Mouse Recombinant PDGF-BB (from E. coli)
About this item
Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation.
- High quality
- Low endotoxin
- Affordable
IL-17AF signals through the IL-17RA/IL-17RC receptor complex and functions to regulate inflammatory responses. IL-17AF induces chemokine and airway neutrophilia production, similar in function to IL-17A and IL-17F homodimers. In regard to these functions, IL-17AF is less active than the IL-17A homodimer and shows greater activity than the IL-17F homodimer. Human and rat IL-17AF are active on mouse cells.
This functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. It is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues.
This dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB).
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
4 Options Available Below
Product Details & Documents
Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation.
- High quality
- Low endotoxin
- Affordable
IL-17AF signals through the IL-17RA/IL-17RC receptor complex and functions to regulate inflammatory responses. IL-17AF induces chemokine and airway neutrophilia production, similar in function to IL-17A and IL-17F homodimers. In regard to these functions, IL-17AF is less active than the IL-17A homodimer and shows greater activity than the IL-17F homodimer. Human and rat IL-17AF are active on mouse cells.
This functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. It is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues.
This dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB).
Delivery information: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Caution: For research use only.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- SHBT200-58-10UG
- SHBT200-58-100UG
- SHBT200-58-500UG
- SHBT200-58-1MG
- Protein/peptide name:
- PDGF-BB
- PDGF-BB
- PDGF-BB
- PDGF-BB
- Protein synonyms:
- ODGF|GDGF
- ODGF|GDGF
- ODGF|GDGF
- ODGF|GDGF
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Species:
- Mouse
- Mouse
- Mouse
- Mouse
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- P31240
- P31240
- P31240
- P31240
- Sequence:
- MSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVT
- MSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVT
- MSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVT
- MSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVT
- Protease-free:
- N
- N
- N
- N
- Animal-free:
- N
- N
- N
- N
- Nuclease-free:
- N
- N
- N
- N
- Carrier-free:
- Y
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- N
- Endotoxin level:
- Low
- Low
- Low
- Low
- Endotoxin content:
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- Endotoxin LAL (EU/µg) ≤1
- UniProtKB:
- P31240
- P31240
- P31240
- P31240
- Biological activity:
- Bioactivity assay: 3T3 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
- Bioactivity assay: 3T3 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
- Bioactivity assay: 3T3 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
- Bioactivity assay: 3T3 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Grade:
- RUO
- RUO
- RUO
- RUO
- Formulation:
- 10 mM sodium citrate, pH 3,0
- 10 mM sodium citrate, pH 3,0
- 10 mM sodium citrate, pH 3,0
- 10 mM sodium citrate, pH 3,0
- Molecular weight:
- 12,4/24,7 kDa
- 12,4/24,7 kDa
- 12,4/24,7 kDa
- 12,4/24,7 kDa
- Reconstitution instructions:
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Sterile water at 0,1 mg/ml
- Storage conditions:
- −20 °C
- −20 °C
- −20 °C
- −20 °C
- Shipping temperature:
- RT
- RT
- RT
- RT
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Specifications
Product Family Options
Product Information
- Pack typePkAvailabilityPrice
- Specifications:
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Specifications
Cat. No.SHBT200-58-10UGProtein/peptide namePDGF-BBProtein synonymsODGF|GDGFProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP31240SequenceMSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVTProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤1UniProtKBP31240Biological activityBioactivity assay: 3T3 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mgPurity≥95%GradeRUOFormulation10 mM sodium citrate, pH 3,0Molecular weight12,4/24,7 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-58-100UGProtein/peptide namePDGF-BBProtein synonymsODGF|GDGFProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP31240SequenceMSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVTProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤1UniProtKBP31240Biological activityBioactivity assay: 3T3 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mgPurity≥95%GradeRUOFormulation10 mM sodium citrate, pH 3,0Molecular weight12,4/24,7 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-58-500UGProtein/peptide namePDGF-BBProtein synonymsODGF|GDGFProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP31240SequenceMSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVTProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤1UniProtKBP31240Biological activityBioactivity assay: 3T3 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mgPurity≥95%GradeRUOFormulation10 mM sodium citrate, pH 3,0Molecular weight12,4/24,7 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay - Specifications:
More
Specifications
Cat. No.SHBT200-58-1MGProtein/peptide namePDGF-BBProtein synonymsODGF|GDGFProtein/peptide typeRecombinantProtein functionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP31240SequenceMSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVTProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤1UniProtKBP31240Biological activityBioactivity assay: 3T3 cell proliferation, ED50 ≤2 ng/ml, bioactivity ≥5,0×10⁵ units/mgPurity≥95%GradeRUOFormulation10 mM sodium citrate, pH 3,0Molecular weight12,4/24,7 kDaReconstitution instructionsSterile water at 0,1 mg/mlStorage conditions−20 °CShipping temperatureRTTested applicationsBioassay