:5,000). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: MECP2
Clonality: Monoclonal
Clone: 4F11
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Rat